December 1998 PMID 9863851

Intensive lifestyle changes for reversal of coronary heart disease.

D Ornish, L W Scherwitz, J H Billings, S E Brown, K L Gould, T A Merritt, S Sparler, W T Armstrong, T A Ports, R L Kirkeeide, C Hogeboom, R J Brand

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Mentions

184
Peak: 4 in Dec 2021
across 5 sources since Jun 2019

Extended reach

147,987
potential audience

Total likes

1,575

Video views

53,505

Mentions per month

Jun 2019 – Oct 2025

Where it's discussed

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AI synopsis

What people are saying

The group collectively emphasizes the significant findings of studies by Ornish and Esselstyn, particularly highlighting how plant-based diets can reverse coronary artery disease, demonstrated through phrases like 'showed to reverse' and 'evidence.' The tone is predominantly supportive and scientifically informed, with examples of deep engagement such as citing specific journal articles and criticizing misconceptions about animal product consumption, emphasizing the potential for lifestyle changes to impact heart health.

AgreementStrong agreement

Most discussions strongly support the efficacy of lifestyle changes and plant-based diets in reversing heart disease, citing studies like Ornish and Esselstyn’s work.

InterestHigh interest

Participants demonstrate high interest, referencing specific research, emphasizing diet impacts, and addressing misconceptions, indicating deep engagement with the topic.

EngagementHigh engagement

Many responses include detailed references to scientific studies, names of prominent doctors, and personal opinions, reflecting thorough exploration and discussion.

ImpactHigh impact

The discussions suggest that recognition of diet and lifestyle modifications as tools to combat heart disease could influence both public awareness and medical practices.

Abstract in brief

  • The Lifestyle Heart Trial showed that intensive lifestyle changes—including a vegetarian diet, exercise, stress management, smoking cessation, and psychosocial support—can lead to significant regression of coronary artery disease after 1 and 5 years, without the use of lipid-lowering drugs.
  • Most patients in the experimental group maintained these lifestyle changes over 5 years, resulting in a notable decrease in artery blockage and fewer cardiac events compared to the control group, which made only moderate changes.
  • The study concluded that sustained lifestyle modifications are both feasible for patients and effective in reducing coronary atherosclerosis and cardiac events over a 5-year period.

Top posts

Most liked on X and Bluesky
_toprak_
@toprak_mim · X

Video kaynağı: "Intensive Lifestyle Changes for Reversal of Coronary Heart Disease" (by @DeanOrnishMD and coworkers) https://t.co/p1vpMl4NHN

Nov 29, 2019 · 6 likes · 1,477 followers View post →
Agingdoc
@agingdoc1 · X

Intensive Lifestyle Changes for Reversal of Coronary Heart Disease (1998) @DeanOrnishMD https://t.co/ohql0r1xGa https://t.co/lUPUEX5YGm

Jan 16, 2023 · 5 likes · 43,835 followers View post →
Stefan Birkett, PhD
@Stefan_Birkett · X

Intensive Lifestyle Changes for Reversal of Coronary Heart Disease | Cardiology | JAMA | JAMA Network https://t.co/xpK2J8GE4c

Jan 22, 2020 · 4 likes · 2 shares · 659 followers View post →
Karim Samra
@KarimSamraAR · X

@PHL_Valentine @MsVanillaRose @ShortnBluntTho Whole plant foods are the only lifestyles shown to REVERSE heart disease, our number one killer Dr. Dean Ornish reversing heart disease with a WFPB diet https://t.co/Z48Ia7j3m9 Dr. Caldwell Esselstyn Jr reversing heart disease with a WFPB diet https://t.co/nu5vM9zhi1

Jan 1, 2024 · 4 likes · 2 shares · 144 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

@DrDamluji @nntaleb @IbeSaid @Spfannenschmidt @AlanHeldman https://t.co/wPpT76bnIf

Dec 5, 2021 · 3 likes · 5,368 followers View post →
Nick Hinkell
@Sninkelletti · X

@Claydencows @CarnivoreIs @of_skeptical @CarnAtheist @SustainableDish @MEATritionCom And how about this one, showing the first instance in which any intervention has reversed heart disease, the most deadly disease for humans: https://t.co/kyrFSrpwkv

Feb 21, 2023 · 3 likes · 142 followers View post →

All mentions

Maya
@Maya126873 · X

RT @JaydenAnker1: @DoctorTro Heart disease was reverse by nutrition in the 1990s . I wouldn’t get too excited :( . Nothing changed . https:…

Oct 16, 2025 · 1 share · 5,546 followers View post →
Jayden Anker
@JaydenAnker1 · X

@DoctorTro Heart disease was reverse by nutrition in the 1990s . I wouldn’t get too excited :( . Nothing changed . https://t.co/7DP7wFQrJ5

Oct 15, 2025 · 3 likes · 1 share · 29 followers View post →
kri2kumar
@KumarKrish59493 · X

@sakleo8 @drprashantmish6 https://t.co/TsHzVas4iz

Jun 18, 2025 · 82 followers View post →
Gaby and Health | Healthy Weight Loss
@Gaby_and_Health · X

@ApoDudz Dean Ornish: https://t.co/mSdqUQy0GD Esselstyn: https://t.co/Quew54BDFT A low-fat plant-based diet should be also included to see the effects of diet and not just drugs. Just my humble opinion.

May 14, 2025 · 1 like · 13 followers View post →
LeF
@Technoc32102406 · X

@RealSamBrokken Mij blokkeren gewoon doordat ik veel informatie post die uw cholesterol debunken. Dit gaat over mensen over hartziekte! Een wetenschapper onwaardig! https://t.co/AjunQeU7fJ U bent volledig mid met lowcarb en dierlijke producten!!! https://t.co/AjunQeU7fJ

Apr 12, 2025 · 56 followers View post →
Tropic Health
@tropic_health · X

@sminthel @VigilantFox @sminthel @VigilantFox JAMA 1998;280(23):2001-2007. DOI:10.1001/jama.280.23.2001. But since you asked so nicely, here's a spicy stat: Statins increase diabetes risk by 46% in postmenopausal women. Guess that's just bonus profit for pharma.

Apr 12, 2025 · 1,657 followers View post →
Tom Hyde
@CotsCardiology · X

@girishviswa @WALangProf @DrDerekConnolly @DrScottMurray @LondonCardiacCT @NickCurzen @mirvatalasnag @ColinBerryMD @HRahbi @danmckenzie73 Girish, It's an LAD, will post an update on DOTH (Day Of The Heart) ❤️ #valentinesday have a look at Dean Ornish https://t.co/vnSOAaNCEE won't be quite.tjst.dramatic ! Thanks Tom

Feb 6, 2025 · 2 likes · 1,554 followers View post →
Dr. Eddie Ramirez
@EddieRDMD · X

@EstebanDL @agargmd Link correcto: https://t.co/AuGBM7NoEh

Feb 4, 2025 · 4,903 followers View post →
Dr. Eddie Ramirez
@EddieRDMD · X

@agargmd @EstebanDL Aquí está el link correcto: https://t.co/AuGBM7NoEh

Feb 4, 2025 · 4,903 followers View post →
Stellasternchen
@Stellaster27074 · X

@NaveenSankarS @ifixhearts High intensity statin therapy/lipid lowering therapy can do that: https://t.co/K4pqmivLLd The only diet approach that showed reversal of plaque buildup in the coronary arteries was a vegetarian diet. (Within 5 years!). It was a small study though. https://t.co/mFbhc91tDi

Jan 27, 2025 · 13 followers View post →
Dalton Ebel
@RebelEbelDO · X

@Paddy_Barrett Ornish D, Scherwitz LW, Billings JH, et al. Intensive lifestyle changes for reversal of coronary heart disease [published correction appears in JAMA 1999;281(15):1380]. JAMA. 1998;280(23):2001-2007. doi:10.1001/jama.280.23.2001 You can reverse but Americans won’t change life.

Jan 6, 2025 · 1 like · 26 followers View post →
©anines tho™ ᕕ( ᐛ )ᕗ
@ShortnBluntTho · X

RT @KarimSamraAR: @PHL_Valentine @MsVanillaRose @ShortnBluntTho Whole plant foods are the only lifestyles shown to REVERSE heart disease, o…

Jan 1, 2024 · 2 shares · 5,961 followers View post →
Vanilla Robot (Ms)
@MsVanillaRose · X

RT @KarimSamraAR: @PHL_Valentine @MsVanillaRose @ShortnBluntTho Whole plant foods are the only lifestyles shown to REVERSE heart disease, o…

Jan 1, 2024 · 2 shares · 3,346 followers View post →
Karim Samra
@KarimSamraAR · X

@PHL_Valentine @MsVanillaRose @ShortnBluntTho Whole plant foods are the only lifestyles shown to REVERSE heart disease, our number one killer Dr. Dean Ornish reversing heart disease with a WFPB diet https://t.co/Z48Ia7j3m9 Dr. Caldwell Esselstyn Jr reversing heart disease with a WFPB diet https://t.co/nu5vM9zhi1

Jan 1, 2024 · 4 likes · 2 shares · 144 followers View post →
Karim Samra
@KarimSamraAR · X

@FiaOfFalcrenth @dennymishler @franalicee And physicians are healing their patients with it? Whole-food plant-based diets are the only diets shown to reverse heart disease: Dr. Dean Ornish and Dr. Caldwell Esselstyn Jr reversing heart disease with a WFPB diet; https://t.co/Z48Ia7j3m9 https://t.co/nu5vM9zhi1

Dec 26, 2023 · 144 followers View post →
Karim Samra
@KarimSamraAR · X

@ZMustavar @VegetariDan_ @Jeaia @TateTheTalisman Whole-food plant-based diets are the only diets shown to reverse heart disease, our number one killer! Dr. Dean Ornish reversing heart disease with a WFPB diet https://t.co/Z48Ia7j3m9 Dr. Caldwell Esselstyn Jr reversing heart disease with a WFPB diet https://t.co/nu5vM9zhi1

Dec 23, 2023 · 144 followers View post →
Karim Samra
@KarimSamraAR · X

@dennymishler @franalicee Whole-food plant-based diets are the only diets shown to reverse heart disease: Dr. Dean Ornish reversing heart disease with a WFPB diet https://t.co/Z48Ia7j3m9 Dr. Caldwell Esselstyn Jr reversing heart disease with a WFPB diet https://t.co/nu5vM9zhi1

Dec 19, 2023 · 144 followers View post →
LeF
@Technoc32102406 · X

@FatEmperor you reverse heart disease with your animal products? my god.. you are really delusional https://t.co/AjunQeU7fJ

Aug 26, 2023 · 56 followers View post →
Ernst Walter Henrich
@ErnstHenrich · X

‘Cured’ is indeed ‘strong’ but right: Ornish, et al. Intensive Lifestyle Changes for Reversal of Coronary Heart Disease. JAMA. 1998; Esselstyn, et al. A strategy to arrest + reverse coronary artery disease: a 5-year longitudinal study. The Journal of family practice, 41 6, 560-8. https://t.co/QT2MP7n0Lz

Jul 12, 2023 · 619 followers View post →
Ernst Walter Henrich
@ErnstHenrich · X

@DrAseemMalhotra ‘Cured’ is indeed ‘strong’ but right: Ornish, et al. Intensive Lifestyle Changes for Reversal of Coronary Heart Disease. JAMA. 1998; Esselstyn, et al. A strategy to arrest + reverse coronary artery disease: a 5-year longitudinal study. The Journal of family practice, 41 6, 560-8.

Jul 12, 2023 · 1 like · 619 followers View post →
Nick Hinkell
@Sninkelletti · X

@MyCreditABC @CarnivoreIs Have you ever looked into how much estrogen is in animal foods? Or the effects of dietary cholesterol and saturated fats on our blood flow? Animal consumption is why erectile dysfunction is a thing friend… it’s a symptom of heart disease. https://t.co/kyrFSrpwkv

Feb 22, 2023 · 142 followers View post →
Nick Hinkell
@Sninkelletti · X

@Claydencows @CarnivoreIs @of_skeptical @CarnAtheist @SustainableDish @MEATritionCom And how about this one, showing the first instance in which any intervention has reversed heart disease, the most deadly disease for humans: https://t.co/kyrFSrpwkv

Feb 21, 2023 · 3 likes · 142 followers View post →
Agingdoc
@agingdoc1 · X

Intensive Lifestyle Changes for Reversal of Coronary Heart Disease (1998) @DeanOrnishMD https://t.co/ohql0r1xGa https://t.co/lUPUEX5YGm

Jan 16, 2023 · 5 likes · 43,835 followers View post →
my pal doctorwise
@doctorwise · X

@Jacobiome @Libertas2008 @raphaels7 @KetoCarnivore @SBakerMD Yes and only diet to show reversal of coronary artery disease. Again, there were other interventions like exercise and smoking cessation. https://t.co/ZFgXcG4KK5

Nov 30, 2022 · 90 followers View post →
Chandrasekaran
@dramcsekar · X

@theliverdr I dont know of any evidence on raja yoga & reversal of atherosclerosis except https://t.co/svMiBFl3vy However, there are other yoga based programme shown to reverse atherosclerosis https://t.co/YKiEAceGph (JAMA) https://t.co/uTGPUPUn7W (Lancet) https://t.co/jhOeGXI3qo (JACC)

Sep 28, 2022 · 381 followers View post →
Teval
@Tevalbtc · X

@CRYPT0N1TE @GoingParabolic @DraganaMendel Yes, we know. https://t.co/awEyzahhly , https://t.co/SnmpB0b8CU . Gambling your lite on some instagram/twitter-diet sounds kind of stupid to me.

Jul 27, 2022 · 170 followers View post →
Peter Lansberg MDPhD
@lansberg · X

@eva3034385615 An old study (1998) shows the benefits of a low-fat diet on lipids (LDL, TG, and HDL-c) and angiographic improvements.... The Ornish lifestyle study. Please note the lipid changes and angiographic benefits in the participants 10.1001/jama.280.23.2001. https://t.co/gFSgcNndzx

Jul 15, 2022 · 1 like · 1 share · 2,643 followers View post →
Phlux
@PhluxKapacitor · X

@ChE_Engineer_TA @natbrunell N= 99, control arm on standard American diabetes assoc diet faired for worse then those in the low fat high carb plant based diet: https://t.co/9R0pbXQizD

Feb 2, 2022 · 925 followers View post →
Phlux
@PhluxKapacitor · X

@ChE_Engineer_TA @natbrunell 48 patients with coronary disease randomized. Plant based diet reversed disease, control arm of standard diet which actually increased disease: https://t.co/9R0pbXQizD

Feb 2, 2022 · 925 followers View post →
NO_TO_RIOT_BLOCKCHAIN_BITCOIN_MINE
@WitchesFor · X

Intensive Lifestyle Changes For Reversal of Coronary Heart Disease Dr @DeanOrnishMD https://t.co/Um2nfdyAVb

Jan 12, 2022 · 3,159 followers View post →
Pogiwog
@pogiwog · X

@MNaturalism @DishonestApe @StudentDocBen @theArdenHart @spicer_zack @Matt_Dillahunty Peer-reviewed journals. Here is more evidence: https://t.co/m5AYvjrA3c https://t.co/PZUhrblRjy https://t.co/TtX490SUpj https://t.co/QqKq4hYpcF

Dec 23, 2021 · 55 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

@DrDamluji @nntaleb @IbeSaid @Spfannenschmidt @AlanHeldman https://t.co/wPpT76bnIf

Dec 5, 2021 · 3 likes · 5,368 followers View post →
Ahinsa
@AhinsaMed · X

@nntaleb @Spfannenschmidt @DrDamluji https://t.co/4pb1YryHhA

Dec 4, 2021 View post →
Peyton Munno
@Peyton_Munno38 · X

Coronary artery disease may be the leading cause of death in the U.S. but did you know you can reverse CAD with lifestyle changes? This study and many more have shown that a healthy lifestyle can prevent and treat CAD #HRD #HPEX353_1 @HPEX353_1 https://t.co/48m12aULxk

Dec 3, 2021 · 2 likes View post →
Elena Sgarbossa MD Ⓥ
@ElenaSgarbossa · X

@EstebanDL Y dieta a base de plantas… aunque esta capacidad preventiva y a veces curativa de la dieta no se comente mucho en la fac de Medicina ni en la Cleveland Clinic (donde trabajé varios años), donde estuvo el pionero C. Esselstyn (amén de mi ex-jefe Favaloro) https://t.co/TngbUXq3lz

Jul 28, 2021 · 1 like · 2,699 followers View post →
Myriam
@MyriamSchorn · X

@drvyom @synapse101 Your messaging has reached the precision of NSW gouv. What is “moderation” ? For my father eating one meal/day without meat was moderation. Regarding the evidence…big blueberry has financed some good studies since https://t.co/PTR7y3TTFW Big kale doesn’t have the cash.

Jul 10, 2021 · 85 followers View post →
Abhishek Bhagat, MD
@abhagatmd · X

Which diet has shown to reverse heart disease? Intensive Lifestyle Changes for Reversal of Coronary Heart Disease https://t.co/8LIvEqj6Dj via @JAMA_current part of @JAMANetwork @DeanOrnishMD #vegan #vegetarian #cardiotwitter

Feb 12, 2021 · 55 followers View post →
Gropo Hillstrider
@gropo · X

@maxlugavere Actually

Jan 1, 2021 · 2 likes · 14 followers View post →
bahaia
@cryptojhhj · X

@kayfabeSuplex @SonOfTheSunNFTs @ridetheprotocol @saifedean There's no study showing you can reverse heart disease while eating animal products even if you have other healthy habits (exercise etc), but there is one showing a low fat plant based diet can: https://t.co/yBJeWiL17o

Dec 4, 2020 · 1 like · 131 followers View post →
Karen May
@karenmayphysio · X

RT @STB79: Intensive Lifestyle Changes for Reversal of Coronary Heart Disease | Cardiology | JAMA | JAMA Network https://t.co/xpK2J8GE4c

Jan 23, 2020 · 2 shares · 1,360 followers View post →
Stefan Birkett, PhD
@Stefan_Birkett · X

Intensive Lifestyle Changes for Reversal of Coronary Heart Disease | Cardiology | JAMA | JAMA Network https://t.co/xpK2J8GE4c

Jan 22, 2020 · 4 likes · 2 shares · 659 followers View post →
_toprak_
@toprak_mim · X

Video kaynağı: "Intensive Lifestyle Changes for Reversal of Coronary Heart Disease" (by @DeanOrnishMD and coworkers) https://t.co/p1vpMl4NHN

Nov 29, 2019 · 6 likes · 1,477 followers View post →
Nuria Granados
@Nuriabios · X

@alvaromg_ftw @jmmulet Ornish D, Scherwitz LW, Billings JH, Gould KL, Merritt TA, Sparler S, et al. Intensive Lifestyle Changes for Reversal of Coronary Heart Disease. JAMA. 1998;280(23):2001-7."

Jun 30, 2019 · 183 followers View post →