Publications by authors named "Rupert J Russell"

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Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Philip S Kerry, Sankar Mohan, Rupert J M Russell, Nicole Bance, Masahiro Niikura

Sci Rep· October 2013

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Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence.
Juan Ayllon, Rupert J Russell, Adolfo García-Sastre, Benjamin G Hale

J Virol· December 2012

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Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility.
Santosh Rudrawar, Philip S Kerry, Marie-Anne Rameix-Welti, Andrea Maggioni, Jeffrey C Dyason, Rupert J M Russell

Org Biomol Chem· November 2012

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Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.
Beenu Bhatt, Raphael Böhm, Philip S Kerry, Jeffrey C Dyason, Rupert J M Russell

J Med Chem· October 2012

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Conservation of a crystallographic interface suggests a role for β-sheet augmentation in influenza virus NS1 multifunctionality.
Philip S Kerry, Elizabeth Long, Margaret A Taylor, Rupert J M Russell

Acta Crystallogr Sect F Struct Biol Cryst Commun· August 2011

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Combinatorial effect of two framework mutations (E119V and I222L) in the neuraminidase active site of H3N2 influenza virus on resistance to oseltamivir.
Mathilde Richard, Olivier Ferraris, Alexandra Erny, Mendy Barthélémy, Aurélien Traversier, Rupert J Russell

Antimicrob Agents Chemother· June 2011

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Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1).
Konrad C Bradley, Cheryl A Jones, S Mark Tompkins, Ralph A Tripp, Rupert J Russell

Virology· May 2011

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A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.
Philip S Kerry, Juan Ayllon, Margaret A Taylor, Claudia Hass, Andrew Lewis, Rupert J Russell

PLoS One· March 2011

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Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Santosh Rudrawar, Jeffrey C Dyason, Marie-Anne Rameix-Welti, Faith J Rose, Philip S Kerry, Rupert J M Russell

Nat Commun· November 2010

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Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein.
Benjamin G Hale, Philip S Kerry, David Jackson, Bernard L Precious, Alexander Gray, Rupert J Russell

Proc Natl Acad Sci U S A· February 2010

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Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K).
David Jackson, Marian J Killip, Caroline S Galloway, Rupert J Russell, Richard E Randall

Virology· January 2010

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Single residue deletions along the length of the influenza HA fusion peptide lead to inhibition of membrane fusion function.
William A Langley, Sudha Thoennes, Konrad C Bradley, Summer E Galloway, Ganesh R Talekar, Rupert J Russell

Virology· November 2009

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Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957.
Junfeng Liu, David J Stevens, Lesley F Haire, Philip A Walker, Peter J Coombs, Rupert J Russell

Proc Natl Acad Sci U S A· October 2009

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Composition and functions of the influenza fusion peptide.
Karen J Cross, William A Langley, Rupert J Russell, John J Skehel, David A Steinhauer

Protein Pept Lett· September 2009

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Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity.
Federico Medda, Rupert J M Russell, Maureen Higgins, Anna R McCarthy, Johanna Campbell

J Med Chem· May 2009

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Characteristics of arbidol-resistant mutants of influenza virus: implications for the mechanism of anti-influenza action of arbidol.
Irina A Leneva, Rupert J Russell, Yury S Boriskin, Alan J Hay

Antiviral Res· February 2009

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Crystal structure of the NanB sialidase from Streptococcus pneumoniae.
Guogang Xu, Jane A Potter, Rupert J M Russell, Marco R Oggioni, Peter W Andrew

J Mol Biol· December 2008

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Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.
Rupert J Russell, Philip S Kerry, David J Stevens, David A Steinhauer, Stephen R Martin

Proc Natl Acad Sci U S A· November 2008

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S-adenosyl-L-methionine:hydroxide adenosyltransferase: a SAM enzyme.
Hai Deng, Catherine H Botting, John T G Hamilton, Rupert J M Russell, David O'Hagan

Angew Chem Int Ed Engl· August 2008

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Structure of an avian influenza A virus NS1 protein effector domain.
Benjamin G Hale, Wendy S Barclay, Richard E Randall, Rupert J Russell

Virology· August 2008

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Length requirements for membrane fusion of influenza virus hemagglutinin peptide linkers to transmembrane or fusion peptide domains.
Zhu-Nan Li, Byeong-Jae Lee, William A Langley, Konrad C Bradley, Rupert J Russell

J Virol· July 2008

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Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Patrick J Collins, Lesley F Haire, Yi Pu Lin, Junfeng Liu, Rupert J Russell

Nature· June 2008

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Infectivity studies of influenza virus hemagglutinin receptor binding site mutants in mice.
Jeffrey Meisner, Kristy J Szretter, Konrad C Bradley, William A Langley, Zhu-Nan Li, Rupert J Russell

J Virol· May 2008

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Evolving complexities of influenza virus and its receptors.
John M Nicholls, Renee W Y Chan, Rupert J Russell, Gillian M Air, J S Malik Peiris

Trends Microbiol· April 2008

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Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion.
Sudha Thoennes, Zhu-Nan Li, Byeong-Jae Lee, William A Langley, John J Skehel, Rupert J Russell

Virology· January 2008

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