PubHawk
November 1998 PMID 9809557

Neurogenesis in the adult human hippocampus.

P S Eriksson, E Perfilieva, T Björk-Eriksson, A M Alborn, C Nordborg, D A Peterson, F H Gage

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Mentions

168
Peak: 30 in Dec 2022
across 6 sources since Mar 2019

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483,270
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605

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Mar 2019 – Nov 2025

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AI synopsis

What people are saying

Throughout the discussions, many posts express support for the evidence of ongoing neurogenesis in the adult human hippocampus, using words like 'confirmation' and 'beautiful work' to show enthusiasm. Conversely, some posts question the significance and universality of neurogenesis, using phrases like 'minimal' and 'controversy,' which reflect the ongoing debate and subtle impact of these findings on the broader scientific community.

AgreementModerate agreement

Most discussions acknowledge and support the findings that adult neurogenesis occurs in the human hippocampus, indicating general consensus.

InterestHigh interest

The topic of adult hippocampal neurogenesis clearly draws significant attention, with many posts highlighting its implications for brain function.

EngagementModerate engagement

Posts involve references to scientific studies, debates, and different perspectives, suggesting a moderate level of engagement and understanding.

ImpactModerate impact

The discussion suggests that these findings could influence future research and understanding of neuroplasticity, though opinions vary about the extent of neurogenesis.

Abstract in brief

  • This study investigates whether new neurons are generated in the adult human hippocampus, similar to what is observed in rodents and monkeys, by analyzing postmortem brain tissue labeled with BrdU, a DNA marker for cell division.
  • The researchers found evidence of new neurons in the dentate gyrus of adult humans, as indicated by immunofluorescent labels for BrdU and neuronal markers like NeuN, calbindin, and NSE, suggesting ongoing neurogenesis.
  • The findings imply that the adult human hippocampus has the capacity to produce new neurons throughout life, challenging previous assumptions that neurogenesis does not occur in the adult human brain.]
Read the full abstract

Top posts

Most liked on X and Bluesky
د كريم على
@Fekrtany · X

Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البالغين وليس الاعتقاد السائد ان خلايا المخ ثابتة منذ الطفولة اطباء المخ والاعصاب ليتهم يفيدونا فى ذلك معجزات الجسم لاتنتهي #دكريم_على https://t.co/Jc512aAl4d

Dec 5, 2022 · 264 likes · 32 shares · 194,576 followers View post →
LlorensLab
@LlorensLab · X

We show that human dentate granule cells located in inner portions of the granule cell layer show less complex dendrites than those found in outer portions, which are presumably generated developmentally. These data support continuous neurogenesis in the adult human hippocampus https://t.co/qeqXf6IWxf

Aug 30, 2022 · 14 likes · 3 shares · 1,509 followers View post →
Naguib Mechawar
@naguibmechawar.bsky.social · Bluesky

Nice to see that this study confirms the results and conclusions we published last year on neurogenesis in the adult human hippocampus (see my pinned tweet). www.cell.com/cell-reports...

Mar 12, 2025 · 12 likes · 4 shares View post →
Martin RJ Ⓥ Fürholz ☠
@martinfuerholz · X

Hallo @spiegelonline - ich habe eine Anmerkung zu eurem Artikel https://t.co/rh6YU02vQ4 wo ihr berichtet, dass Forscher die Neurogenese entdeckt haben. *hust* Eriksson, P. S., et al. (1998). "Neurogenesis in the adult human hippocampus." Nature Medicine, 4(11), 1313–1317

Jul 4, 2025 · 11 likes · 2 shares · 2,759 followers View post →
Yicheng Wu
@yicheng_wu · X

A must read study from the ⁦@FrisenJonas⁩ lab came out in ⁦@ScienceMagazine⁩ and provided indisputable evidence of the existence of active neurogenesis in the adult human hippocampus. Beautiful work! Congrats to all authors

Jul 10, 2025 · 11 likes · 2 shares · 132 followers View post →
ルネサンス
@renaissance0168 · X

調味料(アミノ酸等)で脳の海馬の神経細胞ニューロンの損傷が起きても大人の脳の海馬でニューロンが新生する事が立証され↓心配要らない!?18歳で東大合格でもその後勉強しなければホリエモンごとく何一つ成し遂げられない!?大人になっても勉強すれば安藤忠雄のように大成可能!! https://t.co/Y2GgcjN1v4 https://t.co/OJU1D45Y96

Oct 17, 2024 · 7 likes · 1 share · 1,315 followers View post →

All mentions

pszKXqDO4W57357
@pszKXqDO4W57357 · X

@subama_ 可塑性・新生・構造/機能再編）    •   Neurogenesis in the adult human hippocampus. Nature Medicine, Eriksson et al.    •   Dynamics of hippocampal neurogenesis in adult humans. Cell, Spalding et al.    •   Human hippocampal neurogenesis persists throughout aging. Cell Stem

Nov 10, 2025 · 81 followers View post →
ルネサンス
@renaissance0168 · X

RT @renaissance0168: 調味料(アミノ酸等)で脳の海馬の神経細胞ニューロンの損傷が起きても大人の脳の海馬でニューロンが新生する事が立証され↓心配要らない!?18歳で東大合格でもその後勉強しなければホリエモンごとく何一つ成し遂げられない!?大人になっても勉強すれ…

Oct 18, 2025 · 1 share · 1,315 followers View post →
Jonas Frisén
@FrisenJonas · X

RT @yicheng_wu: A must read study from the ⁦@FrisenJonas⁩ lab came out in ⁦@ScienceMagazine⁩ and provided indisputable evidence of the exis…

Jul 11, 2025 · 2 shares · 823 followers View post →
Yicheng Wu
@yicheng_wu · X

A must read study from the ⁦@FrisenJonas⁩ lab came out in ⁦@ScienceMagazine⁩ and provided indisputable evidence of the existence of active neurogenesis in the adult human hippocampus. Beautiful work! Congrats to all authors

Jul 10, 2025 · 11 likes · 2 shares · 132 followers View post →
china Victims of Sinovac COVID-19 Vaccine
@lxub84387 · X

RT @martinfuerholz: Hallo @spiegelonline - ich habe eine Anmerkung zu eurem Artikel https://t.co/rh6YU02vQ4 wo ihr berichtet, dass Forscher…

Jul 4, 2025 · 2 shares · 532 followers View post →
Daniela
@Daniela45794841 · X

RT @martinfuerholz: Hallo @spiegelonline - ich habe eine Anmerkung zu eurem Artikel https://t.co/rh6YU02vQ4 wo ihr berichtet, dass Forscher…

Jul 4, 2025 · 2 shares · 1,470 followers View post →
Martin RJ Ⓥ Fürholz ☠
@martinfuerholz · X

Hallo @spiegelonline - ich habe eine Anmerkung zu eurem Artikel https://t.co/rh6YU02vQ4 wo ihr berichtet, dass Forscher die Neurogenese entdeckt haben. *hust* Eriksson, P. S., et al. (1998). "Neurogenesis in the adult human hippocampus." Nature Medicine, 4(11), 1313–1317

Jul 4, 2025 · 11 likes · 2 shares · 2,759 followers View post →
Naguib Mechawar
@naguibmechawar.bsky.social · Bluesky

Nice to see that this study confirms the results and conclusions we published last year on neurogenesis in the adult human hippocampus (see my pinned tweet). www.cell.com/cell-reports...

Mar 12, 2025 · 12 likes · 4 shares View post →
Updates in Medicine
@medic_updates · X

Mar 2, 2025 · 3 likes · 2,847 followers View post →
ルネサンス
@renaissance0168 · X

大人の脳の海馬(新たな記憶の形成に関与)で ニューロン(神経細胞)が 新しく生まれることが実証され 生涯を通じて人間の海馬で 神経細胞が生成されることが判明↓ 神経可塑性という 経験や学習により 神経細胞の繋がりや働きを 変える事もでき 脳を育てたり脳損傷を回復できる https://t.co/Y2GgcjN1v4

Oct 20, 2024 · 2 likes · 1,315 followers View post →
ルネサンス
@renaissance0168 · X

調味料(アミノ酸等)で脳の海馬の神経細胞ニューロンの損傷が起きても大人の脳の海馬でニューロンが新生する事が立証され↓心配要らない!?18歳で東大合格でもその後勉強しなければホリエモンごとく何一つ成し遂げられない!?大人になっても勉強すれば安藤忠雄のように大成可能!! https://t.co/Y2GgcjN1v4 https://t.co/OJU1D45Y96

Oct 17, 2024 · 7 likes · 1 share · 1,315 followers View post →
Krzysztof Potempa
@BRAINCURES · X

Neurogenesis in the adult human hippocampus Peter Eriksson, Ekaterina Perfilieva, Thomas Björk-Eriksson, Ann-Marie Alborn, Claes Nordborg, Daniel Peterson and Fred Gage @NatureMedicine 1998 https://t.co/HgIKszSjz3

Apr 17, 2024 · 2,667 followers View post →
Raffaele Di Giacomo, PhD
@sciqst · X

Neurogenesis in the adult human hippocampus remains a topic of significant interest and debate within the neuroscience community. The dynamic process of generating new neurons in this region of the brain is suggested to be pivotal for functions such as learning, memory, and https://t.co/I7owQDwBgk

Jan 31, 2024 · 9,358 followers View post →
bioRxiv Published
@biorxiv_pubd · X

Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human Hippocampus published as: https://t.co/HTGh7unXXB #IBRO_Reports #biorxiv

Aug 16, 2023 · 2,906 followers View post →
سلطان الحربي
@xg21c · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 16, 2022 · 32 shares · 91 followers View post →
سالمة
@salema__salema · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 14, 2022 · 32 shares · 533 followers View post →
Yara Elkady
@YaraElkady · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 9, 2022 · 32 shares · 194 followers View post →
مُطمئِنة الأطرش
@Safia_Being · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 6, 2022 · 32 shares · 245 followers View post →
Rehab alnahari
@rehab_alnahari · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 6, 2022 · 32 shares · 250 followers View post →
Eman
@EmanAlia11 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 240 followers View post →
HAYAT.Shحياة شبيب
@HAYAT_SH_18 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 30 followers View post →
amina k siefaldeen
@ameena_K_S · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 104 followers View post →
سمو السحاب ☁
@e333amr · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 299 followers View post →
يحيى حميدالكبيسي
@yhyyhmyd2 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 1,183 followers View post →
أم عبدالملك
@omkanze · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 26 followers View post →
Dark Moon
@YussufRourou · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 105 followers View post →
اسحاق نيوتن
@aannww22 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 489 followers View post →
Nesto Lamee
@LameeNesto · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 62 followers View post →
abderahamen
@abderahamen4 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 8 followers View post →
RANA AB
@RANAAB95172259 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 321 followers View post →
ن
@NoorMearaj · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 21 followers View post →
SULAIMAN ASIRI
@SULAIMANASIRI · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 101 followers View post →
Nada Hassanien
@HassanienNada · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 138 followers View post →
°•●~
@amal99022146 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 3,823 followers View post →
زهرة العائلة
@jUKXTjgRz4TyDT2 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 146 followers View post →
احمد
@26_hamada · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 180 followers View post →
Lubna abdlkader
@AbdlkaderLubna · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 409 followers View post →
Sahar Ahmad
@tt5375977 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 277 followers View post →
عبد اللطيف
@jandal77788 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 74 followers View post →
اللهم اجعل القرآن ربيع قلوبنا
@Video1Game · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 16 followers View post →
عماد الرشودي
@alomdh1065 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 1,053 followers View post →
Ibhar
@Ibhar26078345 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 143 followers View post →
عماد ابوالخيور
@emad5120 · X

RT @Fekrtany: Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البال…

Dec 5, 2022 · 32 shares · 359 followers View post →
د كريم على
@Fekrtany · X

Neurogenesis in the adult human hippocampus | Nature Medicine رسالة رائعة فى مجلة نيتشر عن ان خلايا المخ جديدة تنموا في البالغين وليس الاعتقاد السائد ان خلايا المخ ثابتة منذ الطفولة اطباء المخ والاعصاب ليتهم يفيدونا فى ذلك معجزات الجسم لاتنتهي #دكريم_على https://t.co/Jc512aAl4d

Dec 5, 2022 · 264 likes · 32 shares · 194,576 followers View post →
Academia Joven de España
@academia_joven · X

RT @LlorensLab: We show that human dentate granule cells located in inner portions of the granule cell layer show less complex dendrites th…

Sep 1, 2022 · 3 shares · 4,712 followers View post →
José Luis Trejo
@JLTrejo2 · X

RT @LlorensLab: We show that human dentate granule cells located in inner portions of the granule cell layer show less complex dendrites th…

Aug 30, 2022 · 3 shares · 2,338 followers View post →
Bogdan Draganski
@BogdanDraganski · X

RT @LlorensLab: We show that human dentate granule cells located in inner portions of the granule cell layer show less complex dendrites th…

Aug 30, 2022 · 3 shares · 852 followers View post →
LlorensLab
@LlorensLab · X

We show that human dentate granule cells located in inner portions of the granule cell layer show less complex dendrites than those found in outer portions, which are presumably generated developmentally. These data support continuous neurogenesis in the adult human hippocampus https://t.co/qeqXf6IWxf

Aug 30, 2022 · 14 likes · 3 shares · 1,509 followers View post →
Hawkeye Spirit
@World_All_Alive · X

RT @KruseYouri: The brain is amazing "Our results further indicate that the human hippocampus retains its ability to generate neurons thro…

Feb 6, 2022 · 1 share · 1,969 followers View post →
junglehoney
@KruseYouri · X

The brain is amazing "Our results further indicate that the human hippocampus retains its ability to generate neurons throughout life." Nature Medicine 4, 1313 – 1317 (1998) Neurogenesis in the adult human hippocampus

Feb 6, 2022 · 5 likes · 1 share · 13,379 followers View post →
Surojit Sural
@surojitsural · X

RT @Vasyl_Mykytiuk: No neurogenesis in the adult human hippocampus. The same is true for dolphins and bats. Interestingly, mice, pigs and m…

Feb 2, 2022 · 1 share · 880 followers View post →
Fun Pop Extra
@FunPopExtra · X

Neurogenesis in the adult human hippocampus | Nature Medicine https://t.co/pmO6ZQn79f

Jan 26, 2022 · 742 followers View post →
Vasyl Mykytiuk
@Vasyl_Mykytiuk · X

No neurogenesis in the adult human hippocampus. The same is true for dolphins and bats. Interestingly, mice, pigs and macaques do generate new neurons https://t.co/nX4QoZGOFb

Nov 21, 2021 · 1 like · 1 share · 318 followers View post →
thesharpestsphere
@thesharpestsph1 · X

@RussellSPierce @BadMedicalTakes Until 1998, yes Eriksson et al.: terminal cancer patients agreed to accept Brd-U (thymidine analog, when available gets built into DNA). Post-mortem sections showed humans did do what was known in rats since 70's - hippocampal nuerogenesis. So, yes. https://t.co/7r7OeJ0dPe

Jul 31, 2021 · 1 like · 262 followers View post →
Maria Ribeiro
@Mary_ORiver · X

RT @bxv_neurosci: Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human Hipp…

Jun 10, 2019 · 1 share · 10 followers View post →
bxv_neurosci
@bxv_neurosci · X

Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human Hippocampus https://t.co/XdFuaEDnE4

Jun 10, 2019 · 2 likes · 1 share · 1,048 followers View post →
vikas pareek
@vikaspareek · X

Small contribution by a team: @drashukumar @vikaspareek Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human Hippocampus https://t.co/IqDTORAVZq

Jun 10, 2019 · 1 like · 254 followers View post →
Julia B.
@JuliaB_fitness · X

RT @biorxivpreprint: Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human H…

Jun 10, 2019 · 3 shares · 2,259 followers View post →
Leighton H. Duncan
@LeightonHDuncan · X

RT @biorxivpreprint: Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human H…

Jun 10, 2019 · 3 shares · 314 followers View post →
Jim Johnson, PhD
@JimJohnsonSci · X

RT @biorxivpreprint: Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human H…

Jun 10, 2019 · 3 shares · 12,846 followers View post →
bioRxiv Neuroscience
@biorxiv_neursci · X

Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human Hippocampus https://t.co/VQ7djPu9yI #biorxiv_neursci

Jun 10, 2019 · 6 likes · 60,615 followers View post →
bioRxiv
@biorxivpreprint · X

Transcriptomic Analysis of the Neurogenesis Signature suggests Continued but Minimal Neurogenesis in the Adult Human Hippocampus https://t.co/Nbv8vpK0uw #bioRxiv

Jun 10, 2019 · 6 likes · 3 shares · 138,334 followers View post →
Oleg A. Chagin
@Oleg_A_Chagin · X

Neurogenesis in the adult human hippocampus. - PubMed - NCBI https://t.co/FpJegct7f4

Mar 26, 2019 · 1,132 followers View post →