Publications by authors named "Aaron Randolph"

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Experimental factors that impact CaV1.2 channel pharmacology-Effects of recording temperature, charge carrier, and quantification of drug effects on the step and ramp currents elicited by the "step-step-ramp" voltage protocol.
Ming Ren, Aaron L Randolph, Claudia Alvarez-Baron, Donglin Guo, Phu N Tran

PLoS One· November 2022

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There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments.
Markus Rapedius, Alison Obergrussberger, Edward S A Humphries, Stephanie Scholz, Ilka Rinke-Weiss, Aaron Randolph

Front Mol Neurosci· August 2022

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Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block.
Phu N Tran, Jiansong Sheng, Aaron L Randolph, Claudia Alvarez Baron, Nicolas Thiebaud

PLoS One· December 2020

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A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.
Xiaomei Han, Mohammadreza Samieegohar, Bradley J Ridder, Wendy W Wu, Aaron Randolph

J Pharmacol Toxicol Methods· September 2020

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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Aaron Randolph

Toxicol Appl Pharmacol· May 2020

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Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Aaron Randolph

Toxicol Appl Pharmacol· May 2020

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Drug potency on inhibiting late Na current is sensitive to gating modifier and current region where drug effects were measured.
Min Wu, Phu N Tran, Jiansong Sheng, Aaron L Randolph, Wendy W Wu

J Pharmacol Toxicol Methods· March 2020

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Editor's Note: /Syntenin: A Positive Regulator of Melanoma Metastasis.
Habib Boukerche, Zao-Zhong Su, Luni Emdad, Patrick Baril, Brigitte Balme, Aaron Randolph

Cancer Res· October 2019

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Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative.
Zhihua Li, Bradley J Ridder, Xiaomei Han, Wendy W Wu, Jiansong Sheng, Aaron Randolph

Clin Pharmacol Ther· February 2019

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Decoy peptide targeted to Toll-IL-1R domain inhibits LPS and TLR4-active metabolite morphine-3 glucuronide sensitization of sensory neurons.
Yohance M Allette, Youngsook Kim, Aaron L Randolph, Jared A Smith, Matthew S Ripsch

Sci Rep· June 2017

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Proton currents constrain structural models of voltage sensor activation.
Aaron L Randolph, Younes Mokrab, Ashley L Bennett, Mark Sp Sansom, Ian Scott Ramsey

Elife· August 2016

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Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain.
Michael R Due, Xiao-Fang Yang, Yohance M Allette, Aaron L Randolph, Matthew S Ripsch

PLoS One· January 2016

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N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.
Moira Sauane, Pankaj Gupta, Irina V Lebedeva, Zao-Zhong Su, Devanand Sarkar, Aaron Randolph

Cancer Res· December 2006

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BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.
Pankaj Gupta, Mark R Walter, Zao-zhong Su, Irina V Lebedeva, Luni Emdad, Aaron Randolph

Cancer Res· August 2006

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Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.
Luni Emdad, Devanand Sarkar, Zao-zhong Su, Aaron Randolph, Habib Boukerche

Cancer Res· February 2006

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Molecular target-based therapy of pancreatic cancer.
Irina V Lebedeva, Devanand Sarkar, Zao-Zhong Su, Rahul V Gopalkrishnan, Mohammad Athar, Aaron Randolph

Cancer Res· February 2006

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mda-9/Syntenin: a positive regulator of melanoma metastasis.
Habib Boukerche, Zao-Zhong Su, Luni Emdad, Patrick Baril, Brigitte Balme, Aaron Randolph

Cancer Res· December 2005

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Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
Zhaozhong Su, Luni Emdad, Moira Sauane, Irina V Lebedeva, Devanand Sarkar, Aaron Randolph

Oncogene· November 2005

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Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice.
Devanand Sarkar, Zao-zhong Su, Nicolaq Vozhilla, Eun Sook Park, Aaron Randolph

Cancer Res· October 2005

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Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence.
Devanand Sarkar, Eun Sook Park, Luni Emdad, Aaron Randolph, Kristoffer Valerie

Mol Cell Biol· August 2005

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Potential molecular mechanism for rodent tumorigenesis: mutational generation of Progression Elevated Gene-3 (PEG-3).
Zao-zhong Su, Luni Emdad, Devanand Sarkar, Aaron Randolph, Kristofer Valerie

Oncogene· March 2005

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Targeting gene expression selectively in cancer cells by using the progression-elevated gene-3 promoter.
Zhao-Zhong Su, Devanand Sarkar, Luni Emdad, Gregory J Duigou, Charles S H Young, Aaron Randolph

Proc Natl Acad Sci U S A· January 2005

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Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.
Moira Sauane, Irina V Lebedeva, Zao-zhong Su, Heng-tong Choo, Aaron Randolph

Cancer Res· May 2004

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Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.
Dong-Chul Kang, Rahul V Gopalkrishnan, Lin Lin, Aaron Randolph, Kristoffer Valerie

Oncogene· March 2004

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