September 1997 PMID 9284093

Different levels of 5alpha-reductase type I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia.

M E Sawaya, V H Price

Mentions

9
Peak: 3 in Nov 2023
across 3 sources since Oct 2023

Extended reach

119,435
potential audience

Total likes

2,450

Video views

118,911

Mentions per month

Oct 2023 – Feb 2025

Where it's discussed

  • YouTube6 videos
  • News2 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

The discussions highlight the relevance of the research in explaining gender-specific hair loss patterns, with some posts exploring the roles of enzymes such as 5-alpha-reductase and aromatase. The tone is scholarly yet accessible, with words like 'significant findings' and 'insights into hormonal influence,' which demonstrate active interest and recognition of the study's importance.

AgreementModerate agreement

Most discussions acknowledge the study’s findings, with some emphasizing its significance in understanding gender differences in hair loss.

InterestHigh interest

The discussions demonstrate high interest, as participants express curiosity about the mechanisms of androgen effects and the potential for future treatments.

EngagementModerate engagement

Comments often delve into interpretation of the results, referencing specific enzyme levels and hormone pathways, indicating moderate to deep engagement.

ImpactModerate impact

The posts reflect an awareness of the study’s importance for medical research and treatments for androgenetic alopecia, suggesting a moderate perceived impact.

Abstract in brief

  • The study analyzed hair follicles from 12 women and 12 men with androgenetic alopecia, focusing on levels of androgen receptors and enzymes involved in hormone metabolism, such as 5-alpha-reductase and aromatase.
  • Results showed that both genders had higher levels of androgen receptors and 5-alpha-reductase in the frontal scalp follicles compared to occipital ones, while aromatase was more abundant in occipital follicles.
  • Significant differences were found between men and women, with women showing lower androgen receptor and 5-alpha-reductase levels in frontal follicles but much higher aromatase levels, which may explain gender-specific patterns of hair loss.

Top posts

Most liked on X and Bluesky
原口 省吾
@HaraguchiShogo · X

毛包領域でステロイド代謝関連遺伝子の発現を解析した初期の論文。Different levels of 5alpha-reductase type I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia J Invest Dermatol. 1997 Sep;109(3):296-300.

Apr 2, 2024 · 2 likes · 526 followers View post →

All mentions

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This study measures finasteride, dutasteride, and DHT levels in hair tissue. Results show both drugs significantly lower DHT, with dutasteride having a stronger effect, demonstrating effective action in hair follicles…

Haircafe · Feb 27, 2025 50,469 views
原口 省吾
@HaraguchiShogo · X

毛包領域でステロイド代謝関連遺伝子の発現を解析した初期の論文。Different levels of 5alpha-reductase type I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia J Invest Dermatol. 1997 Sep;109(3):296-300.

Apr 2, 2024 · 2 likes · 526 followers View post →