Publications by authors named "Adrian Tomkinson"

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Discovery of GS-7682, a Novel 4'-Cyano-Modified -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.
Dustin S Siegel, Hon C Hui, Jared Pitts, Meghan S Vermillion, Kazuya Ishida, Adrian Tomkinson

J Med Chem· August 2024

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Alternating Arenavirus Vector Immunization Generates Robust Polyfunctional Genotype Cross-Reactive Hepatitis B Virus-Specific CD8 T-Cell Responses and High Anti-Hepatitis B Surface Antigen Titers.
Sarah Schmidt, Meron Mengistu, Stephane Daffis, Sarah Ahmadi-Erber, Daniela Deutschmann, Adrian Tomkinson

J Infect Dis· April 2024

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Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection.
Meghan S Vermillion, Eisuke Murakami, Bin Ma, Jared Pitts, Adrian Tomkinson

Sci Transl Med· February 2022

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Discovery of an Atropisomeric PI3Kβ Selective Inhibitor through Optimization of the Hinge Binding Motif.
Stephane Perreault, Fatima Arjmand, Jayaraman Chandrasekhar, Jia Hao, Kathleen S Keegan, Adrian Tomkinson

ACS Med Chem Lett· June 2020

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IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist.
Rebecca E Slager, Gregory A Hawkins, Elizabeth J Ampleford, Alexandra Bowden, Lauren E Stevens, Adrian Tomkinson

J Allergy Clin Immunol· October 2010

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Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats.
Christopher J Parsons, Blair U Bradford, Clark Q Pan, Ellen Cheung, Michael Schauer, Adrian Tomkinson

Hepatology· November 2004

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Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challenge.
Catherine Duez, Azzeddine Dakhama, Adrian Tomkinson, Philippe Marquillies, Annette Balhorn

J Allergy Clin Immunol· October 2004

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Treatment of experimental asthma by long-term gene therapy directed against IL-4 and IL-13.
Tatiana Zavorotinskaya, Adrian Tomkinson, John E Murphy

Mol Ther· February 2003

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Adoptive transfer of T cells induces airway hyperresponsiveness independently of airway eosinophilia but in a signal transducer and activator of transcription 6-dependent manner.
Adrian Tomkinson, Catherine Duez, Michael Lahn, Erwin W Gelfand

J Allergy Clin Immunol· May 2002

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