Publications by authors named "Aida Delgado"

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Allosteric Modulation of GCase Enhances Lysosomal Activity and Reduces ER Stress in GCase-Related Disorders.
Ilaria Fregno, Natalia Pérez-Carmona, Mikhail Rudinskiy, Tatiana Soldà, Timothy J Bergmann, Aida Delgado

Int J Mol Sci· May 2025

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A novel allosteric GCase modulator prevents Tau accumulation in GBA1 and GBA1 cellular models.
Matteo Ciccaldo, Natàlia Pérez-Carmona, Ester Piovesana, Sara Cano-Crespo, Ana Ruano, Aida Delgado

Sci Rep· May 2025

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Developing Allosteric Chaperones for -Associated Disorders-An Integrated Computational and Experimental Approach.
Marta Montpeyo, Natàlia Pérez-Carmona, Elena Cubero, Aida Delgado, Ana Ruano

Int J Mol Sci· December 2024

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Use of the Novel Site-Directed Enzyme Enhancement Therapy (SEE-Tx) Drug Discovery Platform to Identify Pharmacological Chaperones for Glutaric Acidemia Type 1.
Madalena Barroso, Alexandra Puchwein-Schwepcke, Lars Buettner, Ingrid Goebel, Katrin Küchler, Aida Delgado

J Med Chem· October 2024

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Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I.
Elena Cubero, Ana Ruano, Aida Delgado, Xavier Barril, Sara Morales

PLoS One· May 2024

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Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors.
Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann, Aida Delgado

PLoS One· December 2023

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Synthesis, biological evaluation and SAR studies of novel bicyclic antitumor platinum(IV) complexes.
Julia Lorenzo, Aida Delgado, Ángel M Montaña, Juan M Mesas, María-Teresa Alegre

Eur J Med Chem· August 2014

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