Publications by authors named "Alan Knox"

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Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis.
Karmel Webb, Miguel Cámara, Nur Masirah M Zain, Nigel Halliday, Kenneth D Bruce, Alan Knox

J Cyst Fibros· July 2022

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and in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis.
Karmel Webb, Nur Masirah M Zain, Iain Stewart, Andrew Fogarty, Edward F Nash, Alan Knox

J Med Microbiol· February 2022

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2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent burden in adults with cystic fibrosis.
Nur Masirah M Zain, Karmel Webb, Iain Stewart, Nigel Halliday, David A Barrett, Alan J Knox

J Med Microbiol· October 2021

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TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma.
Rachel L Clifford, Chen Xi Yang, Nick Fishbane, Jamie Patel, Julia L MacIsaac, Alan J Knox

Clin Epigenetics· October 2020

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Clinical significance of 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis.
Karmel Webb, Andrew Fogarty, David A Barrett, Edward F Nash, Joanna L Whitehouse, Alan Knox

J Med Microbiol· December 2019

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Airway epithelial cell isolation techniques affect DNA methylation profiles with consequences for analysis of asthma related perturbations to DNA methylation.
Rachel L Clifford, Jamie Patel, Julia L MacIsaac, Lisa M McEwen, Simon R Johnson, Alan J Knox

Sci Rep· October 2019

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Epigenetic Changes in Airway Smooth Muscle as a Driver of Airway Inflammation and Remodeling in Asthma.
Klaudia A Kaczmarek, Rachel L Clifford, Alan J Knox

Chest· April 2019

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Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.
Rachel L Clifford, Nick Fishbane, Jamie Patel, Julia L MacIsaac, Lisa M McEwen, Alan J Knox

Clin Epigenetics· February 2019

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Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.
Alice Pasini, Oliver J Brand, Gisli Jenkins, Alan J Knox, Linhua Pang

Biochim Biophys Acta Gene Regul Mech· May 2018

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Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.
William R Coward, Oliver J Brand, Alice Pasini, Gisli Jenkins, Alan J Knox

Am J Respir Cell Mol Biol· April 2018

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PINX1 and TERT Are Required for TNF-α-Induced Airway Smooth Muscle Chemokine Gene Expression.
Karl Deacon, Alan J Knox

J Immunol· February 2018

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FANTOM5 CAGE profiles of human and mouse samples.
Shuhei Noguchi, Takahiro Arakawa, Shiro Fukuda, Masaaki Furuno, Akira Hasegawa, Alan J Knox

Sci Data· August 2017

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Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis.
Helen L Barr, Miguel Cámara, David Barrett, Paul Williams, Doug Forrester, Alan Knox

ERJ Open Res· July 2017

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Role of Rho-Associated Coiled-Coil Forming Kinase Isoforms in Regulation of Stiffness-Induced Myofibroblast Differentiation in Lung Fibrosis.
Su S Htwe, Byung H Cha, Kan Yue, Ali Khademhosseini, Alan J Knox

Am J Respir Cell Mol Biol· June 2017

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Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study.
Helen L Barr, Nigel Halliday, David A Barrett, Paul Williams, Douglas L Forrester, Alan J Knox

J Cyst Fibros· March 2017

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Reflections on Terminology in the Continuing Education of Health Professionals.
Alan B Knox

J Contin Educ Health Prof· November 2016

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Matrix metalloproteinases -8 and -9 in the Airways, Blood and Urine During Exacerbations of COPD.
Jennifer L Cane, Brendan Mallia-Millanes, Douglas L Forrester, Alan J Knox, Charlotte E Bolton

COPD· October 2016

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Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema.
Alison E John, Michael R Wilson, Anthony Habgood, Joanne Porte, Amanda L Tatler, Alan J Knox

Sci Signal· October 2016

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Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation.
Wejdan A Aldajani, Fabián Salazar, Herb F Sewell, Alan Knox, Amir M Ghaemmaghami

Oncotarget· September 2016

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The differential effects of azithromycin on the airway epithelium in vitro and in vivo.
Mariel Slater, Elizabeth Torr, Tim Harrison, Doug Forrester, Alan Knox

Physiol Rep· September 2016

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Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells.
Anna Poghosyan, Jamie K Patel, Rachel L Clifford, Alan J Knox

Biochem Biophys Res Commun· August 2016

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Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression.
Amanda L Tatler, Anthony Habgood, Joanne Porte, Alison E John, Anastasios Stavrou, Alan J Knox

J Biol Chem· April 2016

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Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial.
Doug L Forrester, Alan J Knox, Alan R Smyth, Helen L Barr, Rebecca Simms

Pediatr Pulmonol· March 2016

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Investigating NF-κB signaling in lung fibroblasts in 2D and 3D culture systems.
Su Su Htwe, Helen Harrington, Alan Knox, Felicity Rose, Jonathan Aylott

Respir Res· December 2015

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Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort.
Dominick E Shaw, Ana R Sousa, Stephen J Fowler, Louise J Fleming, Graham Roberts, Alan J Knox

Eur Respir J· November 2015

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