Publications by authors named "Adwait A Godbole"

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Distinct S-adenosylmethionine synthases link phosphatidylcholine to mitochondrial function and stress survival.
Athena L Munden, Arjamand Mushtaq, Dominique S Lui, Katherine M Edwards, Daniel P Higgins, Adwait A Godbole

PLoS Biol· December 2025

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Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival.
Athena L Munden, Dominique S Lui, Daniel P Higgins, Matthew J Fanelli, Thien-Kim Ngyuen, Adwait A Godbole

bioRxiv· February 2025

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S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress.
Adwait A Godbole, Sneha Gopalan, Thien-Kim Nguyen, Alexander L Munden, Dominique S Lui

Elife· February 2023

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A new DNA sensor system for specific and quantitative detection of mycobacteria.
Oskar Franch, Xiao Han, Lærke Bay Marcussen, Asger Givskov, Marie Bech Andersen, Adwait Anand Godbole

Nanoscale· January 2019

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Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine.
Wei Ding, Daniel P Higgins, Dilip K Yadav, Adwait A Godbole, Read Pukkila-Worley

PLoS Genet· November 2018

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The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Giorgia Mori, Beatrice Silvia Orena, Clara Franch, Lesley A Mitchenall, Adwait Anand Godbole

Tuberculosis (Edinb)· September 2018

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DNA topoisomerase I and DNA gyrase as targets for TB therapy.
Valakunja Nagaraja, Adwait A Godbole, Sara R Henderson, Anthony Maxwell

Drug Discov Today· March 2017

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Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I.
Sean Ekins, Adwait Anand Godbole, György Kéri, Lászlo Orfi, János Pato

Tuberculosis (Edinb)· March 2017

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Transcriptional regulation of topology modulators and transcription regulators of Mycobacterium tuberculosis.
Soumitra Ghosh, Bhavna Padmanabhan, Adwait Anand Godbole, Priyanka Tare, Wareed Ahmed

Biochem Biophys Res Commun· July 2016

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Specific detection of the cleavage activity of mycobacterial enzymes using a quantum dot based DNA nanosensor.
Morten Leth Jepsen, Charlotte Harmsen, Adwait Anand Godbole, Valakunja Nagaraja, Birgitta R Knudsen

Nanoscale· January 2016

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Lead selection and characterization of antitubercular compounds using the Nested Chemical Library.
Anna Sipos, János Pató, Rita Székely, Ruben C Hartkoorn, László Kékesi, Adwait Anand Godbole

Tuberculosis (Edinb)· June 2015

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Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors.
Adwait Anand Godbole, Wareed Ahmed, Rajeshwari Subray Bhat, Erin K Bradley, Sean Ekins

Antimicrob Agents Chemother· March 2015

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Conditional silencing of topoisomerase I gene of Mycobacterium tuberculosis validates its essentiality for cell survival.
Wareed Ahmed, Shruti Menon, Adwait Anand Godbole, Pullela V D N B Karthik, Valakunja Nagaraja

FEMS Microbiol Lett· April 2014

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Inhibition of Mycobacterium tuberculosis topoisomerase I by m-AMSA, a eukaryotic type II topoisomerase poison.
Adwait Anand Godbole, Wareed Ahmed, Rajeshwari Subray Bhat, Erin K Bradley, Sean Ekins

Biochem Biophys Res Commun· April 2014

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Type IA topoisomerase inhibition by clamp closure.
Majety Naga Leelaram, Anuradha Gopal Bhat, Adwait Anand Godbole, Rajeshwari Subray Bhat, Ramanathapuram Manjunath

FASEB J· August 2013

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Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity.
Adwait Anand Godbole, Majety Naga Leelaram, Anuradha Gopal Bhat, Paras Jain, Valakunja Nagaraja

Arch Biochem Biophys· December 2012

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