Publications by authors named "Frank Hirth"

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Cambrian origin of the arachnid brain.
Nicholas J Strausfeld, David R Andrew, Frank Hirth

Curr Biol· December 2025

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Cambrian origin of the arachnid brain.
Nicholas J Strausfeld, David R Andrew, Frank Hirth

Curr Biol· August 2025

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Brain anatomy of the Cambrian fossil Jianfengia multisegmentalis informs euarthropod phylogeny.
Nicholas J Strausfeld, David R Andrew, Xianguang Hou, Frank Hirth

Nat Commun· August 2025

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Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis.
Manpreet Singh Atwal, Jerneja Nimac, Urša Čerček, Sarah Ricarda Goesch, Hannah Rebecca Goesch, Frank Hirth

Front Neurosci· July 2025

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Optogenetic cleavage of the Miro GTPase reveals the direct consequences of real-time loss of function in Drosophila.
Francesca Mattedi, Ethlyn Lloyd-Morris, Frank Hirth, Alessio Vagnoni

PLoS Biol· August 2023

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Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency.
Lucy Granat, Debbra Y Knorr, Daniel C Ranson, Emma L Hamer, Ram Prosad Chakrabarty, Frank Hirth

PLoS Genet· July 2023

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Response to Comment on "The lower Cambrian lobopodian resolves the origin of euarthropod brains".
Nicholas J Strausfeld, Xianguang Hou, Marcel E Sayre, Frank Hirth

Science· June 2023

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Phylogenetic tracing of midbrain-specific regulatory sequences suggests single origin of eubilaterian brains.
Helen C Schuster, Frank Hirth

Sci Adv· May 2023

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The lower Cambrian lobopodian resolves the origin of euarthropod brains.
Nicholas J Strausfeld, Xianguang Hou, Marcel E Sayre, Frank Hirth

Science· November 2022

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Alpha-synucleinopathy reduces NMNAT3 protein levels and neurite formation that can be rescued by targeting the NAD+ pathway.
Richard B Parsons, Altin Kocinaj, Gustavo Ruiz Pulido, Sarah A Prendergast, Anna E Parsons, Frank Hirth

Hum Mol Genet· August 2022

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Karyopherin abnormalities in neurodegenerative proteinopathies.
Terouz Pasha, Anna Zatorska, Daulet Sharipov, Boris Rogelj, Tibor Hortobágyi, Frank Hirth

Brain· November 2021

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Reply to 'TDP43 aggregates: the 'Schrödinger's cat' in amyotrophic lateral sclerosis'.
Paraskevi Tziortzouda, Ludo Van Den Bosch, Frank Hirth

Nat Rev Neurosci· August 2021

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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Youn-Bok Lee, Pranetha Baskaran, Jorge Gomez-Deza, Han-Jou Chen, Agnes L Nishimura, Frank Hirth

Hum Mol Genet· April 2021

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Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation.
Paraskevi Tziortzouda, Ludo Van Den Bosch, Frank Hirth

Nat Rev Neurosci· April 2021

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A miRNA screen procedure identifies as an essential factor in adult glia functions and validates as a beneficial 3Rs model to study glial functions and GBF1 biology.
Catarina Gonçalves-Pimentel, David Mazaud, Benjamin Kottler, Sandra Proelss, Frank Hirth

F1000Res· March 2021

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Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration in .
Jessika C Bridi, Erika Bereczki, Saffron K Smith, Gonçalo M Poças, Benjamin Kottler, Frank Hirth

Brain Commun· March 2021

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Thermoresponsive motor behavior is mediated by ring neuron circuits in the central complex of Drosophila.
Edgar Buhl, Benjamin Kottler, James J L Hodge, Frank Hirth

Sci Rep· January 2021

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Immunostaining of the Embryonic and Larval Drosophila Brain.
Frank Hirth, Danielle C Diaper

Methods Mol Biol· November 2020

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Ancestral regulatory mechanisms specify conserved midbrain circuitry in arthropods and vertebrates.
Jessika C Bridi, Zoe N Ludlow, Benjamin Kottler, Beate Hartmann, Lies Vanden Broeck, Frank Hirth

Proc Natl Acad Sci U S A· August 2020

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Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in .
David Mazaud, Benjamin Kottler, Catarina Gonçalves-Pimentel, Sandra Proelss, Nadine Tüchler, Frank Hirth

J Neurosci· July 2019

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Lineage-specific determination of ring neuron circuitry in the central complex of .
Jessika C Bridi, Zoe N Ludlow, Frank Hirth

Biol Open· July 2019

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Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity.
Matheus C Bianchini, Claudia Ortiz Alves Gularte, Pablo A Nogara, Bárbara N Krum, Mateus C Gayer, Frank Hirth

Metallomics· February 2019

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Inverse Control of Turning Behavior by Dopamine D1 Receptor Signaling in Columnar and Ring Neurons of the Central Complex in Drosophila.
Benjamin Kottler, Richard Faville, Jessika Cristina Bridi, Frank Hirth

Curr Biol· February 2019

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A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
Daniel A Solomon, Alan Stepto, Wing Hei Au, Yoshitsugu Adachi, Danielle C Diaper, Frank Hirth

Brain· October 2018

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expansion of functionally integrated GABAergic interneurons by targeted increase in neural progenitors.
Rachel E Shaw, Benjamin Kottler, Zoe N Ludlow, Edgar Buhl, Dongwook Kim, Frank Hirth

EMBO J· July 2018

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