Publications by authors named "Alan DiSpirito"

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Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by Cu PET/MRI.
Emilie Munk Lynderup, Mikkel Holm Vendelbo, Frederik Teicher Kirk, Karina Højrup Vase, Aage Kristian Olsen Alstrup, Alan A DiSpirito

Br J Pharmacol· January 2026

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Rapid transcellular hepatic copper depletion by ARBM-101 rescues severe liver damage in Wilson disease rodents.
Jonas Engler, Eun-Jung Kim, Dasol Kim, Noreene M Shibata, Emilie Munk Lynderup, Alan A DiSpirito

Biomed Pharmacother· December 2025

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Copper impairs the intestinal barrier integrity in Wilson disease.
Adriana Fontes, Hannah Pierson, Joanna B Bierła, Carola Eberhagen, Jennifer Kinschel, Ana M DiSpirito, Alan DiSpirito

Metabolism· September 2024

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Heterologous Biosynthesis of Methanobactin from sp. Strain SB2 in OB3b.
Peng Peng, Alan A DiSpirito, Braden J Lewis, Joel D Nott, Jeremy D Semrau

ACS Synth Biol· August 2024

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MmoD regulates soluble methane monooxygenase and methanobactin production in OB3b.
Peng Peng, Junwon Yang, Alan A DiSpirito, Jeremy D Semrau

Appl Environ Microbiol· December 2023

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Inhibition of nitrous oxide reduction in forest soil microcosms by different forms of methanobactin.
Jin Chang, Peng Peng, Muhammad Farhan Ul-Haque, Abid Hira, Alan A DiSpirito

Environ Microbiol· November 2023

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ARBM101 (Methanobactin SB2) Drains Excess Liver Copper via Biliary Excretion in Wilson's Disease Rats.
Claudia Einer, Ditte Emilie Munk, Eok Park, Banu Akdogan, Judith Nagel, Ana M DiSpirito, Alan A DiSpirito

Gastroenterology· July 2023

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Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2.
Andrew Stewart, Philip Dershwitz, Charles Stewart, Michael R Sawaya, Todd O Yeates, Alan A DiSpirito

Acta Crystallogr F Struct Biol Commun· May 2023

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Multiple Mechanisms for Copper Uptake by Methylosinus trichosporium OB3b in the Presence of Heterologous Methanobactin.
Peng Peng, Wenyu Gu, Alan A DiSpirito, Jeremy D Semrau

mBio· October 2022

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Diffusion of H S from anaerobic thiolated ligand biodegradation rapidly generates bioavailable mercury.
Benjamin R Stenzler, Rui Zhang, Jeremy D Semrau, Alan A DiSpirito, Alexandre J Poulain

Environ Microbiol· July 2022

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Variable Inhibition of Nitrous Oxide Reduction in Denitrifying Bacteria by Different Forms of Methanobactin.
Jin Chang, Peng Peng, Alan A DiSpirito, Jeremy D Semrau

Appl Environ Microbiol· April 2022

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Evidence for methanobactin "Theft" and novel chalkophore production in methanotrophs: impact on methanotrophic-mediated methylmercury degradation.
Christina S Kang-Yun, Xujun Liang, Philip Dershwitz, Wenyu Gu, Aloys Schepers, Alan A DiSpirito

ISME J· January 2022

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Two TonB-Dependent Transporters in Methylosinus trichosporium OB3b Are Responsible for Uptake of Different Forms of Methanobactin and Are Involved in the Canonical "Copper Switch".
Peng Peng, Christina S Kang-Yun, Jin Chang, Wenyu Gu, Alan A DiSpirito

Appl Environ Microbiol· January 2022

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MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b.
Philip Dershwitz, Wenyu Gu, Julien Roche, Christina S Kang-Yun, Jeremy D Semrau, Alan A DiSpirito

Appl Environ Microbiol· January 2022

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Spectroscopic and computational investigations of organometallic complexation of group 12 transition metals by methanobactins from Methylocystis sp. SB2.
Peter Eckert, Alexander Johs, Jeremy D Semrau, Alan A DiSpirito, Jocelyn Richardson

J Inorg Biochem· October 2021

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Oxygen Generation via Water Splitting by a Novel Biogenic Metal Ion-Binding Compound.
Philip Dershwitz, Nathan L Bandow, Junwon Yang, Jeremy D Semrau, Marcus T McEllistrem, Ana M DiSpirito, Alan A DiSpirito

Appl Environ Microbiol· June 2021

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Methanotrophy - Environmental, Industrial and Medical Applications.
Jeremy D Semrau, Alan A DiSpirito

Curr Issues Mol Biol· June 2020

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Synergistic Effects of a Chalkophore, Methanobactin, on Microbial Methylation of Mercury.
Xixiang Yin, Lihong Wang, Lijie Zhang, Hongmei Chen, Xujun Liang, Alan A DiSpirito

Appl Environ Microbiol· May 2020

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Methanobactin from methanotrophs: genetics, structure, function and potential applications.
Jeremy D Semrau, Alan A DiSpirito, Parthiba Karthikeyan Obulisamy, Christina S Kang-Yun

FEMS Microbiol Lett· March 2020

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A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats.
Claudia Einer, Christin Leitzinger, Josef Lichtmannegger, Carola Eberhagen, Tamara Rieder, Alan A DiSpirito

Cell Mol Gastroenterol Hepatol· June 2019

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The role of the NADH-dependent nitrite reductase, Nir, from Escherichia coli in fermentative ammonification.
Xiaoguang Wang, Denis Tamiev, Jagannathan Alagurajan, Alan A DiSpirito, Gregory J Phillips

Arch Microbiol· May 2019

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Long-Term Survival Phase Cells of Salmonella Typhimurium ATCC 14028 Have Significantly Greater Resistance to Ultraviolet Radiation in 0.85% Saline and Apple Juice.
Fei Wang, Aubrey Mendonça, Byron F Brehm-Stecher, James Dickson, Alan DiSpirito

Foodborne Pathog Dis· September 2018

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Methanobactin from Methylosinus trichosporium OB3b inhibits NO reduction in denitrifiers.
Jin Chang, Wenyu Gu, Doyoung Park, Jeremy D Semrau, Alan A DiSpirito

ISME J· August 2018

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Metals and Methanotrophy.
Jeremy D Semrau, Alan A DiSpirito, Wenyu Gu, Sukhwan Yoon

Appl Environ Microbiol· March 2018

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Draft Genome Sequences of Two Gammaproteobacterial Methanotrophs Isolated from Rice Ecosystems.
Katharina Frindte, Marina G Kalyuzhnaya, Françoise Bringel, Peter F Dunfield, Mike S M Jetten, Alan A DiSpirito

Genome Announc· August 2017

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