Publications by authors named "Aaron Sato"

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A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathway.
Linya Wang, Sean M Peterson, Marisa Yang, Ana G Lujan Hernandez, Tom Z Yuan, Aaron Sato

Oncogene· August 2025

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Phage display technology and its impact in the discovery of novel protein-based drugs.
Catherine J Hutchings, Aaron K Sato

Expert Opin Drug Discov· August 2024

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Discovery of a potent, selective, and tumor-suppressing antibody antagonist of adenosine A2A receptor.
Linya Wang, Pankaj Garg, Kara Y Chan, Tom Z Yuan, Ana G Lujan Hernandez, Aaron K Sato

PLoS One· June 2024

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A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variants.
Marisa L Yang, Tom Z Yuan, Kara Y Chan, Lin Ding, Zhen Han, Aaron K Sato

Antib Ther· April 2024

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Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for Treatment of Hyperinsulinism.
Sean M Peterson, Christine A Juliana, Cameron F Hu, Jinghua Chai, Carson Holliday, Aaron K Sato

Diabetes· September 2023

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Discovery and design of G protein-coupled receptor targeting antibodies.
Sean M Peterson, Catherine J Hutchings, Cameron F Hu, Melina Mathur, Janelle W Salameh, Aaron K Sato

Expert Opin Drug Discov· April 2023

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Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers.
Xiaofan Li, Sihong Zhou, Cristina L Abrahams, Stellanie Krimm, Jennifer Smith, Aaron K Sato

Mol Cancer Ther· February 2023

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Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.
Heather M Callaway, Kathryn M Hastie, Sharon L Schendel, Haoyang Li, Xiaoying Yu, Aaron K Sato

Cell Rep· January 2023

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Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries.
Tom Z Yuan, Pankaj Garg, Linya Wang, Jordan R Willis, Eric Kwan, Aaron K Sato

MAbs· January 2022

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Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study.
Kathryn M Hastie, Haoyang Li, Daniel Bedinger, Sharon L Schendel, S Moses Dennison, Aaron K Sato

Science· October 2021

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Rapid exploration of the epitope coverage produced by an Ebola survivor to guide the discovery of therapeutic antibody cocktails.
Tom Z Yuan, Ana G Lujan Hernandez, Erica Keane, Qiang Liu, Fumiko Axelrod, Aaron K Sato

Antib Ther· July 2020

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Immunization with cell-free-generated vaccine protects from Porphyromonas gingivalis-induced alveolar bone loss.
Nasi Huang, Elyse Shimomura, Gang Yin, Cuong Tran, Aaron Sato

J Clin Periodontol· February 2019

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Toward a Ferrous Iron-Cleavable Linker for Antibody-Drug Conjugates.
Benjamin Spangler, Toni Kline, Jeffrey Hanson, Xiaofan Li, Sihong Zhou, Aaron K Sato

Mol Pharm· May 2018

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Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail.
Jeffrey W Froude, Andrew S Herbert, Thibaut Pelat, Sebastian Miethe, Samantha E Zak, Aaron K Sato

Viruses· May 2018

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Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission.
Neeraj Kapoor, Ivana Vanjak, James Rozzelle, Aym Berges, Wei Chan, Aaron K Sato

Biochemistry· February 2018

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RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates.
Gang Yin, Heather T Stephenson, Junhao Yang, Xiaofan Li, Stephanie M Armstrong, Aaron K Sato

Sci Rep· June 2017

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Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis.
Nicolas V Currier, Shelley E Ackerman, James R Kintzing, Rishard Chen, Maria Filsinger Interrante, Aaron K Sato

Mol Cancer Ther· June 2016

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A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems.
Qi Cai, Jeffrey A Hanson, Alexander R Steiner, Cuong Tran, Mary Rose Masikat, Aaron K Sato

Biotechnol Prog· April 2016

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Methods to Make Homogenous Antibody Drug Conjugates.
Toni Kline, Alexander R Steiner, Kalyani Penta, Aaron K Sato, Trevor J Hallam

Pharm Res· November 2015

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Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system.
Yiren Xu, John Lee, Cuong Tran, Tyler H Heibeck, Willie D Wang, Aaron K Sato

MAbs· September 2015

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Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins.
Dan Groff, Stephanie Armstrong, Patrick J Rivers, Juan Zhang, Junhao Yang, Aaron K Sato

MAbs· May 2015

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Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Aaron Sato

Clin Cancer Res· May 2015

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A general sequence processing and analysis program for protein engineering.
Ryan L Stafford, Erik S Zimmerman, Trevor J Hallam, Aaron K Sato

J Chem Inf Model· October 2014

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In vitro Fab display: a cell-free system for IgG discovery.
Ryan L Stafford, Marissa L Matsumoto, Gang Yin, Qi Cai, Juan Jose Fung, Aaron K Sato

Protein Eng Des Sel· April 2014

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Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system.
Erik S Zimmerman, Tyler H Heibeck, Avinash Gill, Xiaofan Li, Christopher J Murray, Aaron K Sato

Bioconjug Chem· February 2014

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