Publications by authors named "Adam Silverman"

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Transferrin receptor-targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA.
Michelle E Pizzo, Edward D Plowey, Nathalie Khoury, Wanda Kwan, Jordan Abettan, Adam P Silverman

Science· August 2025

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Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.
Spencer C Wei, Aaron J Cantor, Jack Walleshauser, Rina Mepani, Kory Melton, Adam P Silverman

PLoS One· June 2025

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Identification of a Guide RNA Targeting an Ultraconserved Element for Evaluation of Cas9 Genome Editors Across Mammalian Species.
Benjamin G Gowen, Prachi Khekare, Shannon R McCawley, Kory Melton, Craig Soares, Adam P Silverman

CRISPR J· December 2024

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Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.
Spencer C Wei, Aaron J Cantor, Jack Walleshauser, Rina Mepani, Kory Melton, Adam P Silverman

bioRxiv· December 2024

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An Automated Cell-Free Workflow for Transcription Factor Engineering.
Holly M Ekas, Brenda Wang, Adam D Silverman, Julius B Lucks, Ashty S Karim

ACS Synth Biol· October 2024

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Engineering a PbrR-Based Biosensor for Cell-Free Detection of Lead at the Legal Limit.
Holly M Ekas, Brenda Wang, Adam D Silverman, Julius B Lucks, Ashty S Karim

ACS Synth Biol· September 2024

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Identification of bacterial protease domains that cleave human IgM.
Tricia Windgassen, Nikki Kruse, Brian Ferrer, Faye Du, Hirdesh Kumar, Adam P Silverman

Enzyme Microb Technol· February 2024

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Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes.
Elizabeth A Phillips, Adam D Silverman, Aric Joneja, Michael Liu, Carl Brown

Nat Biomed Eng· December 2023

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Oral enzyme therapy for maple syrup urine disease (MSUD) suppresses plasma leucine levels in intermediate MSUD mice and healthy nonhuman primates.
Kristen Skvorak, Joyce Liu, Nikki Kruse, Roasa Mehmood, Subhamoy Das, Adam P Silverman

J Inherit Metab Dis· November 2023

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At-Home, Cell-Free Synthetic Biology Education Modules for Transcriptional Regulation and Environmental Water Quality Monitoring.
Jaeyoung K Jung, Blake J Rasor, Grant A Rybnicky, Adam D Silverman, Janet Standeven

ACS Synth Biol· October 2023

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An orally administered enzyme therapeutic for homocystinuria that suppresses homocysteine by metabolizing methionine in the gastrointestinal tract.
Kristen Skvorak, Vesna Mitchell, Leann Teadt, Kierra A Franklin, Hyung-Ok Lee, Adam P Silverman

Mol Genet Metab· August 2023

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Optimizing human α-galactosidase for treatment of Fabry disease.
William C Hallows, Kristen Skvorak, Nick Agard, Nikki Kruse, Xiyun Zhang, Adam P Silverman

Sci Rep· March 2023

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At-home, cell-free synthetic biology education modules for transcriptional regulation and environmental water quality monitoring.
Kirsten J Jung, Blake J Rasor, Grant A Rybnicky, Adam D Silverman, Janet Standeven

bioRxiv· January 2023

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Engineering a Synthetic Dopamine-Responsive Riboswitch for Biosensing.
Svetlana V Harbaugh, Adam D Silverman, Yaroslav G Chushak, Kathryn Zimlich, Monica Wolfe

ACS Synth Biol· July 2022

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APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.
Monica Xiong, Hong Jiang, Javier Remolina Serrano, Ernesto R Gonzales, Chao Wang, Adam P Silverman

Sci Transl Med· February 2021

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Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.
Julie C Ullman, Annie Arguello, Jennifer A Getz, Akhil Bhalla, Cathal S Mahon, Adam P Silverman

Sci Transl Med· May 2020

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Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys.
Mihalis S Kariolis, Robert C Wells, Jennifer A Getz, Wanda Kwan, Cathal S Mahon, Adam P Silverman

Sci Transl Med· May 2020

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Cell-free gene expression: an expanded repertoire of applications.
Adam D Silverman, Ashty S Karim, Michael C Jewett

Nat Rev Genet· March 2020

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Design and Optimization of a Cell-Free Atrazine Biosensor.
Adam D Silverman, Umut Akova, Khalid K Alam, Michael C Jewett, Julius B Lucks

ACS Synth Biol· March 2020

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Design of a Transcriptional Biosensor for the Portable, On-Demand Detection of Cyanuric Acid.
Xiangyang Liu, Adam D Silverman, Khalid K Alam, Erik Iverson, Julius B Lucks

ACS Synth Biol· January 2020

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Point-of-Use Detection of Environmental Fluoride a Cell-Free Riboswitch-Based Biosensor.
Walter Thavarajah, Adam D Silverman, Matthew S Verosloff, Nancy Kelley-Loughnane, Michael C Jewett

ACS Synth Biol· January 2020

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Organism Engineering for the Bioproduction of the Triaminotrinitrobenzene (TATB) Precursor Phloroglucinol (PG).
Adam Meyer, Ishtiaq Saaem, Adam Silverman, Vanessa A Varaljay, Rebecca Mickol

ACS Synth Biol· December 2019

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Point-of-care biomarker quantification enabled by sample-specific calibration.
Monica P McNerney, Yan Zhang, Paige Steppe, Adam D Silverman, Michael C Jewett

Sci Adv· September 2019

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Deconstructing Cell-Free Extract Preparation for in Vitro Activation of Transcriptional Genetic Circuitry.
Adam D Silverman, Nancy Kelley-Loughnane, Julius B Lucks, Michael C Jewett

ACS Synth Biol· February 2019

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Incorporating telemedicine into the integrated care of the COPD patient a summary of an interdisciplinary workshop held in Stresa, Italy, 7-8 September 2017.
Claudio F Donner, Jonathan Raskin, Richard ZuWallack, Linda Nici, Nicolino Ambrosino, Adam R Silverman

Respir Med· October 2018

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