Publications by authors named "Adrie Jones"

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Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors.
Mary Ellen Molloy, Richard J Austin, Bryan D Lemon, Wade H Aaron, Vaishnavi Ganti, Adrie Jones, Susan D Jones

Clin Cancer Res· March 2021

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TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid Tumors.
Richard J Austin, Bryan D Lemon, Wade H Aaron, Manasi Barath, Patricia A Culp, Adrie Jones

Mol Cancer Ther· January 2021

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Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.
Gwenaella Rescourio, Ana Z Gonzalez, Salman Jabri, Brian Belmontes, Gordon Moody, Adrie Jones

J Med Chem· November 2019

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Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility.
Robert M Rzasa, Michael J Frohn, Kristin L Andrews, Samer Chmait, Ning Chen, Adrie D Jones

Bioorg Med Chem· December 2014

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MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways.
Anne Y Saiki, Sean Caenepeel, Dongyin Yu, Julie A Lofgren, Tao Osgood, Adrie Jones

Oncotarget· April 2014

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Discovery of selective biaryl ethers as PDE10A inhibitors: improvement in potency and mitigation of Pgp-mediated efflux.
Robert M Rzasa, Essa Hu, Shannon Rumfelt, Ning Chen, Kristin L Andrews, Adrie D Jones

Bioorg Med Chem Lett· December 2012

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A homogeneous enzyme fragment complementation-based beta-arrestin translocation assay for high-throughput screening of G-protein-coupled receptors.
Xiaoning Zhao, Adrie Jones, Keith R Olson, Kun Peng, Tom Wehrman

J Biomol Screen· September 2008

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