Publications by authors named "Ada Tam"

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Murine gut microbiota dysbiosis via enteric infection modulates the foreign body response to a distal biomaterial implant.
Brenda Yang, Natalie Rutkowski, Anna Ruta, Elise Gray-Gaillard, David R Maestas, Ada Tam

Proc Natl Acad Sci U S A· May 2025

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Murine gut microbiota dysbiosis via enteric infection modulates the foreign body response to a distal biomaterial implant.
Brenda Yang, Natalie Rutkowski, Anna Ruta, Elise Gray-Gaillard, David R Maestas, Ada Tam

bioRxiv· January 2025

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Multidimensional Immunotyping of Human NF1-Associated Peripheral Nerve Sheath Tumors Uncovers Tumor-Associated Macrophages as Key Drivers of Immune Evasion in the Tumor Microenvironment.
Lindy Zhang, Alexandre Maalouf, Stavriani C Makri, Jineta Banerjee, Aditya Suru, Ada J Tam

Clin Cancer Res· December 2024

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Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity.
Hong Yu, Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo D A Vignali, Ada Tam

Elife· November 2024

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Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response.
Jin Han, Christopher Cherry, Joscelyn C Mejías, Kavita Krishnan, Anna Ruta, Ada J Tam

Adv Mater· October 2024

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Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity.
Hong Yu, Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo D A Vignali, Ada Tam

bioRxiv· August 2024

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Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers.
Monali Praharaj, Fan Shen, Alex J Lee, Liang Zhao, Thomas R Nirschl, Ada Tam

Cancer Immunol Res· July 2024

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Lung tumor-infiltrating T have divergent transcriptional profiles and function linked to checkpoint blockade response.
Arbor G Dykema, Jiajia Zhang, Laurene S Cheung, Sydney Connor, Boyang Zhang, Ada Tam

Sci Immunol· September 2023

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Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies.
Christopher Cherry, James I Andorko, Kavita Krishnan, Joscelyn C Mejías, Helen Hieu Nguyen, Ada J Tam

Geroscience· August 2023

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GOT1 constrains T17 cell differentiation, while promoting iT cell differentiation.
Wei Xu, Chirag H Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Ada J Tam

Nature· February 2023

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Cutting Edge: mTORC2 Regulates CD8+ Effector and Memory T Cell Differentiation through Serum and Glucocorticoid Kinase 1.
Chirag H Patel, Emily B Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Ada J Tam

J Immunol· December 2022

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Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors.
Fyza Y Shaikh, Joell J Gills, Fuad Mohammad, James R White, Courtney M Stevens, Ada Tam

Cancer Immunol Immunother· October 2022

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Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.
Julia L Drewes, Jie Chen, Nicholas O Markham, Reece J Knippel, Jada C Domingue, Ada J Tam

Cancer Discov· August 2022

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The effects of interventions to enhance cognitive and physical functions in older people with cognitive frailty: a systematic review and meta-analysis.
Ada Chung Ying Tam, Amanda Wan Yee Chan, Daphne Sze Ki Cheung, Lily Yuen Wah Ho, Angel Shuk Kwan Tang

Eur Rev Aging Phys Act· August 2022

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An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial.
Amy E Anderson, Iwen Wu, Alexis J Parrillo, Matthew T Wolf, David R Maestas, Ada J Tam

NPJ Regen Med· January 2022

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Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities.
Ilias Christodoulou, Won Jin Ho, Andrew Marple, Jonas W Ravich, Ada Tam

J Immunother Cancer· December 2021

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Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers.
Justina X Caushi, Jiajia Zhang, Zhicheng Ji, Ajay Vaghasia, Boyang Zhang, Ada Tam

Nature· October 2021

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Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers.
Justina X Caushi, Jiajia Zhang, Zhicheng Ji, Ajay Vaghasia, Boyang Zhang, Ada Tam

Nature· August 2021

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Bacterial-Driven Inflammation and Mutant Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.
Christina E DeStefano Shields, James R White, Liam Chung, Alyssa Wenzel, Jessica L Hicks, Ada J Tam

Cancer Discov· July 2021

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Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes.
John A Ligon, Woonyoung Choi, Gady Cojocaru, Wei Fu, Emily Han-Chung Hsiue, Ada J Tam

J Immunother Cancer· May 2021

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High-dimensional Cytometry (ExCYT) and Mass Spectrometry of Myeloid Infiltrate in Clinically Localized Clear Cell Renal Cell Carcinoma Identifies Novel Potential Myeloid Targets for Immunotherapy.
Debebe Theodros, Benjamin M Murter, John-William Sidhom, Thomas R Nirschl, David J Clark, Ada J Tam

Mol Cell Proteomics· November 2020

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IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis.
Heather J Faust, Hong Zhang, Jin Han, Matthew T Wolf, Ok Hee Jeon, Ada J Tam

J Clin Invest· October 2020

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The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures.
Lingling Chen, Teniola Oke, Nicholas Siegel, Gady Cojocaru, Ada J Tam

Clin Cancer Res· August 2020

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Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells.
Min-Hee Oh, Im-Hong Sun, Liang Zhao, Robert D Leone, Im-Meng Sun, Ada J Tam

J Clin Invest· July 2020

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Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans.
Liam Chung, David R Maestas, Andriana Lebid, Ashlie Mageau, Gedge D Rosson, Ada J Tam

Sci Transl Med· April 2020

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