Publications by authors named "Daniel Morvan"

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Joint Metabolomics and Transcriptomics Reveal Rewired Glycerophospholipid and Arginine Metabolism as Components of BRCA1-Induced Metabolic Reprogramming in Breast Cancer Cells.
Thomas Lucaora, Daniel Morvan

Metabolites· August 2025

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Untargeted 2D NMR Metabolomics of [C-]Methionine-Labeled Tumor Models Reveals the Non-DNA Methylome and Provides Clues to Methyl Metabolism Shift during Tumor Progression.
Daniel Morvan, Florent Cachin

J Proteome Res· April 2022

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NMR metabolomics of fibroblasts with inherited mitochondrial Complex I mutation reveals treatment-reversible lipid and amino acid metabolism alterations.
Daniel Morvan, Aicha Demidem

Metabolomics· March 2018

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Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts ¹H-NMR Spectroscopy.
Camille Teilhet, Daniel Morvan, Juliette Joubert-Zakeyh, Anne-Sophie Biesse, Bruno Pereira

Metabolites· September 2017

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BRCA1 induces major energetic metabolism reprogramming in breast cancer cells.
Maud Privat, Nina Radosevic-Robin, Corinne Aubel, Anne Cayre, Frédérique Penault-Llorca, Daniel Morvan

PLoS One· November 2015

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Metabolomics and transcriptomics demonstrate severe oxidative stress in both localized chemotherapy-treated and bystander tumors.
Daniel Morvan, Aicha Demidem

Biochim Biophys Acta· March 2014

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Metabolomics reveals metabolic targets and biphasic responses in breast cancer cells treated by curcumin alone and in association with docetaxel.
Mathilde Bayet-Robert, Daniel Morvan

PLoS One· December 2013

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Functional metabolomics uncovers metabolic alterations associated to severe oxidative stress in MCF7 breast cancer cells exposed to ascididemin.
Daniel Morvan

Mar Drugs· October 2013

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Normal human melanocytes exposed to chronic insulin and glucose supplementation undergo oncogenic changes and methyl group metabolism cellular redistribution.
Daniel Morvan, Jean Marc Steyaert, Laurent Schwartz, Maurice Israel, Aicha Demidem

Am J Physiol Endocrinol Metab· June 2012

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Cell cycle-dependent conjugation of endogenous BRCA1 protein with SUMO-2/3.
Aurélie Vialter, Anne Vincent, Aïcha Demidem, Daniel Morvan, Georges Stepien

Biochim Biophys Acta· April 2011

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Biochemical disorders induced by cytotoxic marine natural products in breast cancer cells as revealed by proton NMR spectroscopy-based metabolomics.
Mathilde Bayet-Robert, Suzanne Lim, Chantal Barthomeuf, Daniel Morvan

Biochem Pharmacol· October 2010

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Quantitative two-dimensional HRMAS 1H-NMR spectroscopy-based metabolite profiling of human cancer cell lines and response to chemotherapy.
Mathilde Bayet-Robert, Dominique Loiseau, Pascale Rio, Aicha Demidem, Chantal Barthomeuf, Daniel Morvan

Magn Reson Med· May 2010

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Pharmacometabolomics of docetaxel-treated human MCF7 breast cancer cells provides evidence of varying cellular responses at high and low doses.
Mathilde Bayet-Robert, Daniel Morvan, Philippe Chollet, Chantal Barthomeuf

Breast Cancer Res Treat· April 2010

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A model of phospholipid biosynthesis in tumor in response to an anticancer agent in vivo.
Mahsa Behzadi, Aicha Demidem, Daniel Morvan, Laurent Schwartz, Georges Stepien

J Integr Bioinform· March 2010

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Combined methionine deprivation and chloroethylnitrosourea have time-dependent therapeutic synergy on melanoma tumors that NMR spectroscopy-based metabolomics explains by methionine and phospholipid metabolism reprogramming.
Samuel Guénin, Daniel Morvan, Emilie Thivat, Georges Stepien, Aicha Demidem

Nutr Cancer· November 2009

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Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy.
Dominique Loiseau, Daniel Morvan, Arnaud Chevrollier, Aicha Demidem, Olivier Douay

Mol Carcinog· August 2009

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Chemotherapy-induced bystander effect in response to several chloroethylnitrosoureas: an origin independent of DNA damage?
Patrick Merle, Daniel Morvan, Denis Caillaud, Aicha Demidem

Anticancer Res· April 2008

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PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: a mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment.
Samuel Guénin, Laurent Schwartz, Daniel Morvan, Jean Marc Steyaert, Amandine Poignet

Int J Oncol· January 2008

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Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloroethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways.
Daniel Morvan, Aicha Demidem

Cancer Res· March 2007

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Bystander effects are induced by CENU treatment and associated with altered protein secretory activity of treated tumor cells: a relay for chemotherapy?
Aicha Demidem, Daniel Morvan, Jean Claude Madelmont

Int J Cancer· September 2006

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CENU treatment induced bystander effects which are effective on parental and non-parental tumors and have a phospholipid metabolism proton NMR spectroscopy signature.
Patrick Merle, Daniel Morvan, Jean Claude Madelmont, Denis Caillaud, Aicha Demidem

Int J Oncol· September 2006

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Methionine-dependence phenotype of tumors: metabolite profiling in a melanoma model using L-[methyl-13C]methionine and high-resolution magic angle spinning 1H-13C nuclear magnetic resonance spectroscopy.
Daniel Morvan, Aicha Demidem, Samuel Guenin, Jean Claude Madelmont

Magn Reson Med· May 2006

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Response of melanoma tumor phospholipid metabolism to chloroethyle nitrosourea: a high resolution proton NMR spectroscopy study.
Daniel Morvan, Aïcha Demidem, Jean-Claude Madelmont

Pathol Biol (Paris)· July 2003

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Quantitative HRMAS proton total correlation spectroscopy applied to cultured melanoma cells treated by chloroethyl nitrosourea: demonstration of phospholipid metabolism alterations.
Daniel Morvan, Aicha Demidem, Janine Papon, Jean Claude Madelmont

Magn Reson Med· February 2003

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Melanoma tumors acquire a new phospholipid metabolism phenotype under cystemustine as revealed by high-resolution magic angle spinning proton nuclear magnetic resonance spectroscopy of intact tumor samples.
Daniel Morvan, Aicha Demidem, Janine Papon, Monique De Latour, Jean Claude Madelmont

Cancer Res· March 2002

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