Publications by authors named "Alan Chu"

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Drug repurposing screen identifies an HRI activating compound that promotes adaptive mitochondrial remodeling in MFN2-deficient cells.
Prerona Bora, Mashiat Zaman, Samantha Oviedo, Sergei Kutseikin, Nicole Madrazo, Alan Chu

Proc Natl Acad Sci U S A· December 2025

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Pharmacological targeting of RIG-I can selectively activate the integrated stress response.
Caroline A Cuoco, Wen Ren, Kelsey R Baron, Sakina Gologo, Valerie Perea, Alan Chu

Sci Adv· October 2025

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Drug Repurposing Screen Identifies an HRI Activating Compound that Promotes Adaptive Mitochondrial Remodeling in MFN2-deficient Cells.
Prerona Bora, Mashiat Zaman, Samantha Oviedo, Sergei Kutseikin, Nicole Madrazo, Alan Chu

bioRxiv· June 2025

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RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma.
Alan Chu, Xiao Liu, Shijia Liu, Mengxi Li, Rui Song

Front Genet· April 2025

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Synthesis and Structure-Activity Relationship of Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease with Antiviral Potency.
Catherine C Rouch, Arnab K Chatterjee, Connor McCarty, Lirui Song, Alan Chu

Bioorg Med Chem Lett· February 2025

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GPD1L may inhibit the development of esophageal squamous cell carcinoma through the PI3K/AKT signaling pathway: bioinformatics analysis and experimental exploration.
LanLan Gan, Lu Zhou, ALan Chu, Chen Sun, YongTai Wang

Mol Biol Rep· November 2024

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Bioinformatics analysis and experimental verification of NLRX1 as a prognostic factor for esophageal squamous cell carcinoma.
Lu Zhou, Lanlan Gan, Chen Sun, Alan Chu, Menglin Yang

Oncol Lett· June 2024

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Circ-POSTN promotes the progression and reduces radiosensitivity in esophageal cancer by regulating the miR-876-5p/FYN axis.
Alan Chu, Chen Sun, Zongwen Liu, Shijia Liu, Mengxi Li

Thorac Cancer· May 2024

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Targeted therapy or immunotherapy in BRAF-mutated metastatic melanoma: a Spanish center's decade of experience.
Chen Sun, Sofia España, Nina Richarz, Carme Solé-Blanch, Aram Boada, Alan Chu

Front Oncol· February 2024

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Hsa_circ_0052611 and mir-767-5p guide the warburg effect, migration, and invasion of BRCA cells through modulating SCAI.
Xin Wang, Zongwen Liu, Alan Chu, Rui Song, Shijia Liu

J Bioenerg Biomembr· October 2023

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PARP inhibitors combined with radiotherapy: are we ready?
Chen Sun, Alan Chu, Rui Song, Shijia Liu, Ting Chai

Front Pharmacol· October 2023

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Knockdown of circMFN2 inhibits cell progression and glycolysis by miR-198/CUL4B pathway in ovarian cancer.
Rui Song, Ting Chai, Junqi Liu, Alan Chu, Chen Sun

J Biochem Mol Toxicol· August 2023

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Targeting FoxO transcription factors with HDAC inhibitors for the treatment of osteoarthritis.
Hiroki Ohzono, Yiwen Hu, Keita Nagira, Haruhisa Kanaya, Naoki Okubo, Alan C Chu

Ann Rheum Dis· February 2023

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Unusual Presentation of Gallbladder Fossa Abscess Following Open Cholecystectomy in a Patient With Cholecystitis: A Case Report.
Hirva Vyas, Ethan Burg, Ramtin Moradi, Alan Chu, Davood K Hosseini

Cureus· May 2022

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Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.
Nicholas L Yan, Reji Nair, Alan Chu, Ian A Wilson, Kristen A Johnson

Bioorg Med Chem Lett· March 2022

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Effects of Intensive Outpatient Integrative Medicine on Health Care Utilization on High Utilizer Patients at a Major Academic Health System.
Annie Zhang, Alan Chu, Sun Yoo, Andrew Shubov

J Altern Complement Med· September 2021

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Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.
Nicholas L Yan, Diogo Santos-Martins, Reji Nair, Alan Chu, Ian A Wilson

J Med Chem· May 2021

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Cardiac Tamponade.
Alan Chu, Jennifer Yee

J Educ Teach Emerg Med· October 2020

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Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic.
Emily N Chin, Chenguang Yu, Vincent F Vartabedian, Ying Jia, Manoj Kumar, Alan Chu, Peter G Schultz

Science· August 2020

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Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.
Donatella Chianelli, Paul V Rucker, Jason Roland, David C Tully, John Nelson, Alan Chu

J Med Chem· April 2020

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Experimental Study and Clinical Observation on the Improvement Effect of Lienal Polypeptide on Blood Toxicity and Immune Injury Induced by Radiotherapy.
Alan Chu, Rui Song, Ge Hou, Jinjin Yuan, Cheng Wang

Genet Test Mol Biomarkers· February 2020

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Inadvertent quadriceps weakness following the pericapsular nerve group (PENG) block.
Hai Chuan Yu, Joanna J Moser, Alan Y Chu, Shaylyn H Montgomery, Nathan Brown

Reg Anesth Pain Med· May 2019

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A Comprehensive Quantitative Genetic Analysis of Cerebral Surface Area in Youth.
J Eric Schmitt, Michael C Neale, Liv S Clasen, Siyuan Liu, Jakob Seidlitz, Alan Chu

J Neurosci· April 2019

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Identification of abnormal nuclear and mitochondrial genes in esophageal cancer cells.
Zongwen Liu, Ting Chai, Yan Zhang, Alan Chu, Bing Liang

Mol Med Rep· February 2018

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High incidence of coding gene mutations in mitochondrial DNA in esophageal cancer.
Zong-Wen Liu, Zhen-Jiang Guo, A-Lan Chu, Yan Zhang, Bing Liang

Mol Med Rep· December 2017

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