PubHawk
July 1996 PMID 8828669

Muscle creatine loading in men.

E Hultman, K Söderlund, J A Timmons, G Cederblad, P L Greenhaff

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Mentions

50
Peak: 3 in Jan 2024
across 5 sources since May 2019

Extended reach

1,566,209
potential audience

Total likes

33,605

Video views

1,345,610

Mentions per month

May 2019 – Nov 2025

Where it's discussed

  • X / Twitter24 posts
  • News9 articles
  • YouTube6 videos
  • Facebook6 posts
  • Blogs5 articles

AI synopsis

What people are saying

The group collectively recognizes the study's confirmation that creatine loading with a higher dose initially increases muscle saturation, as seen in references to Hultman’s research, with some emphasizing the practical benefit of maintaining with lower doses. Interest and engagement are driven by debates on dosing safety, effectiveness, and long-term effects, with tone ranging from scientific to casual, reflecting a balanced mix of skepticism and acceptance of the research findings.

AgreementModerate agreement

Most discussions acknowledge the main findings of the study, especially regarding effective dosing and the physiology of creatine excretion.

InterestHigh interest

Participants show high interest by referencing past research, sharing personal experiences, and debating dosing strategies.

EngagementModerate engagement

Several posts actively analyze the research, cite other studies, and discuss practical implications, indicating moderate depth of engagement.

ImpactModerate impact

The discussions could influence supplement routines, especially around dosing and safety, marking a moderate impact on personal practices or opinions.

Abstract in brief

  • The study found that taking 20 grams of creatine daily for 6 days increases muscle creatine levels by about 20%, and then continuing with 2 grams per day maintains these elevated levels.
  • If supplementation stops, muscle creatine levels gradually return to baseline within about 30 days, with urinary creatinine excretion increasing during this period.
  • A smaller dose of 3 grams per day over 28 days can also effectively raise muscle creatine levels, making it a more gradual but still efficient method for creatine loading.]
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Top posts

Most liked on X and Bluesky
OJSN
@iamojsn · X

ちなみに、通常は1日3g程度を継続して摂取すれば十分だと思います。 Muscle creatine loading in men - PubMed - https://t.co/8fvEGewpnc

Apr 4, 2023 · 9 likes · 14,965 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/kDUNnKQjdK

Apr 11, 2024 · 8 likes · 4,219 followers View post →
Brett Singer MS,RD,CSSD
@BSinger10 · X

Muscle creatine loading in men https://t.co/GnchIIl2Ff

Apr 7, 2023 · 4 likes · 1 share · 2,819 followers View post →
Mike Matthews
@muscleforlife · X

To answer these questions, scientists at Queen's Medical Centre split 24 active male participants into 3 groups: https://t.co/ShPhnHT2ez

Sep 19, 2022 · 3 likes · 104,519 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

“if you take a lower dose of creatine by just a little bit longer period of time, you can also saturate the muscle with creatine” https://t.co/SSfYYeaGqu https://t.co/Ld3IqYhJtC

Nov 15, 2020 · 3 likes · 3,330 followers View post →
Tsukiyuki/スポーツ栄養
@Tsukiyuki6 · X

Today's reading

Jun 9, 2021 · 3 likes · 834 followers View post →

All mentions

BadLogicGoodLogic
@BadLogicGoodLog · X

@paulsaladinomd What is your thought on this study @paulsaladino? Muscle creatine loading in men E Hultman, K Soderlund, JA Timmons, G Cederblad, PL Greenhaff Journal of applied physiology 81 (1), 232-237, 1996 Do you have a written list of references I could read? https://t.co/L6VaPyf8Lg

Jul 6, 2025 · 41 followers View post →
Moe
@vvsmoe · X

@cocaine_bera @BearenstainBear @TrustlessState @Roubini18 @AgentChud Brother, we have known creatine gets excreted through urine past saturation for DECADES. Here is a study from 30 years ago already proving this. https://t.co/auebUW3EIB Even the most gymbro of gymbro’s knows you do a loading phase then maintain on a lower dose. Once the https://t.co/s7zq5zy3fg

Apr 20, 2025 · 993 followers View post →
Greg Nuckols
@GregNuckols · X

@FitFastCoach The thing people miss is that 5g/day is ALREADY a "better safe than sorry." The only applicable paper is Hultman (https://t.co/58IxPYr1IY), which found that 3g/day (about 0.04g/kg) was sufficient to maximize muscle creatine concentrations in under a month (cont.)

Nov 11, 2024 · 1 like · 14,905 followers View post →
Dr.ChikiDatos
@Em12016e · X

En: • Hultman, E., et. al. (1996). Muscle creatine loading in men. • Antonio, J., et. al. (2021). Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?.

Sep 6, 2024 · 89 followers View post →
Dr.ChikiDatos
@Em12016e · X

¿Se requiere una “fase de carga” de creatina al comenzar a tomarla?

Sep 6, 2024 · 89 followers View post →
DrAlvaroBustamante
@DrAlvaroBustam · X

1) E. Hultman et al. ´Muscle creatine loading in men`. J. Appl Physiol. 1996, pp. 232-7

Aug 20, 2024 · 31 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/kDUNnKQjdK

Apr 11, 2024 · 8 likes · 4,219 followers View post →
Javed Alam
@jalam1001 · X

RT @tecoughlin: Reference: https://t.co/CxX17P3FXP

Jan 2, 2024 · 1 share · 995 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/CxX17P3FXP

Jan 2, 2024 · 2 likes · 1 share · 4,219 followers View post →
Redmaddic
@redmaddic · X

@CorvixWasTaken I'd recommend looking on https://t.co/GtDFKUJfI4 for creatine loading specifically, you'll get many studies on the long-term effects as well. Here's an example that does disprove my claim partially, but also confirms that some ends up converting to urine https://t.co/38QuBUZeHx

Sep 21, 2023 · 1 like · 650 followers View post →
Brett Singer MS,RD,CSSD
@BSinger10 · X

Muscle creatine loading in men https://t.co/GnchIIl2Ff

Apr 7, 2023 · 4 likes · 1 share · 2,819 followers View post →
OJSN
@iamojsn · X

ちなみに、通常は1日3g程度を継続して摂取すれば十分だと思います。 Muscle creatine loading in men - PubMed - https://t.co/8fvEGewpnc

Apr 4, 2023 · 9 likes · 14,965 followers View post →
Darío Santana
@dariosantanatsd · X

Feb 16, 2023 · 375 followers View post →
Mike Matthews
@muscleforlife · X

To answer these questions, scientists at Queen's Medical Centre split 24 active male participants into 3 groups: https://t.co/ShPhnHT2ez

Sep 19, 2022 · 3 likes · 104,519 followers View post →
Brett Singer MS,RD,CSSD
@BSinger10 · X

Muscle creatine loading in men https://t.co/i49gOzo8em

Mar 12, 2022 · 2 likes · 2,819 followers View post →
galaxysplain
@galaxysplain · X

@ScepticalDoctor @NanciGuestRDPhD Correction, they did test 2g/day of supplementation in the same study & that was enough for maintenance. I'm not sure what the dietary intake of creatine was but I think it's usually not much more than 1 gram & often less than 1 gram even among non-vegans. https://t.co/5wfV8K4uLk

Oct 11, 2021 · 489 followers View post →
Ferruccio Balestreri
@0xferruccio · X

@kaimicahmills @raghavar0 @Mehdiyac Good to hear! I was cycling creatine when I said i did it, then learned it's fine to always take it https://t.co/o8UlP3CZeP

Aug 9, 2021 · 2 likes · 4,418 followers View post →
Tsukiyuki/スポーツ栄養
@Tsukiyuki6 · X

Today's reading

Jun 9, 2021 · 3 likes · 834 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

Start here and tell me why they are wrong. https://t.co/KCBVQJB7OT https://t.co/hsrbcj2mwG

Apr 23, 2021 · 3,330 followers View post →
Wendi A. Irlbeck MS, RDN, LD, CISSN
@Wendi_Irlbeck · X

RT @Creatine_FTW: @cbaxstar @MichaelAlbertMD @NanciGuestRDPhD @BioLayne @Wendi_Irlbeck Dr Albert, I’d encourage you to read the Hultman 199…

Dec 8, 2020 · 1 share · 54,024 followers View post →
Creatine_FTW
@Creatine_FTW · X

@cbaxstar @MichaelAlbertMD @NanciGuestRDPhD @BioLayne @Wendi_Irlbeck Dr Albert, I’d encourage you to read the Hultman 1996 “Muscle creatine loading in men” at https://t.co/zuhmRfGGyp 5g/d seems quite sufficient. Not an exhaustive list of Cr researchers on Twitter but check out @ScottForbes14 @darrencandow @JoseAntonioPhD @ZiegenfussTim @RBKreider https://t.co/CIQWlCquRe

Dec 8, 2020 · 3 likes · 1 share · 324 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

“if you take a lower dose of creatine by just a little bit longer period of time, you can also saturate the muscle with creatine” https://t.co/SSfYYeaGqu https://t.co/Ld3IqYhJtC

Nov 15, 2020 · 3 likes · 3,330 followers View post →
uae1ouy.
@uae1ouy · X

@lizossomos @sundezco é sério kk https://t.co/nGwL5ySSYL particularmente não vejo pq n saturar, em uma semana já começa a ter retorno, o q já faz vc treinar mais pesado o q traz mais resultado

Jun 1, 2020 · 1 like · 709 followers View post →
@Ap_Coach Amedio
@ap_coach · X

"...creatine...adolescent athlete

May 10, 2019 · 1,406 followers View post →