Publications by authors named "Albert Edge"

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Cellular Reprogramming by Notch Inhibition Regenerates Hair Cells and Afferent Neurons to Restore the Sense of Balance.
Hanae Lahlou, Hong Zhu, Wu Zhou, Albert S B Edge

bioRxiv· September 2025

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Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.
Yen-Fu Cheng, Judith S Kempfle, Hao Chiang, Kohsuke Tani, Quan Wang, Albert S B Edge

PLoS Genet· January 2025

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Pharmacological regeneration of sensory hair cells restores afferent innervation and vestibular function.
Hanae Lahlou, Hong Zhu, Wu Zhou, Albert Sb Edge

J Clin Invest· September 2024

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Auditory hair cells and spiral ganglion neurons regenerate synapses with refined release properties in vitro.
Philippe F Y Vincent, Eric D Young, Albert S B Edge, Elisabeth Glowatzki

Proc Natl Acad Sci U S A· July 2024

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Large-scale annotated dataset for cochlear hair cell detection and classification.
Christopher J Buswinka, David B Rosenberg, Rubina G Simikyan, Richard T Osgood, Katharine Fernandez, Albert S B Edge

Sci Data· April 2024

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A phase I/IIa safety and efficacy trial of intratympanic gamma-secretase inhibitor as a regenerative drug treatment for sensorineural hearing loss.
Anne G M Schilder, Stephan Wolpert, Shakeel Saeed, Leonie M Middelink, Albert S B Edge

Nat Commun· March 2024

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Auditory Hair Cells and Spiral Ganglion Neurons Regenerate Synapses with Refined Release Properties In Vitro.
Philippe F Y Vincent, Eric D Young, Albert S B Edge, Elisabeth Glowatzki

bioRxiv· December 2023

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Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells.
Gurmannat Kalra, Danielle Lenz, Dunia Abdul-Aziz, Craig Hanna, Mahashweta Basu, Albert S B Edge

Cell Rep· November 2023

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Human pluripotent stem cell-derived inner ear organoids recapitulate otic development in vitro.
Daniela Doda, Sara Alonso Jimenez, Hubert Rehrauer, Jose F Carreño, Victoria Valsamides, Albert Edge

Development· October 2023

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Large-scale annotated dataset for cochlear hair cell detection and classification.
Christopher J Buswinka, David B Rosenberg, Rubina G Simikyan, Richard T Osgood, Katharine Fernandez, Albert Sb Edge

bioRxiv· September 2023

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Human pluripotent stem cells-derived inner ear organoids recapitulate otic development .
Daniela Doda, Sara Alonso Jimenez, Hubert Rehrauer, Jose F Carre O, Victoria Valsamides, Albert Edge

bioRxiv· April 2023

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Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs.
Lejo Johnson Chacko, Hanae Lahlou, Claudia Steinacher, Said Assou, Yassine Messat, Albert Edge

Int J Mol Sci· October 2021

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Norrie disease protein is essential for cochlear hair cell maturation.
Yushi Hayashi, Hao Chiang, ChunJie Tian, Artur A Indzhykulian, Albert S B Edge

Proc Natl Acad Sci U S A· September 2021

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Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors.
Silvia T Erni, John C Gill, Carlotta Palaferri, Gabriella Fernandes, Michelle Buri, Albert S B Edge

Front Cell Dev Biol· August 2021

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A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis .
Judith S Kempfle, Marlon V Duro, Andrea Zhang, Carolina D Amador, Richard Kuang, Albert S Edge

Front Cell Neurosci· July 2021

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HIC1 Represses Atoh1 Transcription and Hair Cell Differentiation in the Cochlea.
Dunia Abdul-Aziz, Nicolai Hathiramani, Lauren Phung, Vittoria Sykopetrites, Albert S B Edge

Stem Cell Reports· April 2021

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Trk agonist drugs rescue noise-induced hidden hearing loss.
Katharine A Fernandez, Takahisa Watabe, Mingjie Tong, Xiankai Meng, Kohsuke Tani, Albert Sb Edge

JCI Insight· February 2021

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An antibody to RGMa promotes regeneration of cochlear synapses after noise exposure.
Jerome Nevoux, Mihaela Alexandru, Thomas Bellocq, Lei Tanaka, Yushi Hayashi, Albert S B Edge

Sci Rep· February 2021

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Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells.
Chen-Chi Wu, Aurore Brugeaud, Richard Seist, Hsiao-Chun Lin, Wei-Hsi Yeh, Albert S B Edge

PLoS One· November 2020

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Lin28 reprograms inner ear glia to a neuronal fate.
Judith S Kempfle, Ngoc-Nhi C Luu, Marco Petrillo, Reef Al-Asad, Andrea Zhang, Albert S B Edge

Stem Cells· July 2020

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Regeneration of Cochlear Synapses by Systemic Administration of a Bisphosphonate.
Richard Seist, Mingjie Tong, Lukas D Landegger, Sasa Vasilijic, Hiroshi Hyakusoku, Albert S B Edge

Front Mol Neurosci· July 2020

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Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle.
Jingrong Lu, Lingxiang Hu, Bin Ye, Haixia Hu, Yong Tao, Albert S B Edge

Neuroscience· December 2019

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Increasing the expression level of ChR2 enhances the optogenetic excitability of cochlear neurons.
Xiankai Meng, Swetha Murali, Yen-Fu Cheng, Jingrong Lu, Ariel E Hight, Albert S B Edge

J Neurophysiol· November 2019

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Inner ear organoids: new tools to understand neurosensory cell development, degeneration and regeneration.
Marta Roccio, Albert S B Edge

Development· September 2019

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Engraftment of Human Stem Cell-Derived Otic Progenitors in the Damaged Cochlea.
Alejandra Lopez-Juarez, Hanae Lahlou, Chantal Ripoll, Yves Cazals, Jean Michel Brezun, Albert Edge

Mol Ther· June 2019

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