Publications by authors named "Alaattin Sen"

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A series of 4-thiomorpholinophenyl-thiosemicarbazones as cholinesterase inhibitors with anti-neuroblastoma effects.
Hina Aftab, Furkan Çakır, Gurbet Çelik Turgut, Nastaran Sadeghian, Rima D Alharthy

Bioorg Chem· December 2025

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Neuroinflammatory Human Brain Organoids Enable Comprehensive Drug Screening Studies: Fingolimod and its Analogues in Focus.
Busra Acar, Nihan Aktas Pepe, Aleksandra Zivkovic, Holger Stark, Alaattin Sen

Curr Med Chem· October 2025

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Therapeutic Potential of Nitrogen-Substituted Oleanolic Acid Derivatives in Neuroinflammatory and Cytokine Pathways: Insights From Cell-Based and Computational Models.
Gurbet Çelik Turgut, Nihan Aktaş Pepe, Yağmur Ceylan Ekiz, Halil Şenol, Alaattin Şen

Chem Biodivers· September 2025

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Novel thiazolidinedione hybrids as cholinesterase inhibitors and targeting neuroblastoma: design, synthesis, in vitro and in silico biological evaluations.
Gurbet Çelik Turgut, Furkan Çakır, Alaattin Şen, Feyzi Sinan Tokalı, Halil Şenol

Bioorg Chem· September 2025

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Synthesis, Characterization, and Comprehensive In Vitro and In Silico Evaluation of the Anti-Inflammatory Potential of Novel 1,2,3-Triazole-Arylidenehydrazide/Thiazolidinone Hybrids.
Nihan Aktaş Pepe, Furkan Çakır, Tuğba Atalay, Büşra Acar, Gurbet Çelik Turgut

Arch Pharm (Weinheim)· September 2025

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Cinnamomum zeylanicum extract incorporated electrospun poly(lactic acid)/gelatin membrane as a new wound dressing.
Seray Zora Tarhan, Nihan Aktaş Pepe, Alaattin Şen, İsmail Alper İşoğlu

Int J Biol Macromol· August 2025

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Possible Drug-Drug Interactions Between Mesalamine and Tricyclic Antidepressants Through CYP2D6 Metabolism - In silico and In vitro Analyses.
Melek B Ozen, Isil Gazioglu, Ozden Ozgun Acar, Huseyin Guner, Gurkan Semiz, Alaattin Sen

Drug Res (Stuttg)· June 2025

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Role of Long Non-Coding RNA X-Inactive-Specific Transcript () in Neuroinflammation and Myelination: Insights from Cerebral Organoids and Implications for Multiple Sclerosis.
Nihan Aktas Pepe, Busra Acar, Gozde Erturk Zararsiz, Serife Ayaz Guner, Alaattin Sen

Noncoding RNA· April 2025

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Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer's Disease.
Tugba Uçar Akyürek, Ilkay Erdogan Orhan, F Sezer Şenol Deniz, Gokcen Eren, Busra Acar, Alaattin Sen

Pharmaceuticals (Basel)· October 2024

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Role of AHR, NF-kB and CYP1A1 crosstalk with the X protein of Hepatitis B virus in hepatocellular carcinoma cells.
Gurbet Celik-Turgut, Nazmiye Olmez, Tugba Koc, Ozden Ozgun-Acar, Asli Semiz, Alaattin Sen

Gene· February 2023

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Synthesis and Comprehensive in Vivo Activity Profiling of Olean-12-en-28-ol, 3β-Pentacosanoate in Experimental Autoimmune Encephalomyelitis: A Natural Remyelinating and Anti-Inflammatory Agent.
Halil Senol, Ozden Ozgun-Acar, Aydan Dağ, Ahmet Eken, Hüseyin Guner, Alaattin Sen

J Nat Prod· January 2023

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Evaluation of Anti-Alzheimer Activity of Synthetic Coumarins by Combination of in Vitro and in Silico Approaches.
Ilkay Erdogan Orhan, F Sezer Senol Deniz, Ramin Ekhteiari Salmas, Sule Irmak, Ozden Ozgun Acar, Alaattin Sen

Chem Biodivers· December 2022

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Biochemical, pharmacological, and toxicological attributes of caper () flowering buds and berries pickles.
Ozden Ozgun-Acar, Gurbet Celik-Turgut, Hüseyin Guner, Serdar Sezer, Alaattin Sen

Food Sci Nutr· December 2022

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Complementary medicines used in ulcerative colitis and unintended interactions with cytochrome P450-dependent drug-metabolizing enzymes.
Alaattin Şen

Turk J Med Sci· October 2022

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Cerium Oxide Nanoparticles Biosynthesized Using Fresh Green Walnut Shell in Microwave Environment and their Anticancer Effect on Breast Cancer Cells.
Mine Sulak, Gurbet Celik Turgut, Alaattin Sen

Chem Biodivers· August 2022

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Triterpenoids and steroids isolated from Anatolian and their activity on the expression of inflammatory cytokines.
Isil Gazioglu, Sevcan Semen, Ozden Ozgun Acar, Ufuk Kolak, Alaattin Sen

Pharm Biol· December 2020

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Suppression of Inflammatory Cytokines Expression with Bitter Melon () in TNBS-instigated Ulcerative Colitis.
Asli Semiz, Ozden Ozgun Acar, Hulya Cetin, Gurkan Semiz, Alaattin Sen

J Transl Int Med· September 2020

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Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases.
Alaattin Sen

World J Clin Cases· May 2020

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Role of cytochrome P450 polymorphisms and functions in development of ulcerative colitis.
Alaattin Sen, Holger Stark

World J Gastroenterol· June 2019

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Synthesis and Functional Investigations of Computer Designed Novel Cladribine-Like Compounds for the Treatment of Multiple Sclerosis.
Serkan Yavuz, Aysu Çetin, Atilla Akdemir, Doğukan Doyduk, Ali Dişli

Arch Pharm (Weinheim)· November 2017

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Computer design, synthesis, and bioactivity analyses of drugs like fingolimod used in the treatment of multiple sclerosis.
Gurbet Çelik Turgut, Doğukan Doyduk, Yılmaz Yıldırır, Serkan Yavuz, Atilla Akdemir

Bioorg Med Chem· January 2017

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Modulatory role of GSTM1 null genotype on the frequency of micronuclei in pesticide-exposed agricultural workers.
Tugba Boyunegmez Tumer, Seda Savranoglu, Pelin Atmaca, Gulsum Terzioglu, Alaattin Sen

Toxicol Ind Health· December 2016

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Contribution of ellagic acid on the antioxidant potential of medicinal plant Epilobium hirsutum.
Serdar Karakurt, Asli Semiz, Gurbet Celik, Ayse Mine Gencler-Ozkan, Alaattin Sen

Nutr Cancer· December 2016

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Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice.
Ozden Ozgun-Acar, Gurbet Celik-Turgut, Isil Gazioglu, Ufuk Kolak, Seda Ozbal, Alaattin Sen

J Neuroimmunol· September 2016

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Modulatory actions of o-coumaric acid on carcinogen-activating cytochrome P450 isozymes and the potential for drug interactions in human hepatocarcinoma cells.
Alaattin Sen, Gulsum Terzioglu, Pelin Atmaca, Gurbet Celik, Ozden Ozgun

Pharm Biol· April 2016

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