Publications by authors named "Alan J Hay"

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A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses.
William T Harvey, Vinny Davies, Rodney S Daniels, Lynne Whittaker, Victoria Gregory, Alan J Hay

PLoS Comput Biol· March 2023

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COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment - Meeting report from an isirv-WHO virtual conference.
Jennifer L McKimm-Breschkin, Alan J Hay, Bin Cao, Rebecca J Cox, Jake Dunning, Frederick G Hayden

Antiviral Res· January 2022

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Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group.
Michael G Ison, Frederick G Hayden, Alan J Hay, Larisa V Gubareva, Elena A Govorkova

Antiviral Res· October 2021

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The WHO global influenza surveillance and response system (GISRS)-A future perspective.
Alan J Hay, John W McCauley

Influenza Other Respir Viruses· September 2018

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Identification of Low- and High-Impact Hemagglutinin Amino Acid Substitutions That Drive Antigenic Drift of Influenza A(H1N1) Viruses.
William T Harvey, Donald J Benton, Victoria Gregory, James P J Hall, Rodney S Daniels, Daniel T Haydon, Alan J Hay

PLoS Pathog· April 2016

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Integrating influenza antigenic dynamics with molecular evolution.
Trevor Bedford, Marc A Suchard, Philippe Lemey, Gytis Dudas, Victoria Gregory, Alan J Hay

Elife· November 2015

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Optimisation of a micro-neutralisation assay and its application in antigenic characterisation of influenza viruses.
Yipu Lin, Yan Gu, Stephen A Wharton, Lynne Whittaker, Victoria Gregory, Alan J Hay

Influenza Other Respir Viruses· November 2015

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Changes in the hemagglutinin of H5N1 viruses during human infection--influence on receptor binding.
Martin Crusat, Junfeng Liu, Angelina S Palma, Robert A Childs, Yan Liu, Alan J Hay

Virology· December 2013

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Second isirv antiviral group conference: overview.
Aeron C Hurt, Michael G Ison, Frederick G Hayden, Alan J Hay

Influenza Other Respir Viruses· November 2013

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Oseltamivir resistance during treatment of H7N9 infection.
Alan J Hay, Frederick G Hayden

Lancet· June 2013

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Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin.
Yi Pu Lin, Xiaoli Xiong, Stephen A Wharton, Stephen R Martin, Peter J Coombs, Alan J Hay

Proc Natl Acad Sci U S A· December 2012

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H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.
Erhard van der Vries, Patrick J Collins, Sebastien G Vachieri, Xiaoli Xiong, Junfeng Liu, Alan J Hay

PLoS Pathog· September 2012

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Charting the host adaptation of influenza viruses.
Mario dos Reis, Asif U Tamuri, Alan J Hay, Richard A Goldstein

Mol Biol Evol· June 2011

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[Impact of avian influenza virus H5N1 neuraminidase mutations on the activity of neuraminidase and the sensibility to neuraminidase inhibitors].
Zi Chen, Yu-huang Zheng, Yipu Lin, Patrick J Collins, Alan J Hay

Zhonghua Yi Xue Za Zhi· July 2010

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Comparison of the activities of BM2 protein and its H19 and W23 mutants of influenza B virus with activities of M2 protein and its H37 and W41 mutants of influenza A virus.
Tatiana Betakova, Alan J Hay

Arch Virol· February 2010

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Identifying changes in selective constraints: host shifts in influenza.
Asif U Tamuri, Mario Dos Reis, Alan J Hay, Richard A Goldstein

PLoS Comput Biol· November 2009

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Using non-homogeneous models of nucleotide substitution to identify host shift events: application to the origin of the 1918 'Spanish' influenza pandemic virus.
Mario dos Reis, Alan J Hay, Richard A Goldstein

J Mol Evol· October 2009

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Efficient synthesis of highly active phospha-isosteres of the influenza neuraminidase inhibitor oseltamivir.
Benoit Carbain, Patrick J Collins, Lori Callum, Stephen R Martin, Alan J Hay

ChemMedChem· March 2009

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Characteristics of arbidol-resistant mutants of influenza virus: implications for the mechanism of anti-influenza action of arbidol.
Irina A Leneva, Rupert J Russell, Yury S Boriskin, Alan J Hay

Antiviral Res· February 2009

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Stability and function of the influenza A virus M2 ion channel protein is determined by both extracellular and cytoplasmic domains.
Tatiana Betakova, Alan J Hay

Arch Virol· February 2009

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Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues.
Antonios Kolocouris, Philip Spearpoint, Stephen R Martin, Alan J Hay, Marta López-Querol

Bioorg Med Chem Lett· December 2008

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Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses.
Colin A Russell, Terry C Jones, Ian G Barr, Nancy J Cox, Rebecca J Garten, Alan J Hay

Vaccine· September 2008

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Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Patrick J Collins, Lesley F Haire, Yi Pu Lin, Junfeng Liu, Rupert J Russell, Alan J Hay

Nature· June 2008

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Changing selective pressure during antigenic changes in human influenza H3.
Benjamin P Blackburne, Alan J Hay, Richard A Goldstein

PLoS Pathog· May 2008

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The global circulation of seasonal influenza A (H3N2) viruses.
Colin A Russell, Terry C Jones, Ian G Barr, Nancy J Cox, Rebecca J Garten, Alan J Hay

Science· April 2008

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