Publications by authors named "Aaron D Krabill"

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Discovery and Evaluation of Active Site-Directed, Potent, and Selective Sulfophenyl Acetic Amide-Based Inhibitors for the Laforin Phosphatase.
Jianping Lin, Rongjun He, Zihan Qu, Jiajun Dong, Aaron D Krabill

J Med Chem· May 2025

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Natural Product-Inspired Molecules for Covalent Inhibition of SHP2 Tyrosine Phosphatase.
Weida Liang, Aaron D Krabill, Katelyn S Gallagher, Christine Muli, Zihan Qu

Tetrahedron· April 2024

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Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
Ryan D Imhoff, Rishi Patel, Muhammad Hassan Safdar, Hannah B L Jones, Adan Pinto-Fernandez, Aaron D Krabill

J Med Chem· March 2024

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Altered Protein Dynamics and a More Reactive Catalytic Cysteine in a Neurodegeneration-associated UCHL1 Mutant.
Sebastian Kenny, Chih-Hsuan Lai, Tsung-Sheng Chiang, Kwame Brown, Chad S Hewitt, Aaron D Krabill

J Mol Biol· February 2024

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High-Throughput Discovery and Characterization of Covalent Inhibitors for Protein Tyrosine Phosphatases.
Zihan Qu, Aaron D Krabill, Zhong-Yin Zhang

Methods Mol Biol· December 2023

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Functional interrogation and therapeutic targeting of protein tyrosine phosphatases.
Aaron D Krabill, Zhong-Yin Zhang

Biochem Soc Trans· August 2021

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Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against .
Chad S Hewitt, Nader S Abutaleb, Ahmed E M Elhassanny, Alessio Nocentini, Xufeng Cao, Aaron D Krabill

ACS Infect Dis· July 2021

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Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1.
Aaron D Krabill, Hao Chen, Sajjad Hussain, Chad S Hewitt, Ryan D Imhoff

Molecules· February 2021

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Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant .
Jatinder Kaur, Xufeng Cao, Nader S Abutaleb, Ahmed Elkashif, Amanda L Graboski, Aaron D Krabill

J Med Chem· September 2020

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Development of Ubiquitin Variants with Selectivity for Ubiquitin C-Terminal Hydrolase Deubiquitinases.
Chad S Hewitt, Aaron D Krabill, Chittaranjan Das, Daniel P Flaherty

Biochemistry· September 2020

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Corrigendum: Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
Aaron D Krabill, Hao Chen, Sajjad Hussain, Chao Feng, Ammara Abdullah

Chembiochem· September 2020

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Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
Aaron D Krabill, Hao Chen, Sajjad Hussain, Chao Feng, Ammara Abdullah

Chembiochem· March 2020

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