Publications by authors named "Adrian B McDermott"

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Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022-23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study.
Hai Nguyen-Tran, Sang Woo Park, Matthew R Vogt, Perdita Permaul, Alicen B Spaulding, Adrian B McDermott

Lancet Infect Dis· January 2026

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Establishing long-lasting vaccine immunity: insights from mRNA and adjuvanted protein platforms.
Andrea-Clemencia Pineda-Peña, Kohei Hasegawa, Vincent Pavot, Catherine Berry, Behazine Combadière, Adrian B McDermott

NPJ Vaccines· December 2025

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Pharmacokinetics Analysis of Serum and Rectal Tissue Concentrations of a Pair of Anti-HIV Monoclonal Antibodies, VRC01 and VRC01LS, in Adults Without HIV.
Yunda Huang, Lily Zhang, Maria P Lemos, Rena D Astronomo, Sandeep Narpala, Adrian B McDermott

J Clin Pharmacol· November 2025

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The N terminus of H3-influenza hemagglutinin as a site-of-vulnerability to neutralizing antibody.
Reda Rawi, Nicholas C Morano, Crystal Sao-Fong Cheung, Haijuan Du, Jason Gorman, Adrian B McDermott

Structure· November 2025

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Immune correlates analysis of antibody responses against SARS-CoV-2 variants in the ENSEMBLE vaccine efficacy trial.
Alex Luedtke, Youyi Fong, Lars van der Laan, Fei Heng, Ying Huang, Adrian B McDermott

iScience· November 2025

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Prospective SARS-CoV-2 additional vaccination in immunosuppressant-treated individuals with autoimmune diseases in a randomized controlled trial.
Meggan Mackay, Catriona A Wagner, Ashley Pinckney, Jeffrey A Cohen, Zachary S Wallace, Adrian B McDermott

JCI Insight· November 2025

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Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies.
Julia Lederhofer, Andrew J Borst, Lam Nguyen, Rebecca A Gillespie, Connor J Williams, Adrian B McDermott

Nat Commun· August 2025

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Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans.
Jordan R Willis, Madhu Prabhakaran, Michelle Muthui, Ansuya Naidoo, Troy Sincomb, Adrian B McDermott

Science· July 2025

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Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Tom G Caniels, Madhu Prabhakaran, Gabriel Ozorowski, Kellie J MacPhee, Weiwei Wu, Adrian B McDermott

Science· July 2025

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Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults.
Richard L Wu, Katherine V Houser, Martin R Gaudinski, Alicia T Widge, Seemal F Awan, Adrian B McDermott

Lancet HIV· July 2025

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Early influenza virus exposure shapes the B cell response to influenza vaccination in individuals 50 years later.
Abby Spangler, Geoffrey D Shimberg, Grace E Mantus, Rory Malek, Lauren Y Cominsky, Adrian B McDermott

Immunity· March 2025

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Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350.
M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adrian B McDermott

Immunity· February 2025

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Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection.
Myra Happe, Rebecca M Lynch, Carl J Fichtenbaum, Sonya L Heath, Susan L Koletar, Adrian B McDermott

JCI Insight· February 2025

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Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem-specific human B cells.
Grace E Mantus, Ankita J Chopde, Jason Gorman, Lauren Y Cominsky, Amine Ourahmane, Adrian B McDermott

Sci Transl Med· January 2025

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Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial.
Boris Julg, Victoria E K Walker-Sperling, Kshitij Wagh, Malika Aid, Kathryn E Stephenson, Adrian B McDermott

Nat Med· December 2024

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Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies.
Julia Lederhofer, Andrew J Borst, Lam Nguyen, Rebecca A Gillespie, Connor J Williams, Adrian B McDermott

bioRxiv· December 2024

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Neutralizing antibody correlate of protection against severe-critical COVID-19 in the ENSEMBLE single-dose Ad26.COV2.S vaccine efficacy trial.
Lindsay N Carpp, Ollivier Hyrien, Youyi Fong, David Benkeser, Sanne Roels, Adrian B McDermott

Nat Commun· November 2024

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Enhanced and sustained biodistribution of HIV-1 neutralizing antibody VRC01LS in human genital and rectal mucosa.
Maria P Lemos, Rena D Astronomo, Yunda Huang, Sandeep Narpala, Madhu Prabhakaran, Adrian B McDermott

Nat Commun· November 2024

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Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine.
Joseph P Casazza, Amelia R Hofstetter, Pamela J M Costner, LaSonji A Holman, Cynthia S Hendel, Adrian B McDermott

NPJ Vaccines· September 2024

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Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.
Tom G Caniels, Max Medina-Ramìrez, Shiyu Zhang, Sven Kratochvil, Yuejiao Xian, Adrian B McDermott

Sci Immunol· August 2024

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SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial.
Brittany L Ober Shepherd, Paul T Scott, Jack N Hutter, Christine Lee, Melanie D McCauley, Adrian B McDermott

Lancet Microbe· June 2024

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Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody.
Adam S Olia, Madhu Prabhakaran, Darcy R Harris, Crystal Sao-Fong Cheung, Rebecca A Gillespie, Adrian B McDermott

Front Immunol· June 2024

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Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial.
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Adrian B McDermott

PLoS Med· June 2024

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Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria.
Kassoum Kayentao, Aissata Ongoiba, Anne C Preston, Sara A Healy, Zonghui Hu, Adrian B McDermott

N Engl J Med· May 2024

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Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.
Yuhe R Yang, Julianna Han, Hailee R Perrett, Sara T Richey, Alesandra J Rodriguez, Adrian B McDermott

Cell Rep· May 2024

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