Publications by authors named "Alan Costello"

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Co-circulating pathogens of humans: a systematic review of mechanistic transmission models.
Kelsey E Shaw, Jennifer K Peterson, Neda Jalali, Saikanth Ratnavale, Manar Alkuzweny, Alan Costello

Proc Biol Sci· September 2025

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Efficient genetic code expansion without host genome modifications.
Alan Costello, Alexander A Peterson, David L Lanster, Zhiyi Li, Gavriela D Carver

Nat Biotechnol· July 2025

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Author Correction: Efficient genetic code expansion without host genome modifications.
Alan Costello, Alexander A Peterson, David L Lanster, Zhiyi Li, Gavriela D Carver

Nat Biotechnol· July 2025

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Genetic Code Expansion History and Modern Innovations.
Alan Costello, Alexander A Peterson, Pei-Hsin Chen, Rustam Bagirzadeh, David L Lanster

Chem Rev· November 2024

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Conditional Knockdown of Endogenous MicroRNAs in CHO Cells Using TET-ON-SanDI Sponge Vectors.
Alan Costello, Nga Lao, Martin Clynes, Niall Barron

Methods Mol Biol· October 2024

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miRNA- and Cell Line-Specific Constraints on Precursor miRNA Processing of Stably Transfected Pancreatic Cancer and Other Mammalian Cells.
Taylor J Allen-Coyle, Berta Capella Roca, Alan Costello, Niall Barron, Joanne Keenan

Int J Mol Sci· May 2024

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Impacts of K-12 school reopening on the COVID-19 epidemic in Indiana, USA.
Guido España, Sean Cavany, Rachel Oidtman, Carly Barbera, Alan Costello

Epidemics· December 2021

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Directed evolution of rRNA improves translation kinetics and recombinant protein yield.
Fan Liu, Siniša Bratulić, Alan Costello, Teemu P Miettinen, Ahmed H Badran

Nat Commun· September 2021

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Synthetic Biological Circuits within an Orthogonal Central Dogma.
Alan Costello, Ahmed H Badran

Trends Biotechnol· January 2021

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Development of whole-cell and cell-free biosensors for the detection and differentiation of organic and inorganic forms of copper.
Alan Costello, Joanne Parker, Martin Clynes, Richard Murphy

Metallomics· November 2020

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Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells.
Ioanna Tzani, Craig Monger, Krishna Motheramgari, Clair Gallagher, Ryan Hagan, Alan Costello

Biotechnol Bioeng· August 2020

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Reinventing the Wheel: Synthetic Circular RNAs for Mammalian Cell Engineering.
Alan Costello, Nga T Lao, Niall Barron, Martin Clynes

Trends Biotechnol· February 2020

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Leaky Expression of the TET-On System Hinders Control of Endogenous miRNA Abundance.
Alan Costello, Nga T Lao, Clair Gallagher, Berta Capella Roca, Lourdes A N Julius

Biotechnol J· March 2019

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Continuous translation of circularized mRNA improves recombinant protein titer.
Alan Costello, Nga T Lao, Niall Barron, Martin Clynes

Metab Eng· March 2019

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Improved yield of rhEPO in CHO cells with synthetic 5' UTR.
Alan Costello, Nga T Lao, Niall Barron, Martin Clynes

Biotechnol Lett· February 2019

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Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal hydrolase 14.
Alan Costello, Orla Coleman, Nga T Lao, Michael Henry, Paula Meleady

J Biotechnol· December 2018

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A proteomic profiling dataset of recombinant Chinese hamster ovary cells showing enhanced cellular growth following miR-378 depletion.
Orla Coleman, Alan Costello, Michael Henry, Nga T Lao, Niall Barron

Data Brief· December 2018

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Conditional Knockdown of Endogenous MicroRNAs in CHO Cells Using TET-ON-SanDI Sponge Vectors.
Alan Costello, Nga Lao, Martin Clynes, Niall Barron

Methods Mol Biol· February 2018

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Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells.
Paul S Kelly, Colin Clarke, Alan Costello, Craig Monger, Justine Meiller

Metab Eng· May 2017

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