Publications by authors named "Adrian Shephard"

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Development and refinement of the sore throat pain model as an assay for measuring therapeutic effects on acute pain.
Bernard P Schachtel, Adrian Shephard

Front Pain Res (Lausanne)· June 2025

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Evidence of the Efficacy of Flurbiprofen 8.75 mg Lozenges for Patients Receiving Antibiotics for Laboratory-Confirmed Streptococcal Pharyngitis.
Bernard Schachtel, Adrian Shephard, Emily Schachtel, Tim Shea, Adam Smith

Ear Nose Throat J· December 2023

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Addressing Consumer Misconceptions on Antibiotic Use and Resistance in the Context of Sore Throat: Learnings from Social Media Listening.
Sabiha Essack, John Bell, Douglas Burgoyne, Khalid Eljaaly, Wirat Tongrod, Adrian Shephard

Antibiotics (Basel)· May 2023

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Efficacy of Triprolidine in the Treatment of Temporary Sleep Disturbance.
Ana Santos Cravo, Adrian Shephard, Tim Shea

J Clin Pharmacol· September 2021

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Point-of-Care Testing for Pharyngitis in the Pharmacy.
Sabiha Essack, John Bell, Douglas Burgoyne, Wirat Tongrod, Martin Duerden, Adrian Shephard

Antibiotics (Basel)· October 2020

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Patients with Sore Throat: A Survey of Self-Management and Healthcare-Seeking Behavior in 13 Countries Worldwide.
Alike W van der Velden, Aurelio Sessa, Attila Altiner, Antonio Carlos Campos Pignatari, Adrian Shephard

Pragmat Obs Res· September 2020

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Inhibition of viral and bacterial trigger-stimulated prostaglandin E by a throat lozenge containing flurbiprofen: An in vitro study using a human respiratory epithelial cell line.
Rob Lambkin-Williams, Alex Mann, Adrian Shephard

SAGE Open Med· September 2020

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Refinement and further application of the Qualities of Sore Throat Index (QuaSTI).
Bernard Schachtel, Adam B Smith, Adrian Shephard

Pain Manag· July 2020

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Letter re: Article by Palm J et al Int J Clin Pract. 2018 Oct 17; 72:e13272.
Adrian Shephard, Anuradha Kulasekaran, Neil Fawkes, Adam Smith, Darren Targett

Int J Clin Pract· February 2020

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Bactericidal activity of hexylresorcinol lozenges against oropharyngeal organisms associated with acute sore throat.
Derek Matthews, Oluwajoba Adegoke, Adrian Shephard

BMC Res Notes· February 2020

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Topical (local) antibiotics for respiratory infections with sore throat: An antibiotic stewardship perspective.
Sabiha Essack, John Bell, Douglas S Burgoyne, Martin Duerden, Adrian Shephard

J Clin Pharm Ther· December 2019

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Locally Delivered Flurbiprofen 8.75 mg for Treatment and Prevention of Sore Throat: A Narrative Review of Clinical Studies.
Ferdinandus de Looze, Adrian Shephard, Adam B Smith

J Pain Res· December 2019

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Onset of analgesia by a topically administered flurbiprofen lozenge: a randomised controlled trial using the double stopwatch method.
Bernard Schachtel, Sue Aspley, Adrian Shephard, Emily Schachtel, Mary Beth Lorton

Br J Pain· November 2018

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Spectrum of bactericidal action of amylmetacresol/2,4-dichlorobenzyl alcohol lozenges against oropharyngeal organisms implicated in pharyngitis.
Derek Matthews, Robert Atkinson, Adrian Shephard

Int J Gen Med· November 2018

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I
Improvements in throat function and qualities of sore throat from locally applied flurbiprofen 8.75 mg in spray or lozenge format: findings from a randomized trial of patients with upper respiratory tract infection in the Russian Federation.
Natalia Burova, Valeria Bychkova, Adrian Shephard

J Pain Res· June 2018

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Comparison of the Characteristics and Performance of Flurbiprofen 8.75 mg Spray for Sore Throat.
David Veale, Adrian Shephard, Verity Adams, Charlotte Lidster

Curr Drug Deliv· May 2018

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Meaningful relief with flurbiprofen 8.75 mg spray in patients with sore throat due to upper respiratory tract infection.
Ferdinandus de Looze, Marc Russo, Mark Bloch, Barney Montgomery, Adrian Shephard

Pain Manag· March 2018

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Q
Qualities of Sore Throat Index (QuaSTI): measuring descriptors of sore throat in a randomized, placebo-controlled trial.
Bernard Schachtel, Adrian Shephard, Emily Schachtel, Mary Beth Lorton, Tim Shea

Pain Manag· March 2018

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Flurbiprofen 8.75 mg lozenges for treating sore throat symptoms: a randomized, double-blind, placebo-controlled study.
Bernard P Schachtel, Adrian Shephard, Timothy Shea, Kathleen Sanner, Laurie Savino

Pain Manag· November 2016

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Efficacy of flurbiprofen 8.75 mg lozenge in patients with a swollen and inflamed sore throat.
Sue Aspley, Adrian Shephard, Emily Schachtel, Kathleen Sanner, Laurie Savino

Curr Med Res Opin· September 2016

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Efficacy of flurbiprofen 8.75 mg spray in patients with sore throat due to an upper respiratory tract infection: A randomised controlled trial.
Ferdinandus de Looze, Marc Russo, Mark Bloch, Barney Montgomery, Adrian Shephard

Eur J Gen Pract· June 2016

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Virucidal action of sore throat lozenges against respiratory viruses parainfluenza type 3 and cytomegalovirus.
Adrian Shephard, Stela Zybeshari

Antiviral Res· November 2015

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Utility of the sore throat pain model in a multiple-dose assessment of the acute analgesic flurbiprofen: a randomized controlled study.
Bernard Schachtel, Sue Aspley, Adrian Shephard, Timothy Shea, Gary Smith

Trials· July 2014

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Onset of action of a lozenge containing flurbiprofen 8.75 mg: a randomized, double-blind, placebo-controlled trial with a new method for measuring onset of analgesic activity.
Bernard Schachtel, Sue Aspley, Adrian Shephard, Timothy Shea, Gary Smith

Pain· February 2014

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Tonic stimulation of the pharyngeal mucosa causes pain and a reversible increase of inflammatory mediators.
Bertold Renner, Gabi Ahne, Elke Grosan, Birgit Kettenmann, Gerd Kobal, Adrian Shephard

Inflamm Res· December 2013

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