Publications by authors named "Adam Plaunt"

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Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection.
Donna M Konicek, Adam J Plaunt, Sachin Gharse, Sasha J Rose, Arielle Dorfman

Pharmaceutics· August 2023

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Correction for Plaunt et al., "Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections".
Adam J Plaunt, Sasha J Rose, Jeong Yeon Kang, Kuan-Ju Chen, Daniel LaSala

Antimicrob Agents Chemother· November 2022

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Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.
Michel R Corboz, Adam J Plaunt, Vladimir S Malinin, Zhili Li, Helena Gauani

J Pharmacol Exp Ther· October 2022

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Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension.
Michel R Corboz, Adam J Plaunt, Vladimir Malinin, Zhili Li, Helena Gauani

Eur J Pharmacol· February 2022

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Strategies to Overcome Biological Barriers Associated with Pulmonary Drug Delivery.
Adam J Plaunt, Tam L Nguyen, Michel R Corboz, Vladimir S Malinin, David C Cipolla

Pharmaceutics· January 2022

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Recent advances in prodrug-based nanoparticle therapeutics.
Kuan-Ju Chen, Adam J Plaunt, Franziska G Leifer, Jeong Yeon Kang, David Cipolla

Eur J Pharm Biopharm· August 2021

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Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
Adam J Plaunt, Sasha J Rose, Jeong Yeon Kang, Kuan-Ju Chen, Daniel LaSala

Antimicrob Agents Chemother· June 2021

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Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats.
Richard W Chapman, Zhili Li, Donald Chun, Helena Gauani, Vladimir Malinin, Adam J Plaunt

Pulm Pharmacol Ther· February 2021

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Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension.
Adam J Plaunt, Sadikul Islam, Tony Macaluso, Helena Gauani, Thomas Baker

Int J Mol Sci· January 2021

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Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil.
Richard W Chapman, Michel R Corboz, Carlos Fernandez, Eugene Sullivan, Andy Stautberg, Adam J Plaunt

ERJ Open Res· January 2021

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An overview of the biology of a long-acting inhaled treprostinil prodrug.
Richard W Chapman, Michel R Corboz, Vladimir S Malinin, Adam J Plaunt, Donna M Konicek

Pulm Pharmacol Ther· December 2020

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Inhaled Treprostinil-Prodrug Lipid Nanoparticle Formulations Provide Long-Acting Pulmonary Vasodilation.
Franziska G Leifer, Donna M Konicek, Kuan-Ju Chen, Adam J Plaunt, Dany Salvail

Drug Res (Stuttg)· November 2018

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Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil.
Richard W Chapman, Zhili Li, Michel R Corboz, Helena Gauani, Adam J Plaunt

Pulm Pharmacol Ther· April 2018

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Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.
Michel R Corboz, Zhili Li, Vladimir Malinin, Adam J Plaunt, Donna M Konicek

J Pharmacol Exp Ther· December 2017

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Evaluation of [¹¹¹In]-labeled zinc-dipicolylamine tracers for SPECT imaging of bacterial infection.
Douglas R Rice, Adam J Plaunt, Serhan Turkyilmaz, Miles Smith, Yuzhen Wang

Mol Imaging Biol· April 2015

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Chemically triggered release of 5-aminolevulinic acid from liposomes.
Adam J Plaunt, Kara M Harmatys, Kyle A Hendrie, Anthony J Musso, Bradley D Smith

RSC Adv· October 2014

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¹⁹F NMR indicator displacement assay using a synthetic receptor with appended paramagnetic relaxation agent.
Adam J Plaunt, Kasey J Clear, Bradley D Smith

Chem Commun (Camb)· September 2014

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Library synthesis, screening, and discovery of modified Zinc(II)-Bis(dipicolylamine) probe for enhanced molecular imaging of cell death.
Adam J Plaunt, Kara M Harmatys, William R Wolter, Mark A Suckow, Bradley D Smith

Bioconjug Chem· April 2014

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Enhanced cell death imaging using multivalent zinc(II)-bis(dipicolylamine) fluorescent probes.
Bryan A Smith, Kara M Harmatys, Shuzhang Xiao, Erin L Cole, Adam J Plaunt

Mol Pharm· September 2013

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Affinity and kinetic modulation of polyamide-DNA interactions by N-modification of the heterocycles.
Joseph P Ramos, Balaji Babu, Sameer Chavda, Yang Liu, Adam Plaunt

Biopolymers· August 2013

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Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides.
Sameer Chavda, Balaji Babu, Pravin Patil, Adam Plaunt, Amanda Ferguson

Bioorg Med Chem· July 2013

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Selective non-covalent triggered release from liposomes.
Adam J Plaunt, Meghan B Courbanou, Katrina D Cuison, Kara M Harmatys, Bradley D Smith

Chem Commun (Camb)· August 2012

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Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI.
Balaji Babu, Yang Liu, Adam Plaunt, Camille Riddering, Ross Ogilvie

Biochem Biophys Res Commun· January 2011

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