Publications by authors named "Adam Burrack"

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IL-15 complex enhances therapeutic efficacy of anti-PD-L1 in a T cell-dependent and NK cell-independent manner in a murine model of pancreatic ductal adenocarcinoma.
Adam L Burrack, Alexander K Tsai, Madeline A Ellefson, Zoe C Schmiechen, Brandon M Larsen, Kristina S Burrack

J Immunol· December 2025

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Maturation of thymocytes with a monoclonal TCR under control of Trac promoter elements in the absence of β-selection.
Alexander K Tsai, Eduardo Cruz-Hinojoza, Madeline A Ellefson, Adam L Burrack, Brandon M Larsen

Immunohorizons· July 2025

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IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8+ T cells Infiltrating Pancreatic Ductal Adenocarcinoma.
Zoe C Schmiechen, Hezkiel A Nanda, Adam L Burrack, Grant H Hickok, Jonah Z Butler

Cancer Immunol Res· June 2025

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Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma.
Michael T Patterson, Adam L Burrack, Yingzheng Xu, Grant H Hickok, Zoe C Schmiechen

Cell Rep· July 2023

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Cxcr3 constrains pancreatic cancer dissemination through instructing T cell fate.
Adam L Burrack, Ellen J Spartz, Meagan R Rollins, Ebony A Miller, Maria Firulyova

Cancer Immunol Immunother· June 2023

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Germline T cell receptor exchange results in physiological T cell development and function.
Meagan R Rollins, Jackson F Raynor, Ebony A Miller, Jonah Z Butler, Ellen J Spartz, Adam L Burrack

Nat Commun· February 2023

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Genetic Engineering of Immune Evasive Stem Cell-Derived Islets.
Sara D Sackett, Samuel J Kaplan, Samantha A Mitchell, Matthew E Brown, Adam L Burrack

Transpl Int· December 2022

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Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer.
Adam L Burrack, Zoe C Schmiechen, Michael T Patterson, Ebony A Miller, Ellen J Spartz

JCI Insight· April 2022

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Insufficiency of compound immune checkpoint blockade to overcome engineered T cell exhaustion in pancreatic cancer.
Ingunn M Stromnes, Ayaka Hulbert, Meagan R Rollins, Ryan S Basom, Jeffrey Delrow, Adam L Burrack

J Immunother Cancer· February 2022

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Diverse Routes of Allograft Tolerance Disruption by Memory T Cells.
Ronald G Gill, Adam L Burrack

Front Immunol· June 2021

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An aged immune system drives senescence and ageing of solid organs.
Matthew J Yousefzadeh, Rafael R Flores, Yi Zhu, Zoe C Schmiechen, Robert W Brooks, Adam L Burrack

Nature· June 2021

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Chemotherapy brings virtual memory T cells into reality for cancer therapy.
Zoe C Schmiechen, Adam L Burrack, Ingunn M Stromnes

Cell Mol Immunol· May 2021

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CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model.
Adam L Burrack, Meagan R Rollins, Ellen J Spartz, Taylor D Mesojednik, Zoe C Schmiechen

J Immunol· March 2021

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Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma.
Adam L Burrack, Ellen J Spartz, Jackson F Raynor, Iris Wang, Margaret Olson

Cell Rep· August 2019

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Differential Effects of Depleting versus Programming Tumor-Associated Macrophages on Engineered T Cells in Pancreatic Ductal Adenocarcinoma.
Ingunn M Stromnes, Adam L Burrack, Ayaka Hulbert, Patrick Bonson, Cheryl Black

Cancer Immunol Res· June 2019

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Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.
Kevin C Osum, Adam L Burrack, Tijana Martinov, Nathanael L Sahli, Jason S Mitchell

Sci Rep· May 2018

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Simultaneous Recognition of Allogeneic MHC and Cognate Autoantigen by Autoreactive T Cells in Transplant Rejection.
Adam L Burrack, Laurie G Landry, Janet Siebert, Marilyne Coulombe, Ronald G Gill

J Immunol· February 2018

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Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides.
Adam L Burrack, Deepali Malhotra, Thamotharampillai Dileepan, Kevin C Osum, Linnea A Swanson

J Immunol· January 2018

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Increased Effector Memory Insulin-Specific CD4 T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.
Justin A Spanier, Nathanael L Sahli, Joseph C Wilson, Tijana Martinov, Thamotharampillai Dileepan, Adam L Burrack

Diabetes· December 2017

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T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.
Adam L Burrack, Tijana Martinov, Brian T Fife

Front Endocrinol (Lausanne)· December 2017

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Genetic ablation of arginase 1 in macrophages and neutrophils enhances clearance of an arthritogenic alphavirus.
Kristina A Stoermer, Adam Burrack, Lauren Oko, Stephanie A Montgomery, Luke B Borst

J Immunol· October 2012

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Expression and regulation of chemokines in murine and human type 1 diabetes.
Suparna A Sarkar, Catherine E Lee, Francisco Victorino, Tom T Nguyen, Jay A Walters, Adam Burrack

Diabetes· February 2012

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