Publications by authors named "Alan Stepto"

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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Youn-Bok Lee, Pranetha Baskaran, Jorge Gomez-Deza, Han-Jou Chen, Agnes L Nishimura, Alan Stepto

Hum Mol Genet· April 2021

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A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
Daniel A Solomon, Alan Stepto, Wing Hei Au, Yoshitsugu Adachi, Danielle C Diaper

Brain· October 2018

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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Youn-Bok Lee, Pranetha Baskaran, Jorge Gomez-Deza, Han-Jou Chen, Agnes L Nishimura, Alan Stepto

Hum Mol Genet· December 2017

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Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia.
Alan Stepto, Jean-Marc Gallo, Christopher E Shaw, Frank Hirth

Acta Neuropathol· March 2014

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Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes.
Danielle C Diaper, Yoshitsugu Adachi, Ben Sutcliffe, Dickon M Humphrey, Christopher J H Elliott, Alan Stepto

Hum Mol Genet· April 2013

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