Publications by authors named "Alam Maroof"

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Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis.
Anoop Arunagiri, Leena Haataja, Maroof Alam, Noah F Gleason, Emma Mastroianni

J Clin Invest· November 2025

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Editorial: Dietary and nutrigenetic contributors to metabolic syndrome.
Anoop Arunagiri, Maroof Alam, Erez Dror, Melkam A Kebede

Front Endocrinol (Lausanne)· June 2025

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Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation.
Bhaskar K Chatterjee, Maroof Alam, Arghya Chakravorty, Shannon M Lacy, William Giblin

ACS Chem Biol· April 2025

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Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation.
Bhaskar K Chatterjee, Maroof Alam, Arghya Chakravorty, Shannon M Lacy, Jason Rech

bioRxiv· July 2024

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Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Anoop Arunagiri, Maroof Alam, Leena Haataja, Hassan Draz, Bashiyer Alasad

Protein Sci· April 2024

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Nutrient-dependent regulation of β-cell proinsulin content.
Xiaoxi Xu, Anoop Arunagiri, Maroof Alam, Leena Haataja, Charles R Evans

J Biol Chem· July 2023

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Protective Effects of Rifampicin and Its Analog Rifampicin Quinone in a Mouse Model of Obesity-Induced Type 2 Diabetes.
Amit Garg, Maroof Alam, Shakuntala Bai, Monica Dandawate, Neeta Kumari

ACS Pharmacol Transl Sci· February 2023

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Proteasomal degradation of WT proinsulin in pancreatic beta cells.
Xiaoxi Xu, Anoop Arunagiri, Leena Haataja, Maroof Alam, Shuhui Ji

J Biol Chem· October 2022

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Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580-2594.
Maroof Alam, Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin

Diabetes· April 2022

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Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.
Maroof Alam, Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin

Diabetes· November 2021

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Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer.
Masayuki Hiraki, Takahiro Maeda, Neha Mehrotra, Caining Jin, Maroof Alam

Signal Transduct Target Ther· February 2021

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Normal and defective pathways in biogenesis and maintenance of the insulin storage pool.
Ming Liu, Yumeng Huang, Xiaoxi Xu, Xin Li, Maroof Alam

J Clin Invest· January 2021

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MUC1-C Induces PD-L1 and Immune Evasion in Triple-Negative Breast Cancer.
Takahiro Maeda, Masayuki Hiraki, Caining Jin, Hasan Rajabi, Ashujit Tagde, Maroof Alam

Cancer Res· January 2018

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Targeting MUC1-C suppresses polycomb repressive complex 1 in multiple myeloma.
Ashujit Tagde, Tahireh Markert, Hasan Rajabi, Masayuki Hiraki, Maroof Alam

Oncotarget· September 2017

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MUC1-C activates EZH2 expression and function in human cancer cells.
Hasan Rajabi, Masayuki Hiraki, Ashujit Tagde, Maroof Alam, Audrey Bouillez

Sci Rep· August 2017

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MUC1-C promotes the suppressive immune microenvironment in non-small cell lung cancer.
Audrey Bouillez, Dennis Adeegbe, Caining Jin, Xiufeng Hu, Ashujit Tagde, Maroof Alam

Oncoimmunology· July 2017

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Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.
Rehan Ahmad, Maroof Alam, Masanori Hasegawa, Yasumitsu Uchida, Omar Al-Obaid

Mol Cancer· February 2017

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MUC1-C Represses the Crumbs Complex Polarity Factor CRB3 and Downregulates the Hippo Pathway.
Maroof Alam, Audrey Bouillez, Ashujit Tagde, Rehan Ahmad, Hasan Rajabi

Mol Cancer Res· December 2016

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MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia.
Ashujit Tagde, Hasan Rajabi, Dina Stroopinsky, Reddy Gali, Maroof Alam

Oncotarget· June 2016

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MUC1-C drives MYC in multiple myeloma.
Ashujit Tagde, Hasan Rajabi, Audrey Bouillez, Maroof Alam, Reddy Gali

Blood· May 2016

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MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors.
Masayuki Hiraki, Yozo Suzuki, Maroof Alam, Kunihiko Hinohara, Masanori Hasegawa

Sci Rep· May 2016

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Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas.
Audrey Bouillez, Hasan Rajabi, Sean Pitroda, Caining Jin, Maroof Alam

Cancer Res· March 2016

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Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.
Masanori Hasegawa, Hidekazu Takahashi, Hasan Rajabi, Maroof Alam, Yozo Suzuki

Oncotarget· March 2016

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Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma.
Salvia Jain, Dina Stroopinsky, Li Yin, Jacalyn Rosenblatt, Maroof Alam

Blood· July 2015

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Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle Formulation.
Masanori Hasegawa, Raj Kumar Sinha, Manoj Kumar, Maroof Alam, Li Yin

Clin Cancer Res· May 2015

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