Publications by authors named "Aizhi Zhao"

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Antibody-drug conjugates targeting CD248 inhibits liver fibrosis through specific killing on myofibroblasts.
Shaojie Liu, Donghui Han, Chao Xu, Fa Yang, Yu Li, Xiaolong Zhao, Aizhi Zhao

Mol Med· March 2022

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Antibody-drug conjugates targeting CD248 myofibroblasts effectively alleviate renal fibrosis in mice.
Chao Xu, Shaojie Liu, Fa Yang, Keying Zhang, Yu Li, Xiaolong Zhao, Aizhi Zhao

FASEB J· February 2022

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Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma.
Fa Yang, Yan Wei, Donghui Han, Yu Li, Shengjia Shi, Aizhi Zhao

Cancer Res· September 2020

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Therapeutic effects of human monoclonal PSMA antibody-mediated TRIM24 siRNA delivery in PSMA-positive castration-resistant prostate cancer.
Sheng-Jia Shi, Li-Juan Wang, Dong-Hui Han, Jie-Heng Wu, Dian Jiao, Ai-Zhi Zhao

Theranostics· January 2020

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Simple strategy for single-chain fragment antibody-conjugated probe construction.
Chen Xu, Xiang Chen, Mingjuan Yang, Xiaopeng Yuan, Aizhi Zhao

Life Sci· December 2019

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A Novel Fully Human Antibody targeting Extracellular Domain of PSMA Inhibits Tumor Growth in Prostate Cancer.
Jieheng Wu, Donghui Han, Shengjia Shi, Qiang Zhang, Guoxu Zheng, Aizhi Zhao

Mol Cancer Ther· July 2019

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Expression of Prostate-Specific Membrane Antigen in Tumor-Associated Vasculature Predicts Poor Prognosis in Hepatocellular Carcinoma.
Dian Jiao, Yu Li, Fa Yang, Donghui Han, Jieheng Wu, Aizhi Zhao

Clin Transl Gastroenterol· May 2019

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Xihuang Pill Induces Apoptosis of Human Glioblastoma U-87 MG Cells via Targeting ROS-Mediated Akt/mTOR/FOXO1 Pathway.
Meng Shao, Zhenqiang He, Zhixin Yin, Peihong Ma, Qian Xiao, Aizhi Zhao

Evid Based Complement Alternat Med· June 2018

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A fusion-protein approach enabling mammalian cell production of tumor targeting protein domains for therapeutic development.
Jia Hu, Xiang Chen, Xuhua Zhang, Xiaopeng Yuan, Mingjuan Yang, Aizhi Zhao

Protein Sci· May 2018

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Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.
Xiaopeng Yuan, Mingjuan Yang, Xiang Chen, Xuhua Zhang, Shrey Sukhadia, Aizhi Zhao

Cancer Immunol Immunother· February 2018

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Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.
Xiaopeng Yuan, Mingjuan Yang, Xiang Chen, Xuhua Zhang, Shrey Sukhadia, Aizhi Zhao

Cancer Immunol Immunother· March 2017

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Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy.
Aizhi Zhao, Mohammad R Tohidkia, Donald L Siegel, George Coukos, Yadollah Omidi

Crit Rev Biotechnol· October 2016

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A novel anti-PSMA human scFv has the potential to be used as a diagnostic tool in prostate cancer.
Donghui Han, Jieheng Wu, Yueheng Han, Ming Wei, Sen Han, Aizhi Zhao

Oncotarget· September 2016

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Efficient construct of a large and functional scFv yeast display library derived from the ascites B cells of ovarian cancer patients by three-fragment transformation-associated recombination.
Xiaopeng Yuan, Xiang Chen, Mingjuan Yang, Jia Hu, Wei Yang, Aizhi Zhao

Appl Microbiol Biotechnol· May 2016

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Preclinical safety evaluation of recombinant adeno-associated virus 2 vector encoding human tumor necrosis factor receptor-immunoglobulin Fc fusion gene.
Xiaobing Zhou, Lianzhong Shen, Li Liu, Chao Wang, Weihong Qi, Aizhi Zhao

Hum Vaccin Immunother· March 2016

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Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer.
Chunsheng Li, Junying Wang, Jia Hu, Yi Feng, Kosei Hasegawa, Aizhi Zhao

Oncotarget· August 2014

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Novel recombinant human b7-h4 antibodies overcome tumoral immune escape to potentiate T-cell antitumor responses.
Denarda Dangaj, Evripidis Lanitis, Aizhi Zhao, Shree Joshi, Yi Cheng

Cancer Res· August 2013

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Modulation of immune and inflammatory responses on experimental arthritis following intraarticular gene transfer of tumor necrosis factor receptor-immunoglobulin Fc.
Xiaobing Zhou, Kai Gao, Lianzhong Shen, Aizhi Zhao, Xiaobing Wu

Rheumatol Int· September 2012

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Mannose receptor (MR) engagement by mesothelin GPI anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody.
Denarda Dangaj, Karen L Abbott, Ananda Mookerjee, Aizhi Zhao, Pamela S Kirby

PLoS One· July 2012

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Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
Weizhong Zhu, Natalia Petrashevskaya, Shuxun Ren, Aizhi Zhao, Khalid Chakir

Circ Res· January 2012

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Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/TEM1, using a paired yeast-display/secretory scFv library platform.
Aizhi Zhao, Selene Nunez-Cruz, Chunsheng Li, George Coukos, Don L Siegel

J Immunol Methods· January 2011

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T-vector and in vivo recombination as tools to construct a large antibody library of breast cancer.
Yong-Gang Lv, Ting Wang, Shi-Fang Yuan, Nan-Lin Li, Jiang-Hao Chen, Ai-Zhi Zhao

Hybridoma (Larchmt)· June 2010

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A novel technique for efficient construction of large scFv libraries.
Weijun Qin, Aizhi Zhao, Yueheng Han, Weihong Wen, Yu Li

Mol Biotechnol· November 2007

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Isolation and identification of an scFv antibody against nucleocapsid protein of SARS-CoV.
Aizhi Zhao, Weijun Qin, Yueheng Han, Weihong Wen, Wenhong Zhang

Microbes Infect· July 2007

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[Expression, purification and activity analysis of human single-chain antibody against hepatocellular cancer].
Qing-tao Zhao, Long-yang Ma, Guo-zhu Xue, Ai-zhi Zhao, Ke-feng Dou

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi· July 2007

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