Publications by authors named "Adam Palmer"

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Cross-resistance of Belinostat and Romidepsin in Non-T Follicular Helper Peripheral T-cell Lymphoma Models Suggests Subtype-Specific Implications for Belinostat-CHOP.
Jacob C Pantazis, Adam C Palmer

Mol Cancer Ther· December 2025

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A pharmacokinetic/pharmacodynamic model predicts tumor debulking improves CAR T-cell efficacy in Large B-Cell Lymphoma.
Amy E Pomeroy, Brian J Sworder, Deborah Plana, Yanguang Cao, Ash A Alizadeh, Adam C Palmer

Blood Cancer Discov· October 2025

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Integrating functional genomics and proteomics identifies Folate Carrier SLC19A1 as a predictor of pralatrexate sensitivity in T-cell lymphoma.
Jacob C Pantazis, Amy E Pomeroy, Adam C Palmer

bioRxiv· October 2025

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A Model of Intratumor and Interpatient Heterogeneity Explains Clinical Trials of Curative Combination Therapy for Lymphoma.
Amy E Pomeroy, Adam C Palmer

Blood Cancer Discov· May 2025

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An RNA damage response network mediates the lethality of 5-FU in colorectal cancer.
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Adam C Palmer

Cell Rep Med· October 2024

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Ultrasensitive Response Explains the Benefit of Combination Chemotherapy Despite Drug Antagonism.
Sarah C Patterson, Amy E Pomeroy, Adam C Palmer

Mol Cancer Ther· July 2024

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Synergistic Drug Combinations Promote the Development of Resistance in Acute Myeloid Leukemia.
Emily Mason-Osann, Amy E Pomeroy, Adam C Palmer, Jerome T Mettetal

Blood Cancer Discov· March 2024

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Tumor-Specific Activity of Precision Medicines in the NCI-MATCH Trial.
Ivvone Zhou, Deborah Plana, Adam C Palmer

Clin Cancer Res· February 2024

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Additivity predicts the efficacy of most approved combination therapies for advanced cancer.
Haeun Hwangbo, Sarah C Patterson, Andy Dai, Deborah Plana, Adam C Palmer

Nat Cancer· December 2023

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Genetically informed therapy for lymphoma: the discomfiting benefit of lumping splits.
Cynthia K Hahn, Adam C Palmer, David M Weinstock

Cancer Cell· October 2023

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Cell-of-Origin Subtypes and Therapeutic Benefit from Polatuzumab Vedotin.
Adam C Palmer, David M Kurtz, Ash A Alizadeh

N Engl J Med· August 2023

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An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types.
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Adam C Palmer

bioRxiv· April 2023

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Tumor-specific activity of precision medicines in the NCI-MATCH trial.
Ivvone Zhou, Deborah Plana, Adam C Palmer

medRxiv· March 2023

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Ultrasensitive response explains the benefit of combination chemotherapy despite drug antagonism.
Sarah C Patterson, Amy E Pomeroy, Adam C Palmer

bioRxiv· February 2023

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Drug independence and the curability of cancer by combination chemotherapy.
Amy E Pomeroy, Emmett V Schmidt, Peter K Sorger, Adam C Palmer

Trends Cancer· November 2022

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Predicting in vivo activity of combination therapies from in vitro drug pairs in diverse environments.
Sarah Patterson, Adam Palmer

Cell Rep Med· September 2022

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Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations.
Colin Hemez, Fabrizio Clarelli, Adam C Palmer, Christina Bleis, Sören Abel

Comput Struct Biotechnol J· August 2022

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Independent Drug Action in Combination Therapy: Implications for Precision Oncology.
Deborah Plana, Adam C Palmer, Peter K Sorger

Cancer Discov· March 2022

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Low diagnostic yield and time to diagnostic confirmation results in prolonged use of antimicrobials in critically ill children.
John Clark, Deborah White, Esther Daubney, Martin Curran, Rachel Bousfield, Adam Palmer

Wellcome Open Res· March 2022

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Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects.
Deborah Plana, Geoffrey Fell, Brian M Alexander, Adam C Palmer, Peter K Sorger

Nat Commun· February 2022

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Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors.
Adam C Palmer, Benjamin Izar, Haeun Hwangbo, Peter K Sorger

Clin Cancer Res· January 2022

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Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials.
Adam C Palmer, Deborah Plana, Peter K Sorger

Cell Syst· November 2020

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A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts.
Adam C Palmer, Deborah Plana, Hui Gao, Joshua M Korn, Guizhi Yang

Cancer Res· October 2020

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Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones.
Fabrizio Clarelli, Adam Palmer, Bhupender Singh, Merete Storflor, Silje Lauksund

PLoS Comput Biol· August 2020

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DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas.
Yonghan He, Raphael Koch, Vivekananda Budamagunta, Peiyi Zhang, Xuan Zhang, Adam C Palmer

J Hematol Oncol· July 2020

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