Publications by authors named "Ailing Xue"

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A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
Dominik Saul, Robyn Laura Kosinsky, Elizabeth J Atkinson, Madison L Doolittle, Xu Zhang, Nathan K LeBrasseur, Robert J Pignolo, Paul D Robbins, Laura J Niedernhofer, Yuji Ikeno

Nat Commun· August 2022

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Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
Yi Zhu, Larissa G P Langhi Prata, Erin O Wissler Gerdes, Jair Machado Espindola Netto, Tamar Pirtskhalava, Nino Giorgadze, Utkarsh Tripathi, Christina L Inman, Kurt O Johnson, Ailing Xue

March 2022

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Renal Ischemia Induces Endoplasmic Reticulum Stress and Impairs the Reparative Potency of Scattered Tubular-Like Cells.
Alfonso Eirin, Sara Kazeminia, Barnit Kaur, Kumar Shivam, Xiang-Yang Zhu, Ailing Xue

Am J Nephrol· October 2025

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Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease.
Valentina R Garbarino, Juan Pablo Palavicini, Justin Melendez, Nicolas R Barthelemy, Yingxin He, Ailing Xue

Neurotherapeutics· July 2025

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Immune rejection of human mesenchymal stem cells compared to extracellular vesicles in mice with renal artery stenosis.
Tarek Ziad Arabi, Yazan Almasry, Ailing Xue, Alfonso Eirin, Amir Lerman

Stem Cells Transl Med· April 2025

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Renovascular Disease and Mitochondrial Dysfunction in Human Mesenchymal Stem Cells.
Alfonso Eirin, Sarosh Siddiqi, Autumn G Hughes, Yamei Jiang, Xiang-Yang Zhu, Ailing Xue

J Am Soc Nephrol· November 2024

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Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden.
Moritz Weigl, Teresa L Krammer, Marianne Pultar, Matthias Wieser, Selim Chaib, Ailing Xue

bioRxiv· April 2024

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Evaluation of Exploratory Fluid Biomarker Results from a Phase 1 Senolytic Trial in Mild Alzheimer's Disease.
Valentina R Garbarino, Juan Pablo Palavicini, Justin Melendez, Nicolas Barthelemy, Yingxin He, Ailing Xue

Res Sq· March 2024

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SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3.
Utkarsh Tripathi, Rayhane Nchioua, Larissa G P Langhi Prata, Yi Zhu, Erin O Wissler Gerdes, Ailing Xue

Aging (Albany NY)· September 2021

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Senolytics reduce coronavirus-related mortality in old mice.
Christina D Camell, Matthew J Yousefzadeh, Yi Zhu, Larissa G P Langhi Prata, Matthew A Huggins, Ailing Xue

Science· July 2021

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Corrigendum to 'Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Ailing Xue

EBioMedicine· February 2020

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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Ailing Xue

EBioMedicine· September 2019

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Thrombin generation profiles as predictors of symptomatic venous thromboembolism after trauma: A prospective cohort study.
Myung S Park, Grant M Spears, Kent R Bailey, Ailing Xue, Michael J Ferrara

J Trauma Acute Care Surg· September 2017

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Thrombin generation and procoagulant microparticle profiles after acute trauma: A prospective cohort study.
Myung S Park, Ailing Xue, Grant M Spears, Timothy M Halling, Michael J Ferrara

J Trauma Acute Care Surg· November 2015

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Mechanisms of intrinsic force in small human airways.
Mark E Wylam, Ailing Xue, Gary C Sieck

Respir Physiol Neurobiol· April 2012

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Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells.
Eva M Carmona, Jeffrey D Lamont, Ailing Xue, Mark Wylam, Andrew H Limper

Respir Res· July 2010

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Distribution of major basic protein on human airway following in vitro eosinophil incubation.
Ailing Xue, John Wang, Gary C Sieck, Mark E Wylam

Mediators Inflamm· June 2010

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Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes.
Thomas A White, Ailing Xue, Eduardo N Chini, Michael Thompson, Gary C Sieck

Am J Respir Cell Mol Biol· August 2006

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HLA-DQ8 is a predisposing molecule for detergent enzyme subtilisin BPN'-induced hypersensitivity.
Ailing Xue, Svetlana P Chapoval, Elizabeth S Finn, Vaidehi R Chowdhary, Eric V Marietta

Clin Immunol· December 2005

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Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers.
Yuning Xiong, Sean C Dowdy, Ailing Xue, Jiang Shujuan, Norman L Eberhardt

Gynecol Oncol· March 2005

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