Publications by authors named "Alberto Massarotti"

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Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti

Med Res Rev· January 2026

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Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity.
Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Alberto Massarotti

J Nat Prod· November 2025

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Acute Myeloid Leukemia: A Key Role of DGKα and DGKζ in Cell Viability.
Elisa Gorla, Marco Cristiano Cartella, Edoardo Borghetti, Ginevra Lovati, Luisa Racca, Alberto Massarotti

Cells· November 2025

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approach reveals -(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits.
Mahmut Gozelle, Filiz Bakar-Ates, Alberto Massarotti, Erva Ozkan, Habibe Beyza Gunindi

J Biomol Struct Dyn· March 2025

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Symmetrical 2,7-disubstituted 9H-fluoren-9-one as a novel and promising scaffold for selective targeting of SIRT2.
Selen Gozde Kaya, Gokcen Eren, Alberto Massarotti, Habibe Beyza Gunindi, Filiz Bakar-Ates

Arch Pharm (Weinheim)· December 2024

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A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells.
Angela Della Sala, Laura Tasca, Cosmin Butnarasu, Valentina Sala, Giulia Prono, Alberto Massarotti

J Biol Chem· November 2024

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Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1.
Eleonora Panfili, Sarah Jane Rezzi, Annalisa Adamo, Daniele Mazzoletti, Alberto Massarotti

ACS Pharmacol Transl Sci· October 2024

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2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition.
Selen Gozde Kaya, Gokcen Eren, Alberto Massarotti, Filiz Bakar-Ates, Erva Ozkan

Drug Dev Res· June 2024

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The SNAP- technology revised: an effective by using a universal azide-based substrate.
Rosa Merlo, Diego Caprioglio, Michele Cillo, Anna Valenti, Rosanna Mattossovich, Alberto Massarotti

J Enzyme Inhib Med Chem· December 2021

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PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Federico Gulluni, Lorenzo Prever, Huayi Li, Petra Krafcikova, Ilaria Corrado, Alberto Massarotti

Science· December 2021

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The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors.
Silvia Fallarini, Irene P Bhela, Silvio Aprile, Enza Torre, Alice Ranza, Alberto Massarotti

ChemMedChem· November 2021

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Medicinal Chemistry of Isocyanides.
Alberto Massarotti, Francesca Brunelli, Silvio Aprile, Mariateresa Giustiniano, Gian Cesare Tron

Chem Rev· September 2021

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Investigation of the Click-Chemical Space for Drug Design Using ZINClick.
Alberto Massarotti

Methods Mol Biol· April 2021

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What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications.
Marta Serafini, Sarah Cargnin, Alberto Massarotti, Gian Cesare Tron, Tracey Pirali

J Med Chem· April 2021

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Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives.
Valentina Sala, Sophie Julie Cnudde, Alessandra Murabito, Alberto Massarotti, Emilio Hirsch

Eur J Med Chem· March 2021

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Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors.
Suresh Velnati, Alberto Massarotti, Annamaria Antona, Maria Talmon, Luigia Grazia Fresu

J Enzyme Inhib Med Chem· December 2020

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Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function.
Marco Varalda, Annamaria Antona, Valentina Bettio, Konkonika Roy, Ajay Vachamaram, Alberto Massarotti

Front Oncol· October 2020

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Essential Medicinal Chemistry of Essential Medicines.
Marta Serafini, Sarah Cargnin, Alberto Massarotti, Tracey Pirali, Armando A Genazzani

J Med Chem· September 2020

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Bio-Inspired Dual-Selective / G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-]purine Derivatives.
Sveva Pelliccia, Jussara Amato, Domenica Capasso, Sonia Di Gaetano, Alberto Massarotti

J Med Chem· March 2020

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Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to Pharmacodynamic Activity.
Marta Serafini, Enza Torre, Silvio Aprile, Erika Del Grosso, Alessandro Gesù, Alberto Massarotti

J Med Chem· March 2020

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Photocatalytic Isocyanide-Based Multicomponent Domino Cascade toward the Stereoselective Formation of Iminofurans.
Sveva Pelliccia, Antonella Ilenia Alfano, Paolo Luciano, Ettore Novellino, Alberto Massarotti

J Org Chem· February 2020

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ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles.
Doriana Levré, Chiara Arcisto, Valentina Mercalli, Alberto Massarotti

J Chem Inf Model· May 2019

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Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors.
Marta Serafini, Enza Torre, Silvio Aprile, Alberto Massarotti, Silvia Fallarini

Molecules· May 2019

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Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening.
Suresh Velnati, Elisa Ruffo, Alberto Massarotti, Maria Talmon, Konduru Sai Sandeep Varma

Eur J Med Chem· February 2019

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Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach.
Mohammed A Khedr, Alberto Massarotti, Maged E Mohamed

Sci Rep· June 2018

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