Publications by authors named "Dennis Adeegbe"

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Single-cell analysis of localized prostate cancer patients links high Gleason score with an immunosuppressive profile.
Victor R Adorno Febles, Yuan Hao, Aarif Ahsan, Jiansheng Wu, Yingzhi Qian, Dennis O Adeegbe

Prostate· June 2023

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Editorial: Regulatory T lymphocytes in cancer immunity.
Dennis Adeegbe, Joseph Barbi, James Wing

Front Immunol· November 2022

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The Yin and Yang of Targeting KLRG1 Tregs and Effector Cells.
Samantha M Borys, Arup K Bag, Laurent Brossay, Dennis O Adeegbe

Front Immunol· May 2022

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Tumor-associated Tregs obstruct antitumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells.
David Noyes, Arup Bag, Saheed Oseni, Jon Semidey-Hurtado, Ling Cen, Dennis Adeegbe

J Immunother Cancer· May 2022

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Coupling the immunomodulatory properties of the HDAC6 inhibitor ACY241 with Oxaliplatin promotes robust anti-tumor response in non-small cell lung cancer.
Arup Bag, Andrew Schultz, Saloni Bhimani, Olya Stringfield, William Dominguez, Dennis Adeegbe

Oncoimmunology· April 2022

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Circulating Immunosuppressive Regulatory T Cells Predict Risk of Incident Cutaneous Squamous Cell Carcinoma.
Dana E Rollison, Jane L Messina, Basil S Cherpelis, Neil A Fenske, Michael J Schell, Dennis O Adeegbe

Front Med (Lausanne)· November 2021

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Targeted Therapy Given after Anti-PD-1 Leads to Prolonged Responses in Mouse Melanoma Models through Sustained Antitumor Immunity.
Manali S Phadke, Zhihua Chen, Jiannong Li, Eslam Mohamed, Michael A Davies, Dennis O Adeegbe

Cancer Immunol Res· May 2021

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Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy.
Qianxing Mo, Roger Li, Dennis O Adeegbe, Guang Peng, Keith Syson Chan

Commun Biol· December 2020

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Wei Wang, Jill M Marinis, Allison M Beal, Shivraj Savadkar, Yue Wu, Dennis Adeegbe

Cancer Cell· October 2020

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Innate αβ T Cells Mediate Antitumor Immunity by Orchestrating Immunogenic Macrophage Programming.
Mautin Hundeyin, Emma Kurz, Ankita Mishra, Juan Andres Kochen Rossi, Shannon M Liudahl, Dennis O Adeegbe

Cancer Discov· September 2019

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Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Danbee Ha, Atsushi Tanaka, Tatsuya Kibayashi, Atsushi Tanemura, Daisuke Sugiyama, Dennis Adeegbe

Proc Natl Acad Sci U S A· January 2019

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Intron retention is a source of neoepitopes in cancer.
Alicia C Smart, Claire A Margolis, Harold Pimentel, Meng Xiao He, Diana Miao, Dennis Adeegbe

Nat Biotechnol· December 2018

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Wei Wang, Jill M Marinis, Allison M Beal, Shivraj Savadkar, Yue Wu, Dennis Adeegbe

Cancer Cell· November 2018

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Assessing Therapeutic Efficacy of MEK Inhibition in a KRAS-Driven Mouse Model of Lung Cancer.
Shuai Li, Shengwu Liu, Jiehui Deng, Esra A Akbay, Josephine Hai, Dennis O Adeegbe

Clin Cancer Res· October 2018

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BET Bromodomain Inhibition Cooperates with PD-1 Blockade to Facilitate Antitumor Response in -Mutant Non-Small Cell Lung Cancer.
Dennis O Adeegbe, Shengwu Liu, Maureen M Hattersley, Michaela Bowden, Chensheng W Zhou

Cancer Immunol Res· October 2018

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Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors.
Diana Miao, Claire A Margolis, Natalie I Vokes, David Liu, Amaro Taylor-Weiner, Dennis Adeegbe

Nat Genet· September 2018

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NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model.
Yan Liu, Yuyang Li, Shengwu Liu, Dennis O Adeegbe, Camilla L Christensen

Cancer Res· July 2018

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Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.
Dennis O Adeegbe, Yan Liu, Patrick H Lizotte, Yusuke Kamihara, Amir R Aref

Cancer Discov· August 2017

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MUC1-C promotes the suppressive immune microenvironment in non-small cell lung cancer.
Audrey Bouillez, Dennis Adeegbe, Caining Jin, Xiufeng Hu, Ashujit Tagde

Oncoimmunology· July 2017

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The Lower Limit of Regulatory CD4 Foxp3 TCRβ Repertoire Diversity Required To Control Autoimmunity.
Aixin Yu, Michael J Dee, Dennis Adeegbe, Connor J Dwyer, Norman H Altman

J Immunol· April 2017

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Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.
Suzanne George, Diana Miao, George D Demetri, Dennis Adeegbe, Scott J Rodig

Immunity· February 2017

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Regulatory T cells in cancer; can they be controlled?
Dennis O Adeegbe, Hiroyoshi Nishikawa

Immunotherapy· June 2016

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Detection of self-reactive CD8⁺ T cells with an anergic phenotype in healthy individuals.
Yuka Maeda, Hiroyoshi Nishikawa, Daisuke Sugiyama, Danbee Ha, Masahide Hamaguchi, Dennis Adeegbe

Science· December 2014

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Natural and induced T regulatory cells in cancer.
Dennis O Adeegbe, Hiroyoshi Nishikawa

Front Immunol· July 2013

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Allogeneic T regulatory cell-mediated transplantation tolerance in adoptive therapy depends on dominant peripheral suppression and central tolerance.
Dennis Adeegbe, Robert B Levy, Thomas R Malek

Blood· March 2010

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