Publications by authors named "Adi D Dubash"

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The desmosomal cadherin Desmoglein-2 controls extracellular matrix expression and remodeling via NF-κB signaling in keratinocytes.
Sadie E Hunter, Zara T Patel, Beatriz Mateo, Joshua M Powers, Austin Y Shull, Adi D Dubash

Front Cell Dev Biol· November 2025

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Susceptibility to innate immune activation in genetically mediated myocarditis.
Daniel F Selgrade, Dominic E Fullenkamp, Ivana A Chychula, Binjie Li, Lisa Dellefave-Castillo, Adi D Dubash

J Clin Invest· May 2024

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Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion.
W Tucker Shelton, S Madison Thomas, Hunter R Alexander, C Evan Thomes, Daniel E Conway, Adi D Dubash

Sci Rep· June 2021

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Desmoplakin Harnesses Rho GTPase and p38 Mitogen-Activated Protein Kinase Signaling to Coordinate Cellular Migration.
Jacqueline L Bendrick, Luke A Eldredge, Erica I Williams, Nick B Haight, Adi D Dubash

J Invest Dermatol· June 2019

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Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43.
Chen Yuan Kam, Adi D Dubash, Elisa Magistrati, Simona Polo, Karla J F Satchell

J Cell Biol· September 2018

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Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.
Adi D Dubash, Chen Y Kam, Brian A Aguado, Dipal M Patel, Mario Delmar

J Cell Biol· February 2016

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Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions.
Dipal M Patel, Adi D Dubash, Geri Kreitzer, Kathleen J Green

J Cell Biol· September 2014

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The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1.
Adi D Dubash, Jennifer L Koetsier, Evangeline V Amargo, Nicole A Najor, Robert M Harmon

J Cell Biol· August 2013

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Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.
Robert M Harmon, Cory L Simpson, Jodi L Johnson, Jennifer L Koetsier, Adi D Dubash

J Clin Invest· April 2013

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Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus.
Christophe Guilluy, Adi D Dubash, Rafael García-Mata

Nat Protoc· December 2011

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Desmosomes.
Adi D Dubash, Kathleen J Green

Curr Biol· July 2011

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The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals.
Adi D Dubash, Christophe Guilluy, Melissa C Srougi, Etienne Boulter, Keith Burridge

PLoS One· February 2011

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Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling.
Viktor Todorović, Bhushan V Desai, Melanie J Schroeder Patterson, Evangeline V Amargo, Adi D Dubash

J Cell Sci· October 2010

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Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation.
Matt D Medlin, Dean P Staus, Adi D Dubash, Joan M Taylor, Christopher P Mack

Arterioscler Thromb Vasc Biol· September 2010

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Plakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA.
Lisa M Godsel, Adi D Dubash, Amanda E Bass-Zubek, Evangeline V Amargo, Jodi L Klessner

Mol Biol Cell· August 2010

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Chapter 1. Focal adhesions: new angles on an old structure.
Adi D Dubash, Marisa M Menold, Thomas Samson, Etienne Boulter, Rafael García-Mata

Int Rev Cell Mol Biol· January 2010

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The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.
Rafael García-Mata, Adi D Dubash, Lisa Sharek, Heather S Carr, Jeffrey A Frost

Mol Cell Biol· December 2007

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A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin.
Adi D Dubash, Krister Wennerberg, Rafael García-Mata, Marisa M Menold, William T Arthur

J Cell Sci· November 2007

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