Publications by authors named "Linhua Pang"

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Role of prostanoids, nitric oxide and endothelin pathways in pulmonary hypertension due to COPD.
Abdullah A Alqarni, Abdulelah M Aldhahir, Sara A Alghamdi, Jaber S Alqahtani, Rayan A Siraj, Linhua Pang

Front Med (Lausanne)· October 2023

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Imbalanced prostanoid release mediates cigarette smoke-induced human pulmonary artery cell proliferation.
Abdullah A Alqarni, Oliver J Brand, Alice Pasini, Mushabbab Alahmari, Abdulrhman Alghamdi, Linhua Pang

Respir Res· May 2022

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Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.
Alice Pasini, Oliver J Brand, Gisli Jenkins, Alan J Knox, Linhua Pang

Biochim Biophys Acta Gene Regul Mech· May 2018

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Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.
William R Coward, Oliver J Brand, Alice Pasini, Gisli Jenkins, Alan J Knox, Linhua Pang

Am J Respir Cell Mol Biol· April 2018

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A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.
William R Coward, Carol A Feghali-Bostwick, Gisli Jenkins, Alan J Knox, Linhua Pang

FASEB J· July 2014

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Transcriptional regulation of increased CCL2 expression in pulmonary fibrosis involves nuclear factor-κB and activator protein-1.
Xiaoling Deng, Mingyan Xu, Chao Yuan, Liqin Yin, Xihe Chen, Linhua Pang

Int J Biochem Cell Biol· July 2013

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Inhibition of polyadenylation reduces inflammatory gene induction.
Alexander Kondrashov, Hedda A Meijer, Adeline Barthet-Barateig, Hannah N Parker, Asma Khurshid, Linhua Pang

RNA· December 2012

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Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma.
Amanda L Tatler, Alison E John, Lisa Jolly, Anthony Habgood, Jo Porte, Linhua Pang

J Immunol· December 2011

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TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein.
Deborah L Clarke, Rachel L Clifford, Sarawut Jindarat, David Proud, Linhua Pang

J Biol Chem· September 2010

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Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis.
William R Coward, Keira Watts, Carol A Feghali-Bostwick, Gisli Jenkins, Linhua Pang

Mol Cell Biol· June 2010

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Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, and RNA polymerase II binding to the CXCL8 promoter.
Alison E John, Yong M Zhu, Christopher E Brightling, Linhua Pang, Alan J Knox

J Immunol· October 2009

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Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis.
William R Coward, Keiria Watts, Carol A Feghali-Bostwick, Alan Knox, Linhua Pang

Mol Cell Biol· August 2009

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Beta-tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2-independent mechanism.
Charlotte S Mullan, Michael Riley, Deborah Clarke, Amanda Tatler, Amy Sutcliffe, Linhua Pang

Am J Respir Cell Mol Biol· May 2008

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Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.
Amanda L Tatler, Joanne Porte, Alan Knox, Gisli Jenkins, Linhua Pang

Biochem Biophys Res Commun· May 2008

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Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
Linhua Pang, Mei Nie, Lisa Corbett, Amy Sutcliffe, Alan J Knox

J Immunol· March 2006

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beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation.
Mei Nie, Alan J Knox, Linhua Pang

J Immunol· July 2005

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Interleukin-1beta differentially regulates beta2 adrenoreceptor and prostaglandin E2-mediated cAMP accumulation and chloride efflux from Calu-3 bronchial epithelial cells. Role of receptor changes, adenylyl cyclase, cyclo-oxygenase 2, and protein kinase A.
Andrew Clayton, Elaine Holland, Linhua Pang, Alan Knox

J Biol Chem· June 2005

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Cytokines upregulate vascular endothelial growth factor secretion by human airway smooth muscle cells: Role of endogenous prostanoids.
Joanne Stocks, Dawn Bradbury, Lisa Corbett, Linhua Pang, Alan J Knox

FEBS Lett· May 2005

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Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.
Mei Nie, Lisa Corbett, Alan J Knox, Linhua Pang

J Biol Chem· January 2005

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Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation.
Mei Nie, Linhua Pang, Hiroyasu Inoue, Alan J Knox

Mol Cell Biol· December 2003

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Transcriptional regulation of interleukin (IL)-8 by bradykinin in human airway smooth muscle cells involves prostanoid-dependent activation of AP-1 and nuclear factor (NF)-IL-6 and prostanoid-independent activation of NF-kappaB.
Yong M Zhu, Dawn A Bradbury, Linhua Pang, Alan J Knox

J Biol Chem· August 2003

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Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.
José A Sánchez-Alcázar, Dawn A Bradbury, Linhua Pang, Alan J Knox

Lung Cancer· April 2003

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Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.
Linhua Pang, Mei Nie, Lisa Corbett, Alan J Knox

J Immunol· January 2003

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Glucocorticoid and beta-adrenoceptor agonist interactions in asthma.
Alan J Knox, Linhua Pang

Lancet· October 2002

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Protein kinase C-epsilon mediates bradykinin-induced cyclooxygenase-2 expression in human airway smooth muscle cells.
Linhua Pang, Mei Nie, Lisa Corbett, Richard Donnelly, Samuel Gray

FASEB J· September 2002

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