Publications by authors named "Akimasa Hayashi"

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Transcriptomic Plasticity is a Hallmark of Metastatic Pancreatic Cancer.
Alejandro Jiménez-Sánchez, Sitara Persad, Akimasa Hayashi, Shigeaki Umeda, Roshan Sharma

Cancer Res· December 2025

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The Noncoding Mutational Landscape of Pancreatic Cancer Reveals Recurrent Somatic Mutations in Enhancer Regions.
Akimasa Hayashi, Yu-Jui Ho, Alvin P Makohon-Moore, Amanda Zucker, Jungeui Hong

Cancer Res Commun· October 2025

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Glioblastoma, IDH-wildtype manifesting as intracranial hemorrhage: A case report highlighting the clinical utility of digital polymerase chain reaction in integrated diagnoses.
Yukino Nikai, Kaishi Satomi, Kuniaki Saito, Miho Gomyo, Yuko Matsushita, Akimasa Hayashi

Neuropathology· August 2025

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mRNA vaccination mitigates pathological retinochoroidal neovascularization in animal models.
Yasuo Yanagi, Hinako Ichikawa, Le Bui Thao Nguyen, Akimasa Hayashi, Naoko Abe

Vaccine· August 2025

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Epigenetic evolution and clinicopathological implications of distinct DNA methylation profiles in pancreatic ductal adenocarcinoma.
Keiichiro Kitahama, Yu-Jui Ho, Kaishi Satomi, Takahiro Shibayama, Kiyotaka Nagahama, Akimasa Hayashi

Sci Rep· August 2025

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MYB::QKI fusion-positive diffuse glioma of the cerebellum: A case report.
Kaishi Satomi, Takahiro Shibayama, Takashi Hibiya, Akimasa Hayashi, Kiyotaka Nagahama

Neuropathology· June 2025

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Inflammation-Associated Carcinogenesis in Inflammatory Bowel Disease: Clinical Features and Molecular Mechanisms.
Tadakazu Hisamatsu, Jun Miyoshi, Noriaki Oguri, Hiromu Morikubo, Daisuke Saito, Akimasa Hayashi

Cells· April 2025

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The Evolutionary Forest of Pancreatic Cancer.
Katelyn M Mullen, Jungeui Hong, Marc A Attiyeh, Akimasa Hayashi, Hitomi Sakamoto

Cancer Discov· February 2025

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A Targetable Secreted Neural Protein Drives Pancreatic Cancer Metastatic Colonization and HIF1α Nuclear Retention.
Norihiro Yamaguchi, Y Gloria Wu, Ethan Ravetch, Mai Takahashi, Abdul G Khan, Akimasa Hayashi

Cancer Discov· December 2024

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Gastric mesenchymal tumor with gastroblastoma-like features harboring PTCH1::GLI2 fusion.
Takahiro Shibayama, Akimasa Hayashi, Nobutsugu Abe, Atsuko Ohki, Kaishi Satomi

Virchows Arch· September 2024

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Combination immunohistochemistry for CK5/6, p63, GATA6, and HNF4a predicts clinical outcome in treatment-naïve pancreatic ductal adenocarcinoma.
Takahiro Shibayama, Akimasa Hayashi, Masao Toki, Keiichiro Kitahama, Yu-Jui Ho

Sci Rep· July 2024

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Ovarian Sex Cord Tumor Harboring FUS::CREM Fusion : An Ovarian Counterpart of Inflammatory and Nested Testicular Sex Cord Tumor?
Takahiro Shibayama, Akimasa Hayashi, Kiyotaka Nagahama, Takashi Hibiya, Hiromi Shibuya

Am J Surg Pathol· June 2024

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Carrier-free mRNA vaccine induces robust immunity against SARS-CoV-2 in mice and non-human primates without systemic reactogenicity.
Saed Abbasi, Miki Matsui-Masai, Fumihiko Yasui, Akimasa Hayashi, Theofilus A Tockary

Mol Ther· May 2024

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Poly(ethylene Glycol) (PEG)-OligoRNA Hybridization to mRNA Enables Fine-Tuned Polyplex PEGylation for Spleen-Targeted mRNA Delivery.
Miki Suzuki, Yuki Mochida, Mao Hori, Akimasa Hayashi, Kazuko Toh

Small Sci· April 2024

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Immuno-genomic analysis reveals eosinophilic feature and favorable prognosis of female non-smoking esophageal squamous cell carcinomas.
Yuki Okawa, Shota Sasagawa, Hiroaki Kato, Todd A Johnson, Koji Nagaoka, Akimasa Hayashi

Cancer Lett· January 2024

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The role of nonlinear dimension reduction of genome-wide DNA methylome in integrated diagnosis: A case study of glioblastoma, IDH-wildtype.
Kaishi Satomi, Kuniaki Saito, Hiroaki Shimoyamada, Hiromi Onizuka, Takahiro Shibayama, Akimasa Hayashi

Pathol Int· October 2023

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A case of low-grade intestinal-type mucinous neoplasm of the fallopian tube with KRAS exon 2 mutation.
Kiyotaka Nagahama, Aya Isomura, Akimasa Hayashi, Mai Momomura, Yoichi Kobayashi

Gynecol Oncol Rep· October 2023

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Pulmonary inflammatory leiomyosarcoma represents a potential diagnostic pitfall of DNA methylation-based classification of sarcomas: a case report.
Takahiro Shibayama, Kaishi Satomi, Ryota Tanaka, Akihiko Yoshida, Kiyotaka Nagahama, Akimasa Hayashi

BMC Pulm Med· September 2023

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Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment.
Theofilus A Tockary, Saed Abbasi, Miki Matsui-Masai, Akimasa Hayashi, Naoto Yoshinaga

Proc Natl Acad Sci U S A· July 2023

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Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse.
Susan DeWolf, Yuval Elhanati, Katherine Nichols, Nicholas R Waters, Chi L Nguyen, Akimasa Hayashi

Sci Transl Med· July 2023

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Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer.
Haochen Zhang, Elias-Ramzey Karnoub, Shigeaki Umeda, Ronan Chaligné, Ignas Masilionis, Akimasa Hayashi

Nat Commun· February 2023

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Genomic analysis of circulating tumor cells in adenosquamous carcinoma of the prostate: a case report.
Junji Kitamura, Satoru Taguchi, Takatsugu Okegawa, Kazuki Honda, Toshihiko Kii, Akimasa Hayashi

BMC Med Genomics· September 2021

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Genetic and epigenetic basis of hepatoblastoma diversity.
Genta Nagae, Shogo Yamamoto, Masashi Fujita, Takanori Fujita, Aya Nonaka, Akimasa Hayashi

Nat Commun· September 2021

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TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma.
Kiyokazu Shirai, Genta Nagae, Motoaki Seki, Yotaro Kudo, Asuka Kamio, Akimasa Hayashi

Cancer Sci· July 2021

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The pancreatic cancer genome revisited.
Akimasa Hayashi, Jungeui Hong, Christine A Iacobuzio-Donahue

Nat Rev Gastroenterol Hepatol· July 2021

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