Publications by authors named "Adam Yokom"

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A Metabolic Complex Involved in Tomato Specialized Metabolism.
Varun Dwivedi, Ernest Okertchiri, Adam Yokom, Craig A Schenck

bioRxiv· February 2025

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Design principles to tailor Hsp104 therapeutics.
JiaBei Lin, Peter J Carman, Craig W Gambogi, Nathan M Kendsersky, Edward Chuang, Adam L Yokom

Cell Rep· December 2024

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Design principles to tailor Hsp104 therapeutics.
JiaBei Lin, Peter J Carman, Craig W Gambogi, Nathan M Kendsersky, Edward Chuang, Adam L Yokom

bioRxiv· April 2024

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Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation.
Xuefeng Ren, Thanh N Nguyen, Wai Kit Lam, Cosmo Z Buffalo, Michael Lazarou, Adam L Yokom

Sci Adv· February 2023

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Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation.
Rachel M Jansen, Roberta Peruzzo, Simon A Fromm, Adam L Yokom, Roberto Zoncu

Sci Adv· September 2022

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Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1.
A King Cada, Mark R Pavlin, Juan P Castillo, Alexander B Tong, Kevin P Larsen, Adam L Yokom

Proc Natl Acad Sci U S A· July 2022

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Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy.
Chunmei Chang, Xiaoshan Shi, Liv E Jensen, Adam L Yokom, Dorotea Fracchiolla

Sci Adv· April 2021

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The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment.
Xiaoshan Shi, Chunmei Chang, Adam L Yokom, Liv E Jensen, James H Hurley

Elife· August 2020

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ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer.
Xiaoshan Shi, Adam L Yokom, Chunxin Wang, Lindsey N Young, Richard J Youle

J Cell Biol· July 2020

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A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.
Thomas G Flower, Yoshinori Takahashi, Arpa Hudait, Kevin Rose, Nicholas Tjahjono, Adam L Yokom

Nat Struct Mol Biol· June 2020

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Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Rosalie E Lawrence, Simon A Fromm, Yangxue Fu, Adam L Yokom, Do Jin Kim

Science· November 2019

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Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
Benjamin G Horst, Adam L Yokom, Daniel J Rosenberg, Kyle L Morris, Michal Hammel

Elife· September 2019

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Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity.
Amber Tariq, JiaBei Lin, Meredith E Jackrel, Christina D Hesketh, Peter J Carman, Adam L Yokom

Cell Rep· August 2019

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Allosteric Regulation of Oligomerization by a B Trafficking G-Protein Is Corrupted in Methylmalonic Aciduria.
Markus Ruetz, Gregory C Campanello, Liam McDevitt, Adam L Yokom, Pramod K Yadav

Cell Chem Biol· July 2019

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The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis.
Haoming Zhang, Adam L Yokom, Shen Cheng, Min Su, Paul F Hollenberg

J Biol Chem· May 2018

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Switch I-dependent allosteric signaling in a G-protein chaperone-B enzyme complex.
Gregory C Campanello, Michael Lofgren, Adam L Yokom, Daniel R Southworth, Ruma Banerjee

J Biol Chem· October 2017

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Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.
Stephanie N Gates, Adam L Yokom, JiaBei Lin, Meredith E Jackrel, Alexandrea N Rizo

Science· July 2017

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Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation.
Adam L Yokom, Stephanie N Gates, Meredith E Jackrel, Korrie L Mack, Min Su

Nat Struct Mol Biol· September 2016

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Biophysical characterization data on Aβ soluble oligomers produced through a method enabling prolonged oligomer stability and biological buffer conditions.
Amanda C Crisostomo, Loan Dang, Jyothi L Digambaranath, Andrea C Klaver, David A Loeffler, Adam L Yokom

Data Brief· September 2015

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Kinetic analysis of IgG antibodies to beta-amyloid oligomers with surface plasmon resonance.
Amanda C Crisostomo, Loan Dang, Jyothi L Digambaranath, Andrea C Klaver, David A Loeffler, Adam L Yokom

Anal Biochem· July 2015

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The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Marcelo J Murai, Jonathan Pollock, Shihan He, Hongzhi Miao, Trupta Purohit, Adam Yokom

Blood· December 2014

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Architecture of the nitric-oxide synthase holoenzyme reveals large conformational changes and a calmodulin-driven release of the FMN domain.
Adam L Yokom, Yoshihiro Morishima, Miranda Lau, Min Su, Alisa Glukhova

J Biol Chem· June 2014

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