Publications by authors named "Aicha Demidem"

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PLD2 is a marker for MASLD-HCC with early-stage fibrosis: revealed by lipidomic and gene expression analysis.
Jihan Sun, Fatima Dahboul, Estelle Pujos-Guillot, Mélanie Petera, Emeline Chu-Van, Aicha Demidem

Metabolomics· March 2025

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Simultaneous Activation of Beta-Oxidation and De Novo Lipogenesis in MASLD-HCC: A New Paradigm.
Fatima Dahboul, Jihan Sun, Benjamin Buchard, Natali Abeywickrama-Samarakoon, Estelle Pujos-Guillot, Aicha Demidem

Liver Int· February 2025

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Plasma Metabolomics for Discovery of Early Metabolic Markers of Prostate Cancer Based on Ultra-High-Performance Liquid Chromatography-High Resolution Mass Spectrometry.
Xiangping Lin, Lucie Lécuyer, Xinyu Liu, Mohamed N Triba, Mélanie Deschasaux-Tanguy, Aïcha Demidem

Cancers (Basel)· June 2021

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NMR metabolomic profiles associated with long-term risk of prostate cancer.
Lucie Lécuyer, Agnès Victor Bala, Aicha Demidem, Adrien Rossary, Nadia Bouchemal

Metabolomics· March 2021

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Two Metabolomics Phenotypes of Human Hepatocellular Carcinoma in Non-Alcoholic Fatty Liver Disease According to Fibrosis Severity.
Benjamin Buchard, Camille Teilhet, Natali Abeywickrama Samarakoon, Sylvie Massoulier, Juliette Joubert-Zakeyh, Aicha Demidem

Metabolites· January 2021

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Untargeted plasma metabolomic profiles associated with overall diet in women from the SU.VI.MAX cohort.
Lucie Lécuyer, Céline Dalle, Pierre Micheau, Mélanie Pétéra, Delphine Centeno, Aicha Demidem

Eur J Nutr· December 2020

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Diet-Related Metabolomic Signature of Long-Term Breast Cancer Risk Using Penalized Regression: An Exploratory Study in the SU.VI.MAX Cohort.
Lucie Lécuyer, Céline Dalle, Sophie Lefevre-Arbogast, Pierre Micheau, Bernard Lyan, Aicha Demidem

Cancer Epidemiol Biomarkers Prev· February 2020

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Plasma Metabolomic Signatures Associated with Long-term Breast Cancer Risk in the SU.VI.MAX Prospective Cohort.
Lucie Lécuyer, Céline Dalle, Bernard Lyan, Aicha Demidem, Adrien Rossary

Cancer Epidemiol Biomarkers Prev· August 2019

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NMR metabolomic signatures reveal predictive plasma metabolites associated with long-term risk of developing breast cancer.
Lucie Lécuyer, Agnès Victor Bala, Mélanie Deschasaux, Nadia Bouchemal, Mohamed Nawfal Triba, Aicha Demidem

Int J Epidemiol· April 2018

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NMR metabolomics of fibroblasts with inherited mitochondrial Complex I mutation reveals treatment-reversible lipid and amino acid metabolism alterations.
Daniel Morvan, Aicha Demidem

Metabolomics· March 2018

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Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts ¹H-NMR Spectroscopy.
Camille Teilhet, Daniel Morvan, Juliette Joubert-Zakeyh, Anne-Sophie Biesse, Bruno Pereira, Aicha Demidem

Metabolites· September 2017

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Metabolomics and transcriptomics demonstrate severe oxidative stress in both localized chemotherapy-treated and bystander tumors.
Daniel Morvan, Aicha Demidem

Biochim Biophys Acta· March 2014

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Normal human melanocytes exposed to chronic insulin and glucose supplementation undergo oncogenic changes and methyl group metabolism cellular redistribution.
Daniel Morvan, Jean Marc Steyaert, Laurent Schwartz, Maurice Israel, Aicha Demidem

Am J Physiol Endocrinol Metab· June 2012

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Cell cycle-dependent conjugation of endogenous BRCA1 protein with SUMO-2/3.
Aurélie Vialter, Anne Vincent, Aïcha Demidem, Daniel Morvan, Georges Stepien

Biochim Biophys Acta· April 2011

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Quantitative two-dimensional HRMAS 1H-NMR spectroscopy-based metabolite profiling of human cancer cell lines and response to chemotherapy.
Mathilde Bayet-Robert, Dominique Loiseau, Pascale Rio, Aicha Demidem, Chantal Barthomeuf

Magn Reson Med· May 2010

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A model of phospholipid biosynthesis in tumor in response to an anticancer agent in vivo.
Mahsa Behzadi, Aicha Demidem, Daniel Morvan, Laurent Schwartz, Georges Stepien

J Integr Bioinform· March 2010

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Combined methionine deprivation and chloroethylnitrosourea have time-dependent therapeutic synergy on melanoma tumors that NMR spectroscopy-based metabolomics explains by methionine and phospholipid metabolism reprogramming.
Samuel Guénin, Daniel Morvan, Emilie Thivat, Georges Stepien, Aicha Demidem

Nutr Cancer· November 2009

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Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy.
Dominique Loiseau, Daniel Morvan, Arnaud Chevrollier, Aicha Demidem, Olivier Douay

Mol Carcinog· August 2009

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Optimal methionine-free diet duration for nitrourea treatment: a Phase I clinical trial.
Xavier Durando, Emilie Thivat, Marie-Chantal Farges, Eric Cellarier, Michel D'Incan, Aïcha Demidem

Nutr Cancer· May 2008

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Chemotherapy-induced bystander effect in response to several chloroethylnitrosoureas: an origin independent of DNA damage?
Patrick Merle, Daniel Morvan, Denis Caillaud, Aicha Demidem

Anticancer Res· April 2008

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PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: a mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment.
Samuel Guénin, Laurent Schwartz, Daniel Morvan, Jean Marc Steyaert, Amandine Poignet, Aicha Demidem

Int J Oncol· January 2008

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A methionine-free diet associated with nitrosourea treatment down-regulates methylguanine-DNA methyl transferase activity in patients with metastatic cancer.
Emilie Thivat, Xavier Durando, Aïcha Demidem, Marie-Chantal Farges, Maryse Rapp

Anticancer Res· August 2007

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Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloroethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways.
Daniel Morvan, Aicha Demidem

Cancer Res· March 2007

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CENU treatment induced bystander effects which are effective on parental and non-parental tumors and have a phospholipid metabolism proton NMR spectroscopy signature.
Patrick Merle, Daniel Morvan, Jean Claude Madelmont, Denis Caillaud, Aicha Demidem

Int J Oncol· September 2006

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Methionine-dependence phenotype of tumors: metabolite profiling in a melanoma model using L-[methyl-13C]methionine and high-resolution magic angle spinning 1H-13C nuclear magnetic resonance spectroscopy.
Daniel Morvan, Aicha Demidem, Samuel Guenin, Jean Claude Madelmont

Magn Reson Med· May 2006

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