Publications by authors named "Alan D Frankel"

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The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition.
Amber M Smith, Yang Li, Arianna Velarde, Yifan Cheng, Alan D Frankel

Mol Cell· August 2025

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Correction: Functional and structural segregation of overlapping helices in HIV-1.
Maliheh Safari, Bhargavi Jayaraman, Henni Zommer, Shumin Yang, Cynthia Smith, Alan D Frankel

Elife· January 2025

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The HIV-1 Nuclear Export Complex Reveals the Role of RNA in Crm1 Cargo Recognition.
Amber M Smith, Yang Li, Arianna Velarde, Yifan Cheng, Alan D Frankel

bioRxiv· September 2024

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Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk.
Yang Li, Xi Liu, Koh Fujinaga, John D Gross, Alan D Frankel

Sci Adv· January 2024

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Functional and structural segregation of overlapping helices in HIV-1.
Maliheh Safari, Bhargavi Jayaraman, Henni Zommer, Shumin Yang, Cynthia Smith, Alan D Frankel

Elife· May 2022

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Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling.
Jeffrey R Johnson, David C Crosby, Judd F Hultquist, Andrew P Kurland, Prithy Adhikary, Alan D Frankel

Cell Rep· April 2022

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Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions.
Christopher R Carlson, Jonathan B Asfaha, Chloe M Ghent, Conor J Howard, Nairi Hartooni, Alan D Frankel

Mol Cell· December 2020

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A Quantitative Genetic Interaction Map of HIV Infection.
David E Gordon, Ariane Watson, Assen Roguev, Simin Zheng, Gwendolyn M Jang, Alan D Frankel

Mol Cell· April 2020

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ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.
Ruth Hüttenhain, Jiewei Xu, Lily A Burton, David E Gordon, Judd F Hultquist, Alan D Frankel

Cell Host Microbe· July 2019

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Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability.
Bhargavi Jayaraman, Jason D Fernandes, Shumin Yang, Cynthia Smith, Alan D Frankel

Sci Rep· March 2019

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Discovery of a Branched Peptide That Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication.
Yumin Dai, Jessica E Wynn, Ashley N Peralta, Chringma Sherpa, Bhargavi Jayaraman, Alan D Frankel

J Med Chem· November 2018

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The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Alan D Frankel

Elife· May 2018

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Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription.
Tyler B Faust, Jennifer M Binning, John D Gross, Alan D Frankel

Annu Rev Virol· September 2017

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Identification and Optimization of Thienopyridine Carboxamides as Inhibitors of HIV Regulatory Complexes.
Robert L Nakamura, Mark A Burlingame, Shumin Yang, David C Crosby, Dale J Talbot, Alan D Frankel

Antimicrob Agents Chemother· July 2017

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PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription.
Tyler B Faust, Yang Li, Gwendolyn M Jang, Jeffrey R Johnson, Shumin Yang, Alan D Frankel

Sci Rep· March 2017

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Functional Segregation of Overlapping Genes in HIV.
Jason D Fernandes, Tyler B Faust, Nicolas B Strauli, Cynthia Smith, David C Crosby, Alan D Frankel

Cell· December 2016

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Oligomeric viral proteins: small in size, large in presence.
Bhargavi Jayaraman, Amber M Smith, Jason D Fernandes, Alan D Frankel

Crit Rev Biochem Mol Biol· September 2016

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A structurally plastic ribonucleoprotein complex mediates post-transcriptional gene regulation in HIV-1.
Jason D Fernandes, David S Booth, Alan D Frankel

Wiley Interdiscip Rev RNA· July 2016

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Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins.
Bryan M Dunyak, Robert L Nakamura, Alan D Frankel, Jason E Gestwicki

ACS Chem Biol· November 2015

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Thermodynamics of Rev-RNA interactions in HIV-1 Rev-RRE assembly.
Bhargavi Jayaraman, David Mavor, John D Gross, Alan D Frankel

Biochemistry· October 2015

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RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex.
Bhargavi Jayaraman, David C Crosby, Christina Homer, Isabel Ribeiro, David Mavor, Alan D Frankel

Elife· December 2014

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The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA.
David S Booth, Yifan Cheng, Alan D Frankel

Elife· December 2014

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A cell-based method for screening RNA-protein interactions: identification of constitutive transport element-interacting proteins.
Robert L Nakamura, Stephen G Landt, Emily Mai, Jemiel Nejim, Lily Chen, Alan D Frankel

PLoS One· May 2013

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Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.
Iván D'Orso, Gwendolyn M Jang, Alexander W Pastuszak, Tyler B Faust, Elizabeth Quezada, Alan D Frankel

Mol Cell Biol· December 2012

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