Publications by authors named "Akio Satow"

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Antipsychotic effects of N-desmethylclozapine on sensorimotor gating function in rats--possible involvement of activation of M(1) muscarinic receptors.
Shunsuke Maehara, Akio Satow, Hirohiko Hikichi, Hisashi Ohta

Eur J Pharmacol· September 2011

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Effects of a novel metabotropic glutamate receptor 7 negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazonolo[4,5-c]pyridin-4(5H)-one (MMPIP), on the central nervous system in rodents.
Hirohiko Hikichi, Takeshi Murai, Shoki Okuda, Shunsuke Maehara, Akio Satow

Eur J Pharmacol· August 2010

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Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice.
Hirohiko Hikichi, Miho Nishino, Miyuki Fukushima, Akio Satow, Shunsuke Maehara

Eur J Pharmacol· August 2010

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Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist.
Atsushi Satoh, Yasushi Nagatomi, Yukari Hirata, Satoru Ito, Gentaroh Suzuki, Akio Satow

Bioorg Med Chem Lett· September 2009

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Discovery and biological profile of isoindolinone derivatives as novel metabotropic glutamate receptor 1 antagonists: a potential treatment for psychotic disorders.
Satoru Ito, Yukari Hirata, Yasushi Nagatomi, Atsushi Satoh, Gentaroh Suzuki, Akio Satow

Bioorg Med Chem Lett· September 2009

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Quantification of mouse pulmonary cancer models by microcomputed tomography imaging.
Hiroshi Fushiki, Tomoko Kanoh-Azuma, Masahiro Katoh, Ken Kawabata, Jian Jiang, Akio Satow

Cancer Sci· August 2009

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Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one.
Akio Satow, Gentaroh Suzuki, Shunsuke Maehara, Hirohiko Hikichi, Takeshi Murai

J Pharmacol Exp Ther· July 2009

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Correlation of receptor occupancy of metabotropic glutamate receptor subtype 1 (mGluR1) in mouse brain with in vivo activity of allosteric mGluR1 antagonists.
Gentaroh Suzuki, Hiroko Kawagoe-Takaki, Takao Inoue, Toshifumi Kimura, Hirohiko Hikichi, Akio Satow

J Pharmacol Sci· July 2009

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Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia.
Shunsuke Maehara, Hirohiko Hikichi, Akio Satow, Shoki Okuda, Hisashi Ohta

Pharmacol Biochem Behav· November 2008

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Discovery and biological profile of 4-(1-aryltriazol-4-yl)-tetrahydropyridines as an orally active new class of metabotropic glutamate receptor 1 antagonist.
Satoru Ito, Atsushi Satoh, Yasushi Nagatomi, Yukari Hirata, Gentaroh Suzuki, Akio Satow

Bioorg Med Chem· November 2008

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Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide].
Akio Satow, Shunsuke Maehara, Satoko Ise, Hirohiko Hikichi, Miyuki Fukushima

J Pharmacol Exp Ther· August 2008

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Face-washing behavior induced by the group I metabotropic glutamate receptor agonist (S)-3,5-DHPG in mice is mediated by mGlu1 receptor.
Hirohiko Hikichi, Yuki Iwahori, Takeshi Murai, Shunsuke Maehara, Akio Satow

Eur J Pharmacol· May 2008

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Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC).
Gentaroh Suzuki, Toshifumi Kimura, Akio Satow, Naoki Kaneko, Junko Fukuda

J Pharmacol Exp Ther· June 2007

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