Publications by authors named "Adam Schrier"

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Discovery of Bis-Acyl Hydrazides as Potent and Bioavailable MTA-Cooperative PRMT5 Inhibitors: A Case Study of Leveraging the Deuterium Kinetic Isotope Effect.
Laurent Debien, Megan K Armstrong, Joshua D Farr, Ryan D Ferrao, Pancham Lal Gupta, Adam J Schrier

J Med Chem· December 2025

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Tracking HIV Rebound following Latency Reversal Using Barcoded HIV.
Matthew D Marsden, Tian-Hao Zhang, Yushen Du, Melanie Dimapasoc, Mohamed S A Soliman, Adam Schrier

Cell Rep Med· December 2020

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Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi.
James G Taylor, Sheila Zipfel, Kyla Ramey, Randy Vivian, Adam Schrier

Bioorg Med Chem Lett· August 2019

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Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle.
Richard L Mackman, Victoria A Steadman, David K Dean, Petr Jansa, Karine G Poullennec, Adam Schrier

J Med Chem· November 2018

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Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents.
Matthew D Marsden, Xiaomeng Wu, Sara M Navab, Brian A Loy, Adam J Schrier

Virology· July 2018

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In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
Matthew D Marsden, Brian A Loy, Xiaomeng Wu, Christina M Ramirez, Adam J Schrier

PLoS Pathog· September 2017

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Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death.
Daryl Staveness, Rana Abdelnabi, Adam J Schrier, Brian A Loy, Vishal A Verma

J Nat Prod· April 2016

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Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.
Brian A DeChristopher, Brian A Loy, Matthew D Marsden, Adam J Schrier, Jerome A Zack

Nat Chem· September 2012

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Bryostatin analogue-induced apoptosis in mantle cell lymphoma cell lines.
Ana Lopez-Campistrous, Xiaohua Song, Adam J Schrier, Paul A Wender, Nancy A Dower

Exp Hematol· August 2012

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Total synthesis of bryostatin 9.
Paul A Wender, Adam J Schrier

J Am Chem Soc· June 2011

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Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity.
Paul A Wender, Jeremy L Baryza, Stacey E Brenner, Brian A DeChristopher, Brian A Loy, Adam J Schrier

Proc Natl Acad Sci U S A· April 2011

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Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis.
Paul A Wender, Brian A Loy, Adam J Schrier

Isr J Chem· April 2011

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Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy.
Paul A Wender, Brian A Dechristopher, Adam J Schrier

J Am Chem Soc· May 2008

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