Publications by authors named "Alberto Leoni"

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Repurposing 1,4-Dihydropyridine Scaffold: 4-Imidazo[2,1-]thiazole-Derivatives from Calcium Entry Blockers to a New Approach for Gut Dysfunctional Motility.
Luca Camarda, Ivan Corazza, Alessandra Locatelli, Alberto Leoni, Maria Frosini

Pharmaceuticals (Basel)· September 2025

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Identification of a new bisindolinone arresting IGROV1 cells proliferation.
Rita Morigi, Chiara Zalambani, Giovanna Farruggia, Laura Verardi, Daniele Esposito, Alberto Leoni

Eur J Med Chem· May 2024

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Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells.
Simona Marzano, Giulia Miglietta, Rita Morigi, Jessica Marinello, Andrea Arleo, Alberto Leoni

J Med Chem· September 2022

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Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity.
Francesca Bonvicini, Alessandra Locatelli, Rita Morigi, Alberto Leoni, Giovanna Angela Gentilomi

Molecules· September 2022

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Synthesis and Biological Evaluation of New Bis-Indolinone Derivatives Endowed with Cytotoxic Activity.
Rita Morigi, Elena Catanzaro, Alessandra Locatelli, Cinzia Calcabrini, Valentina Pellicioni, Alberto Leoni

Molecules· October 2021

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Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis.
Emanuela Pesce, Nicoletta Pedemonte, Alberto Leoni, Alessandra Locatelli, Rita Morigi

Bioorg Med Chem Lett· November 2020

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Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells.
Jussara Amato, Giulia Miglietta, Rita Morigi, Nunzia Iaccarino, Alessandra Locatelli, Alberto Leoni

J Med Chem· March 2020

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4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching.
Alberto Leoni, Maria Frosini, Alessandra Locatelli, Matteo Micucci, Claudio Carotenuto

Eur J Med Chem· May 2019

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Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose.
Alessandra Locatelli, Luisa Iommarini, Alessandra Graziadio, Alberto Leoni, Anna Maria Porcelli

RSC Adv· May 2019

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Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents.
Rita Morigi, Alessandra Locatelli, Alberto Leoni, Mirella Rambaldi, Roberta Bortolozzi

Eur J Med Chem· March 2019

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Synthesis of 3-(Imidazo[2,1-]thiazol-6-yl)-2H-chromen-2-one Derivatives and Study of Their Antiviral Activity against Parvovirus B19.
Ilaria Conti, Rita Morigi, Alessandra Locatelli, Mirella Rambaldi, Gloria Bua, Alberto Leoni

Molecules· March 2019

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Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters.
Alberto Leoni, Roberta Budriesi, Ferruccio Poli, Mariacaterina Lianza, Alessandra Graziadio

Nat Prod Res· September 2018

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Investigation on the Effects of Antimicrobial imidazo[2,1-b]thiazole Derivatives on the Genitourinary Microflora.
Rita Morigi, Beatrice Vitali, Cecilia Prata, Rogers A N Palomino, Alessandra Graziadio, Alberto Leoni

Med Chem· August 2018

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[Community acquired urinary tract infections in older adults].
Alberto Francisco Leoni, Aida Monterisi, Paula G Acuña

Rev Fac Cien Med Univ Nac Cordoba· May 2017

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Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015).
Rita Morigi, Mirella Rambaldi, Alessandra Locatelli, Alberto Leoni

Curr Med Chem· February 2017

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2-Indolinone a versatile scaffold for treatment of cancer: a patent review (2008-2014).
Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi

Expert Opin Ther Pat· September 2016

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Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity.
Rita Morigi, Alessandra Locatelli, Alberto Leoni, Mirella Rambaldi

Recent Pat Anticancer Drug Discov· June 2016

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Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives.
Jussara Amato, Rita Morigi, Bruno Pagano, Alessia Pagano, Stephan Ohnmacht, Alberto Leoni

J Med Chem· June 2016

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Electronic nose and chiral-capillary electrophoresis in evaluation of the quality changes in commercial green tea leaves during a long-term storage.
Mara Mirasoli, Roberto Gotti, Massimo Di Fusco, Alberto Leoni, Carolina Colliva

Talanta· November 2014

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Synthesis and antiproliferative activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives.
Sujeet Kumar, Vidya Gopalakrishnan, Mahesh Hegde, Vivek Rana, Sharad S Dhepe, Alberto Leoni

Bioorg Med Chem Lett· October 2014

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Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex.
Jussara Amato, Nunzia Iaccarino, Bruno Pagano, Rita Morigi, Alessandra Locatelli, Alberto Leoni

Front Chem· August 2014

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Novel thiazole derivatives: a patent review (2008 - 2012. Part 2).
Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi

Expert Opin Ther Pat· July 2014

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Substituted E-3-(3-indolylmethylene)1,3-dihydroindol-2-ones with antiproliferative activity. Study of the effects on HL-60 leukemia cells.
Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi, Concettina Cappadone

Eur J Med Chem· May 2014

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Novel thiazole derivatives: a patent review (2008 - 2012; Part 1).
Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi

Expert Opin Ther Pat· February 2014

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Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles.
Aldo Andreani, Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi

Eur J Med Chem· October 2013

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