Publications by authors named "Alan Korman"

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Engineered ipilimumab variants that bind human and mouse CTLA-4.
Brett Robison, S J Diong, Anusha Kumar, Thomas M Moon, Olin Chang, Alan J Korman

MAbs· December 2025

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Endothelial cells as targets of immune checkpoint blockade.
Alan J Korman, Matthew Taylor, F Stephen Hodi

J Immunother Cancer· November 2025

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Fc-optimized checkpoint antibodies for cancer immunotherapy.
Rony Dahan, Alan J Korman

Trends Mol Med· June 2025

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A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression.
Jason R Baird, Alejandro F Alice, Roland Saito, Qingqing Chai, Minhua Han, Alan J Korman

Sci Rep· December 2024

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CD8 T cell targeting of tumor antigens presented by HLA-E.
Ravi F Iyer, Marieke C Verweij, Sujit S Nair, David Morrow, Mandana Mansouri, Alan Korman

Sci Adv· May 2024

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Phase I Study of Single-Agent Anti-Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates.
Julie R Brahmer, Charles G Drake, Ira Wollner, John D Powderly, Joel Picus, Alan J Korman

J Clin Oncol· February 2023

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Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab.
Kent Thudium, Mark Selby, Julie A Zorn, Gregory Rak, Xi-Tao Wang, Alan J Korman

Cancer Immunol Res· October 2022

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The foundations of immune checkpoint blockade and the ipilimumab approval decennial.
Alan J Korman, Sarah C Garrett-Thomson, Nils Lonberg

Nat Rev Drug Discov· July 2022

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Tim-3 mediates T cell trogocytosis to limit antitumor immunity.
Ornella Pagliano, Robert M Morrison, Joe-Marc Chauvin, Hridesh Banerjee, Diwakar Davar, Alan J Korman

J Clin Invest· May 2022

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Author Correction: The foundations of immune checkpoint blockade and the ipilimumab approval decennial.
Alan J Korman, Sarah C Garrett-Thomson, Nils Lonberg

Nat Rev Drug Discov· February 2022

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Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression.
Zoila A Lopez-Bujanda, Michael C Haffner, Matthew G Chaimowitz, Nivedita Chowdhury, Nicholas J Venturini, Alan J Korman

Nat Cancer· August 2021

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Fc-Optimized Anti-CCR8 Antibody Depletes Regulatory T Cells in Human Tumor Models.
Joseph R Campbell, Bryan R McDonald, Paul B Mesko, Nathan O Siemers, Priti B Singh, Alan J Korman

Cancer Res· June 2021

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Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
Iñaki Etxeberria, Elixabet Bolaños, Alvaro Teijeira, Saray Garasa, Alba Yanguas, Alan J Korman

Proc Natl Acad Sci U S A· June 2021

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TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer.
Ralph Ja Maas, Janneke S Hoogstad-van Evert, Jolien Mr Van der Meer, Vera Mekers, Somayeh Rezaeifard, Alan J Korman

Oncoimmunology· November 2020

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Author Correction: Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy.
Anna Galstyan, Janet L Markman, Ekaterina S Shatalova, Antonella Chiechi, Alan J Korman

Nat Commun· November 2020

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IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma.
Joe-Marc Chauvin, Mignane Ka, Ornella Pagliano, Carmine Menna, Quanquan Ding, Alan J Korman

Clin Cancer Res· October 2020

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A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target.
Zachary T Freeman, Thomas R Nirschl, Daniel H Hovelson, Robert J Johnston, John J Engelhardt, Alan J Korman

J Clin Invest· March 2020

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Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV Cancers.
Gabriele Galliverti, Stephan Wullschleger, Mélanie Tichet, Dhaarini Murugan, Nadine Zangger, Alan J Korman

Cancer Immunol Res· January 2020

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Author Correction: Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy.
Anna Galstyan, Janet L Markman, Ekaterina S Shatalova, Antonella Chiechi, Alan J Korman

Nat Commun· January 2020

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Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.
Dhanya K Nambiar, Todd Aguilera, Hongbin Cao, Shirley Kwok, Christina Kong, Alan Korman

J Clin Invest· December 2019

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An Integrative Approach to Inform Optimal Administration of OX40 Agonist Antibodies in Patients with Advanced Solid Tumors.
Rui Wang, Chan Gao, Megan Raymond, Gennaro Dito, Dominic Kabbabe, Alan J Korman

Clin Cancer Res· November 2019

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VISTA is an acidic pH-selective ligand for PSGL-1.
Robert J Johnston, Linhui Julie Su, Jason Pinckney, David Critton, Eric Boyer, Alan J Korman

Nature· October 2019

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Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy.
Anna Galstyan, Janet L Markman, Ekaterina S Shatalova, Antonella Chiechi, Alan J Korman

Nat Commun· August 2019

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CD96 Is an Immune Checkpoint That Regulates CD8 T-cell Antitumor Function.
Deepak Mittal, Ailin Lepletier, Jason Madore, Amelia Roman Aguilera, Kimberley Stannard, Alan Korman

Cancer Immunol Res· April 2019

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New epitopes in ovalbumin provide insights for cancer neoepitopes.
Sukrut Hemant Karandikar, John Sidney, Alessandro Sette, Mark Joseph Selby, Alan Jerry Korman

JCI Insight· March 2019

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