August 1977 PMID 911386

Plasma norepinephrine responses of man in cold water.

D G Johnson, J S Hayward, T P Jacobs, M L Collis, J D Eckerson, R H Williams

Mentions

22
Peak: 4 in Jan 2024
across 4 sources since Dec 2021

Extended reach

411,217
potential audience

Total likes

925

Video views

30,036

Mentions per month

Dec 2021 – Jul 2025

Where it's discussed

  • News10 articles
  • X / Twitter8 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The group demonstrates strong interest in the physiological effects of cold exposure, referencing specific mechanisms like norepinephrine release and dose-response effects, and using terms such as 'benefits,' 'activation,' and 'therapy.' The tone reflects curiosity and respect for scientific findings, highlighting the relevance of the study to personal health practices and broader physiological understanding.

AgreementModerate agreement

Most discussions acknowledge the validity of cold therapy and its physiological effects, referencing the article to support the benefits of norepinephrine release.

InterestHigh interest

The discussions show high interest, with posts asking about personal practices and noting potential benefits of cold therapy.

EngagementModerate engagement

Participants engage with the scientific content, discussing mechanisms like adrenergic activation and dose-response relationships, indicating a moderate level of deep engagement.

ImpactModerate impact

The posts suggest that the article influences ideas about cold therapy's impacts on the body's stress responses, though they stop short of claiming revolutionary change.

Abstract in brief

  • Cold water immersion triggers the sympathetic nervous system to release norepinephrine, with levels rising quickly and peaking around 45 minutes of exposure.
  • During the immersion, the body's metabolic rate increases threefold, and norepinephrine levels stay high until rewarming, which causes a brief spike followed by rapid decline.
  • The body's stress response to cold is quickly activated or suppressed based on skin temperature, and even if core temperature remains low, norepinephrine levels can change rapidly.]

Top posts

Most liked on X and Bluesky
Mark Hyman, M.D.
@drmarkhyman · X

What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 doi: 10.1080/22423982.2022.2111789 doi: 10.1016/j.xcrm.2021.100408 doi: 10.1210/jc.2013-3901 doi: 10.1152/jappl.1977.43.2.216 doi: 10.1016/j.mehy.2007.04.052

Jan 2, 2024 · 17 likes · 2 shares · 348,329 followers View post →
Thomas P Seager, PhD
@seagertp · X

Cold plunge therapy exhibits a dose-response curve. The more heat extracted, the greater the physiological response (in this data). The implication is that colder (or longer) can be better. https://t.co/N26r6uz6Vv @flexiblemandate

Feb 14, 2025 · 9 likes · 1 share · 13,209 followers View post →
Çınar Furkan İlhan
@cnarilhn · X

3) Adrenerjik sistemi aktive etme yolları: i) Soğuğa veya soğuk suya maruz kalmak https://t.co/aH8EddzJGo ii) Döngüsel hiperventilasyon https://t.co/QO104wplQc (20-25 kere hızlı hızlı nefes alıp vermek ve sonrasında 30 saniye nefesi tutmak ve bunu 3-4 kere tekrarlamak)

Apr 17, 2022 · 1 like · 57 followers View post →
Jeremy Murphy
@jeremypmurphy · X

RT @drmarkhyman: What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 d…

Jan 2, 2024 · 2 shares · 14,835 followers View post →
Joël Bomane
@JoelBomane · X

RT @drmarkhyman: What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 d…

Jan 2, 2024 · 2 shares · 2,323 followers View post →
Libertylover
@Libertyrespectr · X

RT @drmarkhyman: What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 d…

Jan 2, 2024 · 2 shares · 1,795 followers View post →

All mentions

ReadyPatientOne
@ReadyPatientOne · X

Jul 8, 2025 · 43 followers View post →
BillOckham
@BillOccham0 · X

RT @seagertp: Cold plunge therapy exhibits a dose-response curve. The more heat extracted, the greater the physiological response (in this…

Feb 14, 2025 · 1 share · 571 followers View post →
Thomas P Seager, PhD
@seagertp · X

Cold plunge therapy exhibits a dose-response curve. The more heat extracted, the greater the physiological response (in this data). The implication is that colder (or longer) can be better. https://t.co/N26r6uz6Vv @flexiblemandate

Feb 14, 2025 · 9 likes · 1 share · 13,209 followers View post →
Joël Bomane
@JoelBomane · X

RT @drmarkhyman: What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 d…

Jan 2, 2024 · 2 shares · 2,323 followers View post →
Libertylover
@Libertyrespectr · X

RT @drmarkhyman: What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 d…

Jan 2, 2024 · 2 shares · 1,795 followers View post →
Jeremy Murphy
@jeremypmurphy · X

RT @drmarkhyman: What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 d…

Jan 2, 2024 · 2 shares · 14,835 followers View post →
Mark Hyman, M.D.
@drmarkhyman · X

What kinds of cold therapy do you practice and what benefits have you noticed? Sources: doi: 10.1007/s00421-022-04915-5 doi: 10.1080/22423982.2022.2111789 doi: 10.1016/j.xcrm.2021.100408 doi: 10.1210/jc.2013-3901 doi: 10.1152/jappl.1977.43.2.216 doi: 10.1016/j.mehy.2007.04.052

Jan 2, 2024 · 17 likes · 2 shares · 348,329 followers View post →
Çınar Furkan İlhan
@cnarilhn · X

3) Adrenerjik sistemi aktive etme yolları: i) Soğuğa veya soğuk suya maruz kalmak https://t.co/aH8EddzJGo ii) Döngüsel hiperventilasyon https://t.co/QO104wplQc (20-25 kere hızlı hızlı nefes alıp vermek ve sonrasında 30 saniye nefesi tutmak ve bunu 3-4 kere tekrarlamak)

Apr 17, 2022 · 1 like · 57 followers View post →