Publications by authors named "Juan Ayllon"

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Systemic and mucosal immune signatures of protection against SARS-CoV-2 transmission in humans.
Amaya Rojo-Fernandez, Sadaf Aslam, Fahmida Alam, Alba Escalera, Vicente Villamandos, Juan Ayllon

Cell Rep Med· December 2025

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Influenza A virus NS1 protein mimics oncogenic PI3K resulting in isoform specific cellular redistribution and activation.
Sadaf Aslam, María T Sánchez-Aparicio, Braden D Siempelkamp, Gillian L Dornan, Nikos Tsolakos, Juan Ayllon

Proc Natl Acad Sci U S A· August 2025

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Generation of a high yield vaccine backbone for influenza B virus in embryonated chicken eggs.
Sadaf Aslam, Madhusudan Rajendran, Divya Kriti, Andrew Kurland, Jeffrey Johnson, Juan Ayllon

NPJ Vaccines· February 2023

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Coronavirus as the Possible Causative Agent of the 1889-1894 Pandemic.
Anton Erkoreka, Josu Hernando-Pérez, Juan Ayllon

Infect Dis Rep· June 2022

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Pre-existing Hemagglutinin Stalk Antibodies Correlate with Protection of Lower Respiratory Symptoms in Flu-Infected Transplant Patients.
Teresa Aydillo, Alba Escalera, Shirin Strohmeier, Sadaf Aslam, Javier Sanchez-Cespedes, Juan Ayllon

Cell Rep Med· November 2020

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Activity of human serum antibodies in an influenza virus hemagglutinin stalk-based ADCC reporter assay correlates with activity in a CD107a degranulation assay.
Veronika Chromikova, Jessica Tan, Sadaf Aslam, Arvind Rajabhathor, Maria Bermudez-Gonzalez, Juan Ayllon

Vaccine· February 2020

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Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses.
Raquel Muñoz-Moreno, Carles Martínez-Romero, Daniel Blanco-Melo, Christian V Forst, Raffael Nachbagauer

Cell Rep· December 2019

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Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice.
Guha Asthagiri Arunkumar, Andriani Ioannou, Teddy John Wohlbold, Philip Meade, Sadaf Aslam, Juan Ayllon

J Virol· March 2019

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Influenza virus infection causes global RNAPII termination defects.
Nan Zhao, Vittorio Sebastiano, Natasha Moshkina, Nacho Mena, Judd Hultquist, Juan Ayllon

Nat Struct Mol Biol· September 2018

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Specific Mutations in the PB2 Protein of Influenza A Virus Compensate for the Lack of Efficient Interferon Antagonism of the NS1 Protein of Bat Influenza A-Like Viruses.
Teresa Aydillo, Juan Ayllon, Amzie Pavlisin, Carles Martinez-Romero, Shashank Tripathi

J Virol· April 2018

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Influenza B virus reverse genetic backbones with improved growth properties in the EB66® cell line as basis for vaccine seed virus generation.
Kris M White, Juan Ayllon, Ignacio Mena, Anna Potenski, Florian Krammer

Vaccine· February 2018

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Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity.
Hannah L Turkington, Mindaugas Juozapaitis, Philip S Kerry, Teresa Aydillo, Juan Ayllon

J Virol· October 2015

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Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models.
Sara Cuadrado-Castano, Juan Ayllon, Mena Mansour, Janis de la Iglesia-Vicente, Stefan Jordan

Mol Cancer Ther· May 2015

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The NS1 protein: a multitasking virulence factor.
Juan Ayllon, Adolfo García-Sastre

Curr Top Microbiol Immunol· March 2015

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A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.
Juan Ayllon, Patricia Domingues, Ricardo Rajsbaum, Lisa Miorin, Mirco Schmolke

J Virol· October 2014

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The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon.
Maudry Laurent-Rolle, Juliet Morrison, Ricardo Rajsbaum, Jesica M Levingston Macleod, Giuseppe Pisanelli, Juan Ayllon

Cell Host Microbe· September 2014

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HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes.
Daria Brinzevich, George R Young, Robert Sebra, Juan Ayllon, Susan M Maio

J Virol· June 2014

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New-generation screening assays for the detection of anti-influenza compounds targeting viral and host functions.
Grant Beyleveld, Kris M White, Juan Ayllon, Megan L Shaw

Antiviral Res· October 2013

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Rescue of recombinant Newcastle disease virus from cDNA.
Juan Ayllon, Adolfo García-Sastre, Luis Martínez-Sobrido

J Vis Exp· October 2013

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Identification of small molecules with type I interferon inducing properties by high-throughput screening.
Luis Martínez-Gil, Juan Ayllon, Mila Brum Ortigoza, Adolfo García-Sastre, Megan L Shaw

PLoS One· July 2013

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Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence.
Juan Ayllon, Rupert J Russell, Adolfo García-Sastre, Benjamin G Hale

J Virol· December 2012

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A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon.
Mila Brum Ortigoza, Oliver Dibben, Jad Maamary, Luis Martinez-Gil, Victor H Leyva-Grado, Juan Ayllon

PLoS Pathog· September 2012

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Influenza A viruses and PI3K: are there time, place and manner restrictions?
Juan Ayllon, Adolfo García-Sastre, Benjamin G Hale

Virulence· July 2012

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Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence.
Juan Ayllon, Benjamin G Hale, Adolfo García-Sastre

J Virol· May 2012

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Characterization of chicken endoglin, a member of the zona pellucida family of proteins, and its tissue expression.
Elisa Rossi, Carmen Langa, Alvaro Gilsanz, Francisco J Blanco, Juan Ayllón

Gene· January 2012

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