Publications by authors named "Aeron Small"

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Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.
Aeron M Small, Ta-Yu Yang, Shinsuke Itoh, Sébastien Thériault, Line Dufresne

Nat Genet· December 2025

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A Deep Learning Model to Identify Mitral Valve Prolapse From the Echocardiogram.
Mostafa A Al-Alusi, Emily S Lau, Aeron M Small, Christopher Reeder, Tal Shnitzer

JACC Cardiovasc Imaging· September 2025

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Managing Cardiovascular Risk in Clonal Hematopoiesis of Indeterminate Potential: JACC: CardioOncology Short-Form Primer.
Ohad Oren, Aeron M Small, Amy E Lin, Peter Libby

JACC CardioOncol· August 2025

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Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease.
Teresa Trenkwalder, Carlo Maj, Baravan Al-Kassou, Radoslaw Debiec, Stefanie A Doppler, Aeron M Small

JAMA Cardiol· February 2025

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Longitudinal Evaluation of Genetic Hypertrophic Cardiomyopathy Penetrance and Transition to Disease in an Academic Biobank.
Joseph Y Shin, Aeron M Small, Carrie L Blout Zawatsky, Michael A Fifer, Albree Tower-Rader

JACC Adv· February 2025

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Clonal Hematopoiesis of Indeterminate Potential.
Peter Libby, Ohad Oren, Aeron M Small

JAMA Cardiol· January 2025

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Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction.
Art Schuermans, Ashley B Pournamdari, Jiwoo Lee, Rohan Bhukar, Shriienidhie Ganesh, Aeron M Small

Nat Cardiovasc Res· December 2024

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Association of Lipoprotein(a) With Major Adverse Cardiovascular Events Across hs-CRP: A Systematic Review and Meta-Analysis.
Pamela L Alebna, Chin Yip Han, Mathew Ambrosio, Gwyneth Kong, John W Cyrus, Aeron M Small

JACC Adv· December 2024

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Clonal hematopoiesis and atherosclerosis.
Ohad Oren, Aeron M Small, Peter Libby

J Clin Invest· October 2024

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Unraveling the Mechanisms of Valvular Heart Disease to Identify Medical Therapy Targets: A Scientific Statement From the American Heart Association.
Aeron M Small, Katherine E Yutzey, Bryce A Binstadt, Kaitlin Voigts Key, Nabila Bouatia-Naji

Circulation· August 2024

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Plasma Proteomic Biomarkers of Aortic Stenosis: A Mendelian Randomization Study.
Ta-Yu Yang, Aeron M Small, Line Dufresne, Gina M Peloso, Pradeep Natarajan

J Am Coll Cardiol· August 2024

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Lipoprotein(a), C-Reactive Protein, and Cardiovascular Risk in Primary and Secondary Prevention Populations.
Aeron M Small, Ashley Pournamdari, Giorgio E M Melloni, Benjamin M Scirica, Deepak L Bhatt

JAMA Cardiol· April 2024

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Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis.
Aeron M Small, Giorgio E M Melloni, Frederick K Kamanu, Brian A Bergmark, Marc P Bonaca

JAMA Cardiol· April 2024

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Genetic Associations of Circulating Cardiovascular Proteins With Gestational Hypertension and Preeclampsia.
Art Schuermans, Buu Truong, Maddalena Ardissino, Rohan Bhukar, Eric A W Slob, Aeron M Small

JAMA Cardiol· March 2024

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Lipoprotein(a) Concentrations Are Independent of Polygenic Score for Coronary Artery Disease.
Michael N Trinh, Ashley Pournamdari, Aeron M Small, Gina M Peloso, Aniruddh P Patel

JACC Adv· February 2024

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Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease.
Maximillian A Rogers, Francesca Bartoli-Leonard, Kang H Zheng, Aeron M Small, Hao Yu Chen

Circulation· January 2024

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Integrative proteomic analyses across common cardiac diseases yield new mechanistic insights and enhanced prediction.
Art Schuermans, Ashley B Pournamdari, Jiwoo Lee, Rohan Bhukar, Shriienidhie Ganesh, Aeron M Small

medRxiv· December 2023

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Why Y? The Y chromosome may serve a cardiovascular purpose after all.
Aeron M Small, Peter Libby

Eur Heart J· June 2023

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Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.
Hao Yu Chen, Christian Dina, Aeron M Small, Christian M Shaffer, Rebecca T Levinson

Eur Heart J· June 2023

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Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program.
Aeron M Small, Gina M Peloso, Jason Linefsky, Jayashri Aragam, Ashley Galloway

Circulation· March 2023

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Plasma biomarkers associated with adverse outcomes in patients with calcific aortic stenosis.
Mahesh K Vidula, Alena Orlenko, Lei Zhao, Lisa Salvador, Aeron M Small

Eur J Heart Fail· December 2021

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The impact of removing former drinkers from genome-wide association studies of AUDIT-C.
Cecilia Dao, Hang Zhou, Aeron Small, Kirsha S Gordon, Boyang Li

Addiction· November 2021

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Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease-Brief Report.
Aeron M Small, Jennifer E Huffman, Derek Klarin, Maria Sabater-Lleal, Julie A Lynch

Arterioscler Thromb Vasc Biol· January 2021

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PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.
Aeron M Small, Jennifer E Huffman, Derek Klarin, Julie A Lynch, Themistocles Assimes

PLoS One· January 2021

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Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways.
Archna Bajaj, Andrea Ihegword, Chengxiang Qiu, Aeron M Small, Wei-Qi Wei

Kidney Int· May 2020

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