Publications by authors named "Janos Pato"

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Targeted drug combination therapy design based on driver genes.
Lilian Zsákai, Anna Sipos, Judit Dobos, Dániel Erős, Csaba Szántai-Kis

Oncotarget· September 2019

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Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH.
Vinayak Singh, Angela Pacitto, Stefano Donini, Davide M Ferraris, Sándor Boros, Janos Pato

Eur J Med Chem· July 2019

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Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I.
Sean Ekins, Adwait Anand Godbole, György Kéri, Lászlo Orfi, János Pato

Tuberculosis (Edinb)· March 2017

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The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.
Vinayak Singh, Stefano Donini, Angela Pacitto, Claudia Sala, Ruben C Hartkoorn, Janos Pato

ACS Infect Dis· January 2017

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Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Vinayak Singh, Neeraj Dhar, János Pató, Gaëlle S Kolly, Jana Korduláková

Mol Microbiol· January 2017

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Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway.
Carolina Lavoz, Matilde Alique, Raquel Rodrigues-Diez, Janos Pato, Gyorgy Keri

J Pathol· August 2015

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Lead selection and characterization of antitubercular compounds using the Nested Chemical Library.
Anna Sipos, János Pató, Rita Székely, Ruben C Hartkoorn, László Kékesi

Tuberculosis (Edinb)· June 2015

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The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells.
Raúl R Rodrigues-Diez, Ana Belen Garcia-Redondo, Macarena Orejudo, Raquel Rodrigues-Diez, Ana Maria Briones, Janos Pato

Antioxid Redox Signal· January 2015

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[Pyrido[2,3-b]pyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines, and their preparation via regioselective condensation reaction].
László Kékesi, Anna Sipos, Gábor Németh, András Dancsó, Eszter Illyés

Acta Pharm Hung· January 2015

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Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion.
Jan Rybniker, Jeffrey M Chen, Claudia Sala, Ruben C Hartkoorn, Anthony Vocat

Cell Host Microbe· October 2014

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[Development and study of structure-activity relationship of drugs against Mycobacterium tuberculosis].
Ferenc Baska, Edina Rita Székely, Csaba Szántai-Kis, Péter Bánhegyi, Bálint Hegymegi-Barakonyi

Acta Pharm Hung· January 2014

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TWEAK transactivation of the epidermal growth factor receptor mediates renal inflammation.
Sandra Rayego-Mateos, Jose Luis Morgado-Pascual, Ana Belen Sanz, Adrian Mario Ramos, Satoru Eguchi, Janos Pato

J Pathol· December 2013

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Synthesis and biological evaluation of novel pyrido[2,3-b]pyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines.
László Kékesi, Anna Sipos, Gábor Németh, János Pató, Nóra Breza

Bioorg Med Chem Lett· November 2013

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Connective tissue growth factor is a new ligand of epidermal growth factor receptor.
Sandra Rayego-Mateos, Raquel Rodrigues-Díez, Jose Luis Morgado-Pascual, Raul R Rodrigues Díez, Sebastian Mas, Janos Pato

J Mol Cell Biol· October 2013

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Development of a cell-selective and intrinsically active multikinase inhibitor bioconjugate.
Stefan Harmsen, M Emmy M Dolman, Zoltan Nemes, Marie Lacombe, Bálint Szokol

Bioconjug Chem· April 2011

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Leads for antitubercular compounds from kinase inhibitor library screens.
Sophie Magnet, Ruben C Hartkoorn, Rita Székely, János Pató, James A Triccas

Tuberculosis (Edinb)· November 2010

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Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases.
Nora Breza, Janos Pato, Laszlo Orfi, Balint Hegymegi-Barakonyi, Peter Banhegyi

J Recept Signal Transduct Res· January 2009

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Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors.
Marjan M Fretz, M E Emmy M Dolman, Marie Lacombe, Jai Prakash, Tri Q Nguyen, Janos Pato

J Control Release· December 2008

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A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling.
Rita Székely, Frigyes Wáczek, István Szabadkai, Gábor Németh, Bálint Hegymegi-Barakonyi

Immunol Lett· March 2008

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[Synthesis of thiophene and alpha-terthiophene derivatives with antiproliferative activity].
Zsolt Székelyhidi, János Pató, Bálint Hegymegi-Barakonyi, Péter Bánhegyi, György Mészáros

Acta Pharm Hung· August 2006

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Drug discovery in the kinase inhibitory field using the Nested Chemical Library technology.
György Kéri, Zsolt Székelyhidi, Péter Bánhegyi, Zoltán Varga, Bálint Hegymegi-Barakonyi

Assay Drug Dev Technol· October 2005

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Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.
Zsolt Székelyhidi, János Pató, Frigyes Wáczek, Péter Bánhegyi, Bálint Hegymegi-Barakonyi

Bioorg Med Chem Lett· July 2005

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Improved, high yield synthesis of 3H-quinazolin-4-ones, the key intermediates of recently developed drugs.
László Orfi, Frigyes Wáczek, János Pató, István Varga, Bálint Hegymegi-Barakonyi

Curr Med Chem· October 2004

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