Publications by authors named "Aaron Mackey"

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Risk-based Monitoring of Clinical Trials: An Integrative Approach.
Dimitris K Agrafiotis, Victor S Lobanov, Michael A Farnum, Eric Yang, Joseph Ciervo, Aaron J Mackey

Clin Ther· July 2018

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Using SQL Databases for Sequence Similarity Searching and Analysis.
William R Pearson, Aaron J Mackey

Curr Protoc Bioinformatics· September 2017

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Optimization of techniques for multiple platform testing in small, precious samples such as human chorionic villus sampling.
Margareta D Pisarska, Marzieh Akhlaghpour, Bora Lee, Gillian M Barlow, Ning Xu, Aaron J Mackey

Prenat Diagn· November 2016

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Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes.
Ylva Terelius, Robert A Figler, Svetlana Marukian, Maria S Collado, Mark J Lawson, Aaron J Mackey

Chem Biol Interact· August 2016

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Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma.
Brian J Capaldo, Devin Roller, Mark J Axelrod, Alex F Koeppel, Emanuel F Petricoin, Aaron J Mackey

PLoS One· May 2016

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Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.
Yan Ge, Suna Onengut-Gumuscu, Aaron R Quinlan, Aaron J Mackey, Jocyndra A Wright

Diabetes· March 2016

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Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.
Devin G Roller, Brian Capaldo, Stefan Bekiranov, Aaron J Mackey, Mark R Conaway

Oncotarget· January 2016

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Identification of a new target of miR-16, Vacuolar Protein Sorting 4a.
Neeta Adhikari, Weihua Guan, Brian Capaldo, Aaron J Mackey, Marjorie Carlson

PLoS One· December 2015

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An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation.
Banumathi K Cole, Michael B Simmers, Ryan Feaver, Charles W Qualls, M Sol Collado, Aaron Mackey

Arterioscler Thromb Vasc Biol· October 2015

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An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes.
Poonam R Sharma, Aaron J Mackey, Eden A Dejene, James W Ramadan, Carl D Langefeld

Endocrinology· September 2015

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BAYSIC: a Bayesian method for combining sets of genome variants with improved specificity and sensitivity.
Brandi L Cantarel, Daniel Weaver, Nathan McNeill, Jianhua Zhang, Aaron J Mackey

BMC Bioinformatics· April 2014

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Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma.
Devin G Roller, Mark Axelrod, Brian J Capaldo, Karin Jensen, Aaron Mackey

Mol Cancer Ther· November 2012

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Global changes in gene expression during compatible and incompatible interactions of cowpea (Vigna unguiculata L.) with the root parasitic angiosperm Striga gesnerioides.
Kan Huang, Karolina E Mellor, Shom N Paul, Mark J Lawson, Aaron J Mackey

BMC Genomics· August 2012

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Leptin protects host cells from Entamoeba histolytica cytotoxicity by a STAT3-dependent mechanism.
Chelsea S Marie, Hans P Verkerke, Shom N Paul, Aaron J Mackey, William A Petri

Infect Immun· May 2012

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The Drosophila melanogaster Genetic Reference Panel.
Trudy F C Mackay, Stephen Richards, Eric A Stone, Antonio Barbadilla, Julien F Ayroles, Aaron J Mackey

Nature· February 2012

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Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).
Jason E Stajich, Sarah K Wilke, Dag Ahrén, Chun Hang Au, Bruce W Birren, Aaron J Mackey

Proc Natl Acad Sci U S A· June 2010

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The genome of the model beetle and pest Tribolium castaneum.

Nature· April 2008

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Evigan: a hidden variable model for integrating gene evidence for eukaryotic gene prediction.
Qian Liu, Aaron J Mackey, David S Roos, Fernando C N Pereira

Bioinformatics· March 2008

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ToxoDB: an integrated Toxoplasma gondii database resource.
Bindu Gajria, Amit Bahl, John Brestelli, Jennifer Dommer, Steve Fischer, Aaron J Mackey

Nucleic Acids Res· January 2008

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Periplasmic proteins of the extremophile Acidithiobacillus ferrooxidans: a high throughput proteomics analysis.
An Chi, Lissette Valenzuela, Simon Beard, Aaron J Mackey, Jeffrey Shabanowitz

Mol Cell Proteomics· December 2007

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Creating a honey bee consensus gene set.
Christine G Elsik, Aaron J Mackey, Justin T Reese, Natalia V Milshina, David S Roos

Genome Biol· April 2007

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Assessing performance of orthology detection strategies applied to eukaryotic genomes.
Feng Chen, Aaron J Mackey, Jeroen K Vermunt, David S Roos

PLoS One· April 2007

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The genome of the sea urchin Strongylocentrotus purpuratus.

Science· November 2006

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Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii.
Asis Khan, Ulrike Böhme, Krystyna A Kelly, Ellen Adlem, Karen Brooks, Aaron J Mackey

Genome Res· September 2006

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Using relational databases for improved sequence similarity searching and large-scale genomic analyses.
Aaron J Mackey, William R Pearson

Curr Protoc Bioinformatics· October 2004

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