Publications by authors named "Alan Opsahl"

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SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction.
Stephen E Flaherty, Olivier Bezy, Brianna LaCarubba Paulhus, LouJin Song, Mary Piper, Alan Opsahl

Elife· July 2024

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GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia.
Ja Young Kim-Muller, LouJin Song, Brianna LaCarubba Paulhus, Evanthia Pashos, Xiangping Li, Alan Opsahl

Cell Rep· January 2023

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Characterizing Intra-Tumor and Inter-Tumor Variability of Immune Cell Infiltrates in Murine Syngeneic Tumors.
Sepideh Mojtahedzadeh, Alan Opsahl, Joan-Kristel Aguilar, Dingzhou Li, Nicole Streiner

Am J Pathol· December 2021

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Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
Trenton T Ross, Collin Crowley, Kenneth L Kelly, Anthony Rinaldi, David A Beebe, Alan C Opsahl

Cell Mol Gastroenterol Hepatol· November 2021

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Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
Xiaotian Zhong, Srinath Jagarlapudi, Yan Weng, Mellisa Ly, Jason C Rouse, Alan C Opsahl

J Biol Chem· March 2020

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No Evidence of Neurogenesis in Adult Rat Sympathetic Ganglia Following Guanethidine-Induced Neuronal Loss.
Karen M Walters, Magalie Boucher, Germaine G Boucher, Alan C Opsahl, Peter R Mouton

Toxicol Pathol· January 2020

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Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition.
Rachel J Roth Flach, Chunyan Su, Eliza Bollinger, Christian Cortes, Andrew W Robertson, Alan C Opsahl

PLoS One· December 2019

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FGF21 increases water intake, urine output and blood pressure in rats.
Tod Turner, Xian Chen, Matthew Zahner, Alan Opsahl, George DeMarco

PLoS One· February 2019

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Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models.
Ryan M Esquejo, Christopher T Salatto, Jake Delmore, Bina Albuquerque, Allan Reyes, Alan Opsahl

EBioMedicine· May 2018

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From the Cover: Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.
Jon C Cook, Leslie A Obert, Petra Koza-Taylor, Timothy M Coskran, Alan C Opsahl

Toxicol Sci· January 2018

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A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys.
Michael St Andre, Mark Johnson, Prashant N Bansal, Jeremy Wellen, Andrew Robertson, Alan Opsahl

Skelet Muscle· November 2017

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Neurophysiological assessment of sympathetic cardiovascular activity after loss of postganglionic neurons in the anesthetized rat.
Matthew R Zahner, Chang-Ning Liu, Carlin V Okerberg, Alan C Opsahl, Walter F Bobrowski

J Pharmacol Toxicol Methods· May 2017

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Selective Activation of AMPK 1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy.
Christopher T Salatto, Russell A Miller, Kimberly O Cameron, Emily Cokorinos, Allan Reyes, Alan C Opsahl

J Pharmacol Exp Ther· May 2017

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Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.
Emily C Cokorinos, Jake Delmore, Allan R Reyes, Bina Albuquerque, Rasmus Kjøbsted, Alan C Opsahl

Cell Metab· May 2017

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High throughput object-based image analysis of β-amyloid plaques in human and transgenic mouse brain.
Harry D Samaroo, Alan C Opsahl, Jan Schreiber, Sharon M O'Neill, Michael Marconi

J Neurosci Methods· February 2012

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Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice.
Barbara L Bernardo, Timothy S Wachtmann, Patricia G Cosgrove, Max Kuhn, Alan C Opsahl

PLoS One· June 2010

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Differential loss of presynaptic dopaminergic markers in Parkinsonian monkeys.
Diane T Stephenson, Mary Abigail Childs, Qiu Li, Santos Carvajal-Gonzalez, Alan Opsahl

Cell Transplant· June 2007

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Investigating cytoskeletal alterations as a potential marker of retinal and lens drug-related toxicity.
Maria E Verdugo-Gazdik, Damir Simic, Alan C Opsahl, Mark W Tengowski

Assay Drug Dev Technol· December 2006

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Pentamidine reduces hERG expression to prolong the QT interval.
Jason S Cordes, Zhuoqian Sun, David B Lloyd, Jenifer A Bradley, Alan C Opsahl

Br J Pharmacol· May 2005

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Selective cyclooxygenase-2 inhibition does not alter keratinocyte wound responses in the mouse epidermis after abrasion.
Medora M Hardy, Eric A G Blomme, Andrew Lisowski, Kevin S Chinn, Amy Jones, Alan Opsahl

J Pharmacol Exp Ther· March 2003

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